Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306816492> ?p ?o ?g. }
- W4306816492 endingPage "e0276376" @default.
- W4306816492 startingPage "e0276376" @default.
- W4306816492 abstract "Color morphs in ball pythons ( Python regius ) provide a unique and largely untapped resource for understanding the genetics of coloration in reptiles. Here we use a community-science approach to investigate the genetics of three color morphs affecting production of the pigment melanin. These morphs—Albino, Lavender Albino, and Ultramel—show a loss of melanin in the skin and eyes, ranging from severe (Albino) to moderate (Lavender Albino) to mild (Ultramel). To identify genetic variants causing each morph, we recruited shed skins of pet ball pythons via social media, extracted DNA from the skins, and searched for putative loss-of-function variants in homologs of genes controlling melanin production in other vertebrates. We report that the Albino morph is associated with missense and non-coding variants in the gene TYR . The Lavender Albino morph is associated with a deletion in the gene OCA2 . The Ultramel morph is associated with a missense variant and a putative deletion in the gene TYRP1 . Our study is one of the first to identify genetic variants associated with color morphs in ball pythons and shows that pet samples recruited from the community can provide a resource for genetic studies in this species." @default.
- W4306816492 created "2022-10-20" @default.
- W4306816492 creator A5006751953 @default.
- W4306816492 creator A5038771823 @default.
- W4306816492 creator A5043122778 @default.
- W4306816492 creator A5052745696 @default.
- W4306816492 creator A5058015668 @default.
- W4306816492 creator A5063656186 @default.
- W4306816492 creator A5085090652 @default.
- W4306816492 creator A5087510640 @default.
- W4306816492 date "2022-10-19" @default.
- W4306816492 modified "2023-10-01" @default.
- W4306816492 title "A community-science approach identifies genetic variants associated with three color morphs in ball pythons (Python regius)" @default.
- W4306816492 cites W1266173219 @default.
- W4306816492 cites W1482656728 @default.
- W4306816492 cites W1483826831 @default.
- W4306816492 cites W1518631557 @default.
- W4306816492 cites W1586432619 @default.
- W4306816492 cites W1951418274 @default.
- W4306816492 cites W1965441780 @default.
- W4306816492 cites W1965658412 @default.
- W4306816492 cites W1966442417 @default.
- W4306816492 cites W1968327864 @default.
- W4306816492 cites W1969999847 @default.
- W4306816492 cites W1970534138 @default.
- W4306816492 cites W1973439201 @default.
- W4306816492 cites W1974491933 @default.
- W4306816492 cites W1976955003 @default.
- W4306816492 cites W1977772346 @default.
- W4306816492 cites W1980364613 @default.
- W4306816492 cites W1983313887 @default.
- W4306816492 cites W1990546153 @default.
- W4306816492 cites W1996432911 @default.
- W4306816492 cites W1999232590 @default.
- W4306816492 cites W2007045532 @default.
- W4306816492 cites W2007291915 @default.
- W4306816492 cites W2017454882 @default.
- W4306816492 cites W2022002566 @default.
- W4306816492 cites W2022717619 @default.
- W4306816492 cites W2023560082 @default.
- W4306816492 cites W2026325500 @default.
- W4306816492 cites W2027555131 @default.
- W4306816492 cites W2031082289 @default.
- W4306816492 cites W2037909661 @default.
- W4306816492 cites W2041734888 @default.
- W4306816492 cites W2043584813 @default.
- W4306816492 cites W2044881587 @default.
- W4306816492 cites W2048956046 @default.
- W4306816492 cites W2056573049 @default.
- W4306816492 cites W2065228191 @default.
- W4306816492 cites W2065442102 @default.
- W4306816492 cites W2066422189 @default.
- W4306816492 cites W2071169720 @default.
- W4306816492 cites W2080584000 @default.
- W4306816492 cites W2088012824 @default.
- W4306816492 cites W2088223940 @default.
- W4306816492 cites W2089941045 @default.
- W4306816492 cites W2092453910 @default.
- W4306816492 cites W2097252617 @default.
- W4306816492 cites W2100382193 @default.
- W4306816492 cites W2102810816 @default.
- W4306816492 cites W2103148772 @default.
- W4306816492 cites W2105309456 @default.
- W4306816492 cites W2109627824 @default.
- W4306816492 cites W2110755408 @default.
- W4306816492 cites W2115981775 @default.
- W4306816492 cites W2116744776 @default.
- W4306816492 cites W2123237622 @default.
- W4306816492 cites W2127322768 @default.
- W4306816492 cites W2133931404 @default.
- W4306816492 cites W2137040705 @default.
- W4306816492 cites W2137233414 @default.
- W4306816492 cites W2154143283 @default.
- W4306816492 cites W2155752937 @default.
- W4306816492 cites W2156934255 @default.
- W4306816492 cites W2156970390 @default.
- W4306816492 cites W2158279486 @default.
- W4306816492 cites W2158575160 @default.
- W4306816492 cites W2162098634 @default.
- W4306816492 cites W2165367433 @default.
- W4306816492 cites W2190073527 @default.
- W4306816492 cites W2205497136 @default.
- W4306816492 cites W2211478793 @default.
- W4306816492 cites W2238747072 @default.
- W4306816492 cites W2275412842 @default.
- W4306816492 cites W2396775722 @default.
- W4306816492 cites W2404100678 @default.
- W4306816492 cites W2508629303 @default.
- W4306816492 cites W2520055416 @default.
- W4306816492 cites W2583564935 @default.
- W4306816492 cites W2587244428 @default.
- W4306816492 cites W2607089893 @default.
- W4306816492 cites W2610547935 @default.
- W4306816492 cites W2611924109 @default.
- W4306816492 cites W2619996122 @default.
- W4306816492 cites W2726089438 @default.
- W4306816492 cites W2727365069 @default.
- W4306816492 cites W2737663698 @default.