FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4306955171> ?p ?o ?g. }

• W4306955171 endingPage "188825" @default.
• W4306955171 startingPage "188825" @default.
• W4306955171 abstract "There has been a growing realization, based on emerging evidence from the point of care, that real-world outcomes of patients with cancer are often inferior to those reported in conventional clinical trials. This phenomenon can be attributed in part to deficits in external validity that are present in many studies. Several factors contribute to external validity deficits, including: narrow eligibility criteria; differences between protocol-specified procedures and routine care; and inadequate access to clinical trial participation among underrepresented and socioeconomically disadvantaged groups. As a result, the current body of clinical evidence derived from conventional clinical trials can be inadequate to inform patient-specific treatment decisions at the point of care. Furthermore, lack of practical guidance on how to evaluate the impact of external validity deficits can impede both the design of more generalizable clinical trials and efforts to personalize treatment decisions for individual patients. In this methodological review, we suggest an approach to aid clinicians in such evaluations, providing visual and quantitative methods for assessing the magnitude of, and adjusting for, the impact of external validity deficits in conventional clinical trials. Our methods and visualizations have broad applicability across important areas of real-world medical decision-making and research, providing opportunities to design clinical studies that are more reflective of the diverse needs of patients with cancer, including those excluded from traditional clinical trials due to narrow eligibility criteria, socioeconomic disadvantages, and other systemic barriers to equitable access to healthcare resources." @default.
• W4306955171 created "2022-10-21" @default.
• W4306955171 creator A5061152769 @default.
• W4306955171 creator A5064260271 @default.
• W4306955171 date "2022-11-01" @default.
• W4306955171 modified "2023-09-28" @default.
• W4306955171 title "A novel approach to reducing disparities in health outcomes by enhancing interpretation of cancer clinical trials for underrepresented patient groups" @default.
• W4306955171 cites W2002062153 @default.
• W4306955171 cites W2004169137 @default.
• W4306955171 cites W2005635141 @default.
• W4306955171 cites W2009569999 @default.
• W4306955171 cites W2015712245 @default.
• W4306955171 cites W2043254260 @default.
• W4306955171 cites W2043990618 @default.
• W4306955171 cites W2051859609 @default.
• W4306955171 cites W2074048861 @default.
• W4306955171 cites W2119851169 @default.
• W4306955171 cites W2123846587 @default.
• W4306955171 cites W2130378535 @default.
• W4306955171 cites W2131738845 @default.
• W4306955171 cites W2139122730 @default.
• W4306955171 cites W2222086386 @default.
• W4306955171 cites W2443962212 @default.
• W4306955171 cites W2607048134 @default.
• W4306955171 cites W2756376311 @default.
• W4306955171 cites W2801697966 @default.
• W4306955171 cites W2890845197 @default.
• W4306955171 cites W2907929014 @default.
• W4306955171 cites W2940871635 @default.
• W4306955171 cites W2952455110 @default.
• W4306955171 cites W2969031691 @default.
• W4306955171 cites W2995028672 @default.
• W4306955171 cites W3127009504 @default.
• W4306955171 doi "https://doi.org/10.1016/j.bbcan.2022.188825" @default.
• W4306955171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36272690" @default.
• W4306955171 hasPublicationYear "2022" @default.
• W4306955171 type Work @default.
• W4306955171 citedByCount "0" @default.
• W4306955171 crossrefType "journal-article" @default.
• W4306955171 hasAuthorship W4306955171A5061152769 @default.
• W4306955171 hasAuthorship W4306955171A5064260271 @default.
• W4306955171 hasConcept C142724271 @default.
• W4306955171 hasConcept C144024400 @default.
• W4306955171 hasConcept C147077947 @default.
• W4306955171 hasConcept C148482608 @default.
• W4306955171 hasConcept C15744967 @default.
• W4306955171 hasConcept C160735492 @default.
• W4306955171 hasConcept C162324750 @default.
• W4306955171 hasConcept C174106493 @default.
• W4306955171 hasConcept C17744445 @default.
• W4306955171 hasConcept C199539241 @default.
• W4306955171 hasConcept C204787440 @default.
• W4306955171 hasConcept C2779318504 @default.
• W4306955171 hasConcept C2780385302 @default.
• W4306955171 hasConcept C2780623907 @default.
• W4306955171 hasConcept C2908647359 @default.
• W4306955171 hasConcept C36289849 @default.
• W4306955171 hasConcept C50522688 @default.
• W4306955171 hasConcept C535046627 @default.
• W4306955171 hasConcept C71924100 @default.
• W4306955171 hasConcept C77805123 @default.
• W4306955171 hasConcept C99454951 @default.
• W4306955171 hasConceptScore W4306955171C142724271 @default.
• W4306955171 hasConceptScore W4306955171C144024400 @default.
• W4306955171 hasConceptScore W4306955171C147077947 @default.
• W4306955171 hasConceptScore W4306955171C148482608 @default.
• W4306955171 hasConceptScore W4306955171C15744967 @default.
• W4306955171 hasConceptScore W4306955171C160735492 @default.
• W4306955171 hasConceptScore W4306955171C162324750 @default.
• W4306955171 hasConceptScore W4306955171C174106493 @default.
• W4306955171 hasConceptScore W4306955171C17744445 @default.
• W4306955171 hasConceptScore W4306955171C199539241 @default.
• W4306955171 hasConceptScore W4306955171C204787440 @default.
• W4306955171 hasConceptScore W4306955171C2779318504 @default.
• W4306955171 hasConceptScore W4306955171C2780385302 @default.
• W4306955171 hasConceptScore W4306955171C2780623907 @default.
• W4306955171 hasConceptScore W4306955171C2908647359 @default.
• W4306955171 hasConceptScore W4306955171C36289849 @default.
• W4306955171 hasConceptScore W4306955171C50522688 @default.
• W4306955171 hasConceptScore W4306955171C535046627 @default.
• W4306955171 hasConceptScore W4306955171C71924100 @default.
• W4306955171 hasConceptScore W4306955171C77805123 @default.
• W4306955171 hasConceptScore W4306955171C99454951 @default.
• W4306955171 hasIssue "6" @default.
• W4306955171 hasLocation W43069551711 @default.
• W4306955171 hasLocation W43069551712 @default.
• W4306955171 hasOpenAccess W4306955171 @default.
• W4306955171 hasPrimaryLocation W43069551711 @default.
• W4306955171 hasRelatedWork W163097115 @default.
• W4306955171 hasRelatedWork W2036261954 @default.
• W4306955171 hasRelatedWork W2142598485 @default.
• W4306955171 hasRelatedWork W2276681575 @default.
• W4306955171 hasRelatedWork W2373699958 @default.
• W4306955171 hasRelatedWork W3040508995 @default.
• W4306955171 hasRelatedWork W3046503103 @default.
• W4306955171 hasRelatedWork W3162537773 @default.
• W4306955171 hasRelatedWork W4244612437 @default.
• W4306955171 hasRelatedWork W4286359460 @default.

• next