Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306781065> ?p ?o ?g. }
- W4306781065 endingPage "2889" @default.
- W4306781065 startingPage "2875" @default.
- W4306781065 abstract "The first step in phage infection is the recognition of, and adsorption to, a receptor located on the host cell surface. This reversible host adsorption step is commonly followed by an irreversible event, which involves phage DNA delivery or release into the bacterial cytoplasm. The molecular components that trigger this latter event are unknown for most phages of Gram-positive bacteria. In the current study, we present a comparative genome analysis of three mutants of Lactococcus cremoris 3107, which are resistant to the P335 group phage TP901-1 due to mutations that affect TP901-1 DNA release. Through genetic complementation and phage infection assays, a predicted lactococcal three-component glycosylation system (TGS) was shown to be required for TP901-1 infection. Major cell wall saccharidic components were analysed, but no differences were found. However, heterologous gene expression experiments indicate that this TGS is involved in the glucosylation of a cell envelope-associated component that triggers TP901-1 DNA release. To date, a saccharide modification has not been implicated in the DNA delivery process of a Gram-positive infecting phage." @default.
- W4306781065 created "2022-10-19" @default.
- W4306781065 creator A5000041448 @default.
- W4306781065 creator A5004870010 @default.
- W4306781065 creator A5005724388 @default.
- W4306781065 creator A5006922102 @default.
- W4306781065 creator A5007337842 @default.
- W4306781065 creator A5019871566 @default.
- W4306781065 creator A5027154769 @default.
- W4306781065 creator A5031357048 @default.
- W4306781065 creator A5037346430 @default.
- W4306781065 creator A5055342974 @default.
- W4306781065 creator A5061794600 @default.
- W4306781065 creator A5074345479 @default.
- W4306781065 creator A5076997421 @default.
- W4306781065 creator A5078201862 @default.
- W4306781065 creator A5090710117 @default.
- W4306781065 date "2022-10-19" @default.
- W4306781065 modified "2023-10-17" @default.
- W4306781065 title "Host genetic requirements for <scp>DNA</scp> release of lactococcal phage <scp>TP901</scp>‐1" @default.
- W4306781065 cites W1497306643 @default.
- W4306781065 cites W1525355465 @default.
- W4306781065 cites W1697620700 @default.
- W4306781065 cites W1866344862 @default.
- W4306781065 cites W1933893895 @default.
- W4306781065 cites W1958689324 @default.
- W4306781065 cites W1965129893 @default.
- W4306781065 cites W1966121067 @default.
- W4306781065 cites W1966390029 @default.
- W4306781065 cites W1966922544 @default.
- W4306781065 cites W1967257060 @default.
- W4306781065 cites W1972635322 @default.
- W4306781065 cites W1977619080 @default.
- W4306781065 cites W1992856206 @default.
- W4306781065 cites W1994193919 @default.
- W4306781065 cites W2008652124 @default.
- W4306781065 cites W2013713762 @default.
- W4306781065 cites W2024187943 @default.
- W4306781065 cites W2024646097 @default.
- W4306781065 cites W2031347150 @default.
- W4306781065 cites W2050689679 @default.
- W4306781065 cites W2055043387 @default.
- W4306781065 cites W2055463902 @default.
- W4306781065 cites W2056593535 @default.
- W4306781065 cites W2062761029 @default.
- W4306781065 cites W2081445906 @default.
- W4306781065 cites W2082667898 @default.
- W4306781065 cites W2095529535 @default.
- W4306781065 cites W2098584650 @default.
- W4306781065 cites W2100544978 @default.
- W4306781065 cites W2107277218 @default.
- W4306781065 cites W2108234281 @default.
- W4306781065 cites W2112921913 @default.
- W4306781065 cites W2114083522 @default.
- W4306781065 cites W2114570899 @default.
- W4306781065 cites W2120208347 @default.
- W4306781065 cites W2120772351 @default.
- W4306781065 cites W2122726242 @default.
- W4306781065 cites W2123796170 @default.
- W4306781065 cites W2124985265 @default.
- W4306781065 cites W2125085985 @default.
- W4306781065 cites W2127322768 @default.
- W4306781065 cites W2146877297 @default.
- W4306781065 cites W2147805608 @default.
- W4306781065 cites W2154080602 @default.
- W4306781065 cites W2158283772 @default.
- W4306781065 cites W2167096328 @default.
- W4306781065 cites W2170488656 @default.
- W4306781065 cites W2170810106 @default.
- W4306781065 cites W2192080449 @default.
- W4306781065 cites W2291516007 @default.
- W4306781065 cites W2298300023 @default.
- W4306781065 cites W2299259157 @default.
- W4306781065 cites W2389659753 @default.
- W4306781065 cites W2463137550 @default.
- W4306781065 cites W2517162982 @default.
- W4306781065 cites W2587037382 @default.
- W4306781065 cites W2755651139 @default.
- W4306781065 cites W2772134682 @default.
- W4306781065 cites W2782455419 @default.
- W4306781065 cites W2792424526 @default.
- W4306781065 cites W2797865675 @default.
- W4306781065 cites W2806944255 @default.
- W4306781065 cites W2911049251 @default.
- W4306781065 cites W2951277923 @default.
- W4306781065 cites W2965424626 @default.
- W4306781065 cites W2977257606 @default.
- W4306781065 cites W2978617472 @default.
- W4306781065 cites W3011655615 @default.
- W4306781065 cites W3021075530 @default.
- W4306781065 cites W3029480756 @default.
- W4306781065 cites W3033127899 @default.
- W4306781065 cites W3127925013 @default.
- W4306781065 cites W3135569480 @default.
- W4306781065 cites W3176919622 @default.
- W4306781065 cites W3180833969 @default.
- W4306781065 cites W3201757323 @default.
- W4306781065 cites W4234317413 @default.