FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306848268> ?p ?o ?g. }

• W4306848268 endingPage "5112" @default.
• W4306848268 startingPage "5112" @default.
• W4306848268 abstract "Sarcomas are a leading cause of cancer death in individuals younger than 20 years of age and represent the largest group of rare solid tumors. To date, more than 100 morphological subtypes of sarcomas have been described, among which epidemiology, clinical features, management, and prognosis differ significantly. Delays and errors in the diagnosis of sarcomas limit the number of effective therapeutic modalities and catastrophically worsen the prognosis. Therefore, the development of an algorithm for the early accurate diagnosis of sarcomas seems to be as important as the development of novel therapeutic advances. This literature review aims to summarize the results of recent investigations regarding the imaging of sarcoma progression based on the use of X-ray computed tomography (CT) in preclinical studies and in current clinical practice through the lens of cancer hallmarks. We attempted to summarize the main CT imaging features of soft-tissue and bone sarcomas. We noted the development of new molecular markers with high specificity to antibodies and chemokines, which are expressed in particular sarcoma subtypes to reach tumor type-specific imaging. We demonstrate the possibility of the use of X-ray computed microtomography (micro-CT) for non-destructive 3D visualization of solid tumors by increasing the visibility of soft tissues with X-ray scattering agents. Based on the results of recent studies, we hypothesize that micro-CT enables the visualization of neovascularization and stroma formation in sarcomas at high-resolution in vivo and ex vivo, including the novel techniques of whole-block and whole-tissue imaging. Finding correlations between CT, PET/CT, and micro-CT imaging features, the results of the histopathological specimen examination and clinical outcomes may significantly increase the accuracy of soft-tissue and bone tumor diagnostics, which leads to the initiation of appropriate histotype-specific management in a timely manner and, consequently, to improved outcomes." @default.
• W4306848268 created "2022-10-20" @default.
• W4306848268 creator A5014102411 @default.
• W4306848268 creator A5026604647 @default.
• W4306848268 creator A5082485265 @default.
• W4306848268 creator A5086299939 @default.
• W4306848268 creator A5091223989 @default.
• W4306848268 date "2022-10-19" @default.
• W4306848268 modified "2023-09-27" @default.
• W4306848268 title "Imaging Hallmarks of Sarcoma Progression Via X-ray Computed Tomography: Beholding the Flower of Evil" @default.
• W4306848268 cites W1503201230 @default.
• W4306848268 cites W1556529482 @default.
• W4306848268 cites W1580130734 @default.
• W4306848268 cites W1920973919 @default.
• W4306848268 cites W1931765990 @default.
• W4306848268 cites W1965419080 @default.
• W4306848268 cites W1969328947 @default.
• W4306848268 cites W1980495101 @default.
• W4306848268 cites W1980715318 @default.
• W4306848268 cites W1987806206 @default.
• W4306848268 cites W1990175497 @default.
• W4306848268 cites W1994885924 @default.
• W4306848268 cites W199581144 @default.
• W4306848268 cites W2000349758 @default.
• W4306848268 cites W2002331432 @default.
• W4306848268 cites W2007549443 @default.
• W4306848268 cites W2012855647 @default.
• W4306848268 cites W2016384953 @default.
• W4306848268 cites W2033678360 @default.
• W4306848268 cites W2034269086 @default.
• W4306848268 cites W2041241132 @default.
• W4306848268 cites W2054699312 @default.
• W4306848268 cites W2055109713 @default.
• W4306848268 cites W2065447975 @default.
• W4306848268 cites W2069872909 @default.
• W4306848268 cites W2070391025 @default.
• W4306848268 cites W2081269452 @default.
• W4306848268 cites W2084861825 @default.
• W4306848268 cites W2087473738 @default.
• W4306848268 cites W2088303301 @default.
• W4306848268 cites W2089351812 @default.
• W4306848268 cites W2110511446 @default.
• W4306848268 cites W2117692326 @default.
• W4306848268 cites W2119693954 @default.
• W4306848268 cites W2120006816 @default.
• W4306848268 cites W2126438085 @default.
• W4306848268 cites W2126627603 @default.
• W4306848268 cites W2137800448 @default.
• W4306848268 cites W2142986406 @default.
• W4306848268 cites W2143475618 @default.
• W4306848268 cites W2148498673 @default.
• W4306848268 cites W2158251086 @default.
• W4306848268 cites W2158734722 @default.
• W4306848268 cites W2166573361 @default.
• W4306848268 cites W2209435089 @default.
• W4306848268 cites W2259442606 @default.
• W4306848268 cites W2296554413 @default.
• W4306848268 cites W2299781949 @default.
• W4306848268 cites W2330444089 @default.
• W4306848268 cites W2336053791 @default.
• W4306848268 cites W2416982212 @default.
• W4306848268 cites W2467162260 @default.
• W4306848268 cites W2530038458 @default.
• W4306848268 cites W2563661701 @default.
• W4306848268 cites W2563677274 @default.
• W4306848268 cites W2594743616 @default.
• W4306848268 cites W2596213802 @default.
• W4306848268 cites W2752187860 @default.
• W4306848268 cites W2755496220 @default.
• W4306848268 cites W2756390436 @default.
• W4306848268 cites W2759728042 @default.
• W4306848268 cites W2792865967 @default.
• W4306848268 cites W2793086267 @default.
• W4306848268 cites W2804299512 @default.
• W4306848268 cites W2808548961 @default.
• W4306848268 cites W2811295997 @default.
• W4306848268 cites W2907243352 @default.
• W4306848268 cites W2913407178 @default.
• W4306848268 cites W2914058317 @default.
• W4306848268 cites W2923984522 @default.
• W4306848268 cites W2931871459 @default.
• W4306848268 cites W2947289329 @default.
• W4306848268 cites W2948756637 @default.
• W4306848268 cites W2952120339 @default.
• W4306848268 cites W2966618257 @default.
• W4306848268 cites W2974089453 @default.
• W4306848268 cites W2979940269 @default.
• W4306848268 cites W2989699724 @default.
• W4306848268 cites W2995080584 @default.
• W4306848268 cites W2998132351 @default.
• W4306848268 cites W3000391866 @default.
• W4306848268 cites W3007091255 @default.
• W4306848268 cites W3011443620 @default.
• W4306848268 cites W3015411213 @default.
• W4306848268 cites W3025104949 @default.
• W4306848268 cites W3038735633 @default.
• W4306848268 cites W3046643133 @default.
• W4306848268 cites W3048827118 @default.

• next