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• W4306852590 abstract "<sec> <title>BACKGROUND</title> There are a variety of study designs that utilize real-world data. To date, there are limited resources available to aid in the selection and evaluation of these study designs to answer important research and policy questions and differentiating between study designs may be challenging for those new to the field of outcomes research. </sec> <sec> <title>OBJECTIVE</title> Therefore, an interactive tool was built based on published methodologic evidence to fill this gap. </sec> <sec> <title>METHODS</title> The published literature review was evaluated to identify publications related to study designs that utilize real-world data: specifically, pragmatic trials, prospective and retrospective observational studies, and cross-sectional designs. Data from these publications were extracted by two reviewers and qualitatively synthesized to identify themes. These themes were then assembled to build an interactive tool for researchers and decision makers of studies using real-world data. This tool underwent external evaluation and revision in an iterative process to build the final Matrix of Evidence Tool. </sec> <sec> <title>RESULTS</title> The major themes (and subthemes) identified from the literature included data issues (access and data quality), generalizability, outcomes (usability for decision making, long-term outcomes, rare events, specificity of measurement, causal inference), operational issues, bias (compliance, misclassification of exposure, misclassification of outcome, participant selection bias, immortal time bias), and confounding. The Matrix of Evidence tool was built to communicate these themes and is a resource that can be used to evaluate the potential of a particular real-world study design to maximize various aspects of research. </sec> <sec> <title>CONCLUSIONS</title> The key themes identified in the published literature can be evaluated across real-world designs by using the Matrix of Evidence tool. While all aspects of real-world research are not feasible to include, the primary differentiating factors across four common real-world designs are evaluated and compared. Researchers may find this tool valuable in the selection of an appropriate real-world study design given the research question and intent of use of the resulting evidence. </sec>" @default.
• W4306852590 created "2022-10-20" @default.
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• W4306852590 date "2022-09-22" @default.
• W4306852590 modified "2023-10-16" @default.
• W4306852590 title "Matrix of Evidence Tool: Assessing the quality of real-world study designs (Preprint)" @default.
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• W4306852590 cites W1967198369 @default.
• W4306852590 cites W1971071238 @default.
• W4306852590 cites W1972113220 @default.
• W4306852590 cites W1976204773 @default.
• W4306852590 cites W1977240155 @default.
• W4306852590 cites W1977563441 @default.
• W4306852590 cites W1978138475 @default.
• W4306852590 cites W1979013675 @default.
• W4306852590 cites W1979223436 @default.
• W4306852590 cites W19849081 @default.
• W4306852590 cites W1987483992 @default.
• W4306852590 cites W1990506040 @default.
• W4306852590 cites W2007479572 @default.
• W4306852590 cites W2013350088 @default.
• W4306852590 cites W2014514659 @default.
• W4306852590 cites W2019065218 @default.
• W4306852590 cites W2028241223 @default.
• W4306852590 cites W2029375786 @default.
• W4306852590 cites W2029607498 @default.
• W4306852590 cites W2030107954 @default.
• W4306852590 cites W2035836063 @default.
• W4306852590 cites W2035899311 @default.
• W4306852590 cites W2049103906 @default.
• W4306852590 cites W2050361402 @default.
• W4306852590 cites W2058332740 @default.
• W4306852590 cites W2064716317 @default.
• W4306852590 cites W2064790183 @default.
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• W4306852590 cites W2079257641 @default.
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• W4306852590 cites W2082299845 @default.
• W4306852590 cites W2082995348 @default.
• W4306852590 cites W2087427749 @default.
• W4306852590 cites W2092673295 @default.
• W4306852590 cites W2101007849 @default.
• W4306852590 cites W2109522733 @default.
• W4306852590 cites W2111714917 @default.
• W4306852590 cites W2114547039 @default.
• W4306852590 cites W2116810060 @default.
• W4306852590 cites W2118032584 @default.
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• W4306852590 cites W2129499103 @default.
• W4306852590 cites W2131559194 @default.
• W4306852590 cites W2131955313 @default.
• W4306852590 cites W2132565790 @default.
• W4306852590 cites W2134381848 @default.
• W4306852590 cites W2136892596 @default.
• W4306852590 cites W2137559449 @default.
• W4306852590 cites W2140040409 @default.
• W4306852590 cites W2146380789 @default.
• W4306852590 cites W2151315756 @default.
• W4306852590 cites W2153012086 @default.
• W4306852590 cites W2153120342 @default.
• W4306852590 cites W2153149839 @default.
• W4306852590 cites W2153434255 @default.
• W4306852590 cites W2166778781 @default.
• W4306852590 cites W2168416023 @default.
• W4306852590 cites W2172056554 @default.
• W4306852590 cites W2298338128 @default.
• W4306852590 cites W2318707379 @default.
• W4306852590 cites W2319983832 @default.
• W4306852590 cites W2323960083 @default.
• W4306852590 cites W2332804687 @default.
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• W4306852590 doi "https://doi.org/10.2196/preprints.42876" @default.
• W4306852590 hasPublicationYear "2022" @default.
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