Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306804786> ?p ?o ?g. }
- W4306804786 endingPage "108066" @default.
- W4306804786 startingPage "108066" @default.
- W4306804786 abstract "In this work, a novel electrochemiluminescence energy resonance transfer (ECL-RET) immunoassay based on ox-MWCNTs-IGQDs and PdAg nanosheets (PdAg NSs) was established for the ultrasensitive detection of 5-fluorouracil (5-FU) in serum. Exposure of graphene quantum dots by nitric acid etching of multi-walled carbon nanotubes to form ox-MWCNTs-IGQDs, which exhibited excellent electrochemiluminescence intensity. The prepared PdAg NSs have the characteristic of large specific surface area and low toxicity. Furthermore, ox-MWCNTs-IGQDs as ECL donor and PdAg NSs as ECL acceptor can directly carry 5-FU coating antigens and antibodies, respectively. Interference due to the introduction of other bridging molecules can be avoided. Based on the principle of competitive immunity, the 5-FU detection substance and 5-FU coating antigen will co-compete for the specific binding site on the scant antibody, realizing the efficient detection of 5-FU. Under optimal conditions, the proposed ECL immunosensor for 5-FU detection exhibited high sensitivity with a wide linear range from 0.0005 ng/mL to 500 ng/mL and a low detection limit at 0.17 pg/mL. This work took a simple approach to design the ECL immunosensor, the sensor had certain feasibility for the detection of 5-FU in the serum of cancer patients, and provided a new way for the detection of other small molecule anticancer drugs in the future." @default.
- W4306804786 created "2022-10-20" @default.
- W4306804786 creator A5004908576 @default.
- W4306804786 creator A5024388478 @default.
- W4306804786 creator A5038622142 @default.
- W4306804786 creator A5040862516 @default.
- W4306804786 creator A5060977332 @default.
- W4306804786 creator A5090037635 @default.
- W4306804786 date "2022-12-01" @default.
- W4306804786 modified "2023-09-26" @default.
- W4306804786 title "Electrochemiluminescence resonance energy transfer system based on ox-MWCNTs-IGQDs and PdAg nanosheets for the detection of 5-fluorouracil in serum" @default.
- W4306804786 cites W102725257 @default.
- W4306804786 cites W1964740554 @default.
- W4306804786 cites W1974506764 @default.
- W4306804786 cites W1975073086 @default.
- W4306804786 cites W1976726453 @default.
- W4306804786 cites W2017108330 @default.
- W4306804786 cites W2024614379 @default.
- W4306804786 cites W2029251919 @default.
- W4306804786 cites W2048000109 @default.
- W4306804786 cites W2065238464 @default.
- W4306804786 cites W2077841486 @default.
- W4306804786 cites W2086702244 @default.
- W4306804786 cites W2127241680 @default.
- W4306804786 cites W2129679102 @default.
- W4306804786 cites W2236696438 @default.
- W4306804786 cites W2316403483 @default.
- W4306804786 cites W2318954152 @default.
- W4306804786 cites W2332774972 @default.
- W4306804786 cites W2336375238 @default.
- W4306804786 cites W2520853106 @default.
- W4306804786 cites W2586031466 @default.
- W4306804786 cites W2591802095 @default.
- W4306804786 cites W2593038210 @default.
- W4306804786 cites W2734900935 @default.
- W4306804786 cites W2743464352 @default.
- W4306804786 cites W2765204913 @default.
- W4306804786 cites W2772488302 @default.
- W4306804786 cites W2808800848 @default.
- W4306804786 cites W2886164236 @default.
- W4306804786 cites W2911439326 @default.
- W4306804786 cites W2946159209 @default.
- W4306804786 cites W2989628308 @default.
- W4306804786 cites W3007621612 @default.
- W4306804786 cites W3036253724 @default.
- W4306804786 cites W3048808677 @default.
- W4306804786 cites W3159181651 @default.
- W4306804786 cites W4200011347 @default.
- W4306804786 cites W4285172501 @default.
- W4306804786 doi "https://doi.org/10.1016/j.microc.2022.108066" @default.
- W4306804786 hasPublicationYear "2022" @default.
- W4306804786 type Work @default.
- W4306804786 citedByCount "3" @default.
- W4306804786 countsByYear W43068047862023 @default.
- W4306804786 crossrefType "journal-article" @default.
- W4306804786 hasAuthorship W4306804786A5004908576 @default.
- W4306804786 hasAuthorship W4306804786A5024388478 @default.
- W4306804786 hasAuthorship W4306804786A5038622142 @default.
- W4306804786 hasAuthorship W4306804786A5040862516 @default.
- W4306804786 hasAuthorship W4306804786A5060977332 @default.
- W4306804786 hasAuthorship W4306804786A5090037635 @default.
- W4306804786 hasConcept C119128265 @default.
- W4306804786 hasConcept C121332964 @default.
- W4306804786 hasConcept C124657808 @default.
- W4306804786 hasConcept C155672457 @default.
- W4306804786 hasConcept C159654299 @default.
- W4306804786 hasConcept C171250308 @default.
- W4306804786 hasConcept C185592680 @default.
- W4306804786 hasConcept C192562407 @default.
- W4306804786 hasConcept C203014093 @default.
- W4306804786 hasConcept C26873012 @default.
- W4306804786 hasConcept C2779892579 @default.
- W4306804786 hasConcept C2780420688 @default.
- W4306804786 hasConcept C30080830 @default.
- W4306804786 hasConcept C38965407 @default.
- W4306804786 hasConcept C43617362 @default.
- W4306804786 hasConcept C513720949 @default.
- W4306804786 hasConcept C86803240 @default.
- W4306804786 hasConceptScore W4306804786C119128265 @default.
- W4306804786 hasConceptScore W4306804786C121332964 @default.
- W4306804786 hasConceptScore W4306804786C124657808 @default.
- W4306804786 hasConceptScore W4306804786C155672457 @default.
- W4306804786 hasConceptScore W4306804786C159654299 @default.
- W4306804786 hasConceptScore W4306804786C171250308 @default.
- W4306804786 hasConceptScore W4306804786C185592680 @default.
- W4306804786 hasConceptScore W4306804786C192562407 @default.
- W4306804786 hasConceptScore W4306804786C203014093 @default.
- W4306804786 hasConceptScore W4306804786C26873012 @default.
- W4306804786 hasConceptScore W4306804786C2779892579 @default.
- W4306804786 hasConceptScore W4306804786C2780420688 @default.
- W4306804786 hasConceptScore W4306804786C30080830 @default.
- W4306804786 hasConceptScore W4306804786C38965407 @default.
- W4306804786 hasConceptScore W4306804786C43617362 @default.
- W4306804786 hasConceptScore W4306804786C513720949 @default.
- W4306804786 hasConceptScore W4306804786C86803240 @default.
- W4306804786 hasLocation W43068047861 @default.
- W4306804786 hasOpenAccess W4306804786 @default.
- W4306804786 hasPrimaryLocation W43068047861 @default.