FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306768319> ?p ?o ?g. }

• W4306768319 endingPage "1936.e9" @default.
• W4306768319 startingPage "1924" @default.
• W4306768319 abstract "Background and AimsPostpolypectomy risk stratification for subsequent metachronous advanced neoplasia (MAN) is imprecise and does not account for colonoscopist adenoma detection rate (ADR). Our aim was to assess association of ADR with MAN and create a prediction model for postpolypectomy risk stratification incorporating ADR and other factors.MethodsWe conducted a retrospective cohort study of individuals with baseline polypectomy and subsequent surveillance colonoscopy from 2004 to 2016 within the U.S. Department of Veterans Affairs (VA). Clinical factors, polyp findings, and baseline colonoscopist ADR were considered for the model. Model performance (sensitivity, specificity, and area under the curve) for identifying individuals with MAN was compared with 2020 U.S. Multi-Society Task Force on Colorectal Cancer (USMSTF) surveillance recommendations.ResultsA total of 30,897 individuals were randomly assigned 2:1 into independent model training and validation sets. Increasing age, male sex, diabetes, current smoking, adenoma number, polyp location, adenoma ≥10 mm or with tubulovillous/villous features, and decreasing colonoscopist ADR were independently associated with MAN. A range of 1.48- to 1.66-fold increased risk for MAN was observed for ADR in the lowest 3 quintiles (ADR <19.7%–39.3%) vs the highest quintile (ADR >47.0%). When the final model selected based on the training set was applied to the validation set, improved sensitivity and specificity over 2020 USMSTF risk stratification were achieved (P = .001), with an area under the curve of 0.62 (95% confidence interval, 0.60–0.64).ConclusionsColonoscopist ADR is associated with MAN. Combining clinical factors and ADR for risk stratification has potential to improve postpolypectomy risk stratification. Improving ADR is likely to improve postpolypectomy outcomes. Postpolypectomy risk stratification for subsequent metachronous advanced neoplasia (MAN) is imprecise and does not account for colonoscopist adenoma detection rate (ADR). Our aim was to assess association of ADR with MAN and create a prediction model for postpolypectomy risk stratification incorporating ADR and other factors. We conducted a retrospective cohort study of individuals with baseline polypectomy and subsequent surveillance colonoscopy from 2004 to 2016 within the U.S. Department of Veterans Affairs (VA). Clinical factors, polyp findings, and baseline colonoscopist ADR were considered for the model. Model performance (sensitivity, specificity, and area under the curve) for identifying individuals with MAN was compared with 2020 U.S. Multi-Society Task Force on Colorectal Cancer (USMSTF) surveillance recommendations. A total of 30,897 individuals were randomly assigned 2:1 into independent model training and validation sets. Increasing age, male sex, diabetes, current smoking, adenoma number, polyp location, adenoma ≥10 mm or with tubulovillous/villous features, and decreasing colonoscopist ADR were independently associated with MAN. A range of 1.48- to 1.66-fold increased risk for MAN was observed for ADR in the lowest 3 quintiles (ADR <19.7%–39.3%) vs the highest quintile (ADR >47.0%). When the final model selected based on the training set was applied to the validation set, improved sensitivity and specificity over 2020 USMSTF risk stratification were achieved (P = .001), with an area under the curve of 0.62 (95% confidence interval, 0.60–0.64). Colonoscopist ADR is associated with MAN. Combining clinical factors and ADR for risk stratification has potential to improve postpolypectomy risk stratification. Improving ADR is likely to improve postpolypectomy outcomes." @default.
• W4306768319 created "2022-10-19" @default.
• W4306768319 creator A5008519932 @default.
• W4306768319 creator A5010113958 @default.
• W4306768319 creator A5015862864 @default.
• W4306768319 creator A5038787110 @default.
• W4306768319 creator A5039337342 @default.
• W4306768319 creator A5040042320 @default.
• W4306768319 creator A5040647242 @default.
• W4306768319 creator A5052406385 @default.
• W4306768319 creator A5052942563 @default.
• W4306768319 creator A5053725454 @default.
• W4306768319 creator A5060931929 @default.
• W4306768319 creator A5062893408 @default.
• W4306768319 creator A5070266031 @default.
• W4306768319 creator A5072839298 @default.
• W4306768319 creator A5079444927 @default.
• W4306768319 date "2023-07-01" @default.
• W4306768319 modified "2023-10-10" @default.
