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- W4306978312 abstract "Early onset colorectal cancer incidence rates (IR) are rising in the United States. 1 Montminy E.M. et al. Ann Intern Med. 2021; 174: 157-166 Crossref PubMed Scopus (45) Google Scholar Prior early onset colorectal cancer Surveillance Epidemiology and End Results (SEER) studies have combined adenocarcinomas and carcinoids (neuroendocrine tumors) under the umbrella term “colorectal cancer,” which can bias IR interpretations given that only adenocarcinomas are the target of national screening initiatives. Our recent study using SEER 18 demonstrated that both colon and rectal carcinoids are rising at a higher rate than adenocarcinomas in young patients, which underscores the importance of analyzing these subtypes independently if we want to obtain an accurate depiction of colorectal cancer (adenocarcinoma) rates. Furthermore if the appendix anatomic subsite is included in the colon subsite category and histologic stratification is not performed (reporting of appendix subsite use and/or histologic stratification has often been unclear in prior studies using SEER), the presence of appendiceal carcinoids can introduce bias when calculating true colon adenocarcinoma IRs. 2 Sinicrope F.A. N Engl J Med. 2022; 386: 1547-1558 Crossref PubMed Scopus (69) Google Scholar , 3 Wang W. et al. Clin Res Hepatol Gastroenterol. 2019; 43: 208-215 Crossref PubMed Scopus (23) Google Scholar , 4 Bhandari A. et al. J Investig Med. 2017; 65: 311-315 Crossref PubMed Scopus (164) Google Scholar , 5 Murphy C.C. et al. Gastroenterology. 2019; 156: 958-965 Abstract Full Text Full Text PDF PubMed Scopus (95) Google Scholar Hence, we performed age-block annual percent change (APC) and IR analysis of SEER 18 cancer registry datasets to measure the impact that appendiceal carcinoids have on early onset colon cancer (EOCC) IRs if they are included with the colon anatomic subsite." @default.
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- W4306978312 date "2023-10-01" @default.
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- W4306978312 title "Impact of Carcinoid and Appendiceal Site Inclusion on Early Onset Colon Cancer Incidence Rate Analysis in the United States" @default.
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- W4306978312 doi "https://doi.org/10.1016/j.cgh.2022.10.010" @default.
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