• W4306768319 title "Adenoma Detection Rate and Clinical Characteristics Influence Advanced Neoplasia Risk After Colorectal Polypectomy" @default.
• W4306768319 cites W119489369 @default.
• W4306768319 cites W1596820466 @default.
• W4306768319 cites W1948109263 @default.
• W4306768319 cites W1976340383 @default.
• W4306768319 cites W2003010633 @default.
• W4306768319 cites W2021550656 @default.
• W4306768319 cites W2040117293 @default.
• W4306768319 cites W2081983433 @default.
• W4306768319 cites W2084058109 @default.
• W4306768319 cites W2099916431 @default.
• W4306768319 cites W2111147183 @default.
• W4306768319 cites W2116899281 @default.
• W4306768319 cites W2117920692 @default.
• W4306768319 cites W2124332203 @default.
• W4306768319 cites W2153022868 @default.
• W4306768319 cites W2158038189 @default.
• W4306768319 cites W2169727689 @default.
• W4306768319 cites W2282223354 @default.
• W4306768319 cites W2337899010 @default.
• W4306768319 cites W2465513780 @default.
• W4306768319 cites W2509999422 @default.
• W4306768319 cites W2518018749 @default.
• W4306768319 cites W2518644196 @default.
• W4306768319 cites W2568726620 @default.
• W4306768319 cites W2589088675 @default.
• W4306768319 cites W2606965403 @default.
• W4306768319 cites W2616159234 @default.
• W4306768319 cites W2788562565 @default.
• W4306768319 cites W2788766073 @default.
• W4306768319 cites W2804385360 @default.
• W4306768319 cites W2916621496 @default.
• W4306768319 cites W2961821249 @default.
• W4306768319 cites W2964976929 @default.
• W4306768319 cites W2977149272 @default.
• W4306768319 cites W2977423544 @default.
• W4306768319 cites W2994685072 @default.
• W4306768319 cites W3005263232 @default.
• W4306768319 cites W3016086297 @default.
• W4306768319 cites W3037959220 @default.
• W4306768319 cites W3091795152 @default.
• W4306768319 cites W3092671624 @default.
• W4306768319 cites W3128646645 @default.
• W4306768319 cites W3136361565 @default.
• W4306768319 cites W3136772227 @default.
• W4306768319 cites W3183775645 @default.
• W4306768319 cites W4231576061 @default.
• W4306768319 cites W854672890 @default.
• W4306768319 doi "https://doi.org/10.1016/j.cgh.2022.10.003" @default.
• W4306768319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36270618" @default.
• W4306768319 hasPublicationYear "2023" @default.
• W4306768319 type Work @default.
• W4306768319 citedByCount "3" @default.
• W4306768319 countsByYear W43067683192023 @default.
• W4306768319 crossrefType "journal-article" @default.
• W4306768319 hasAuthorship W4306768319A5008519932 @default.
• W4306768319 hasAuthorship W4306768319A5010113958 @default.
• W4306768319 hasAuthorship W4306768319A5015862864 @default.
• W4306768319 hasAuthorship W4306768319A5038787110 @default.
• W4306768319 hasAuthorship W4306768319A5039337342 @default.
• W4306768319 hasAuthorship W4306768319A5040042320 @default.
• W4306768319 hasAuthorship W4306768319A5040647242 @default.
• W4306768319 hasAuthorship W4306768319A5052406385 @default.
• W4306768319 hasAuthorship W4306768319A5052942563 @default.
• W4306768319 hasAuthorship W4306768319A5053725454 @default.
• W4306768319 hasAuthorship W4306768319A5060931929 @default.
• W4306768319 hasAuthorship W4306768319A5062893408 @default.
• W4306768319 hasAuthorship W4306768319A5070266031 @default.
• W4306768319 hasAuthorship W4306768319A5072839298 @default.
• W4306768319 hasAuthorship W4306768319A5079444927 @default.
• W4306768319 hasBestOaLocation W43067683191 @default.
• W4306768319 hasConcept C121608353 @default.
• W4306768319 hasConcept C126322002 @default.
• W4306768319 hasConcept C143998085 @default.
• W4306768319 hasConcept C167135981 @default.
• W4306768319 hasConcept C2775969662 @default.
• W4306768319 hasConcept C2776861080 @default.
• W4306768319 hasConcept C2777428134 @default.
• W4306768319 hasConcept C2778435480 @default.

• next