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- W4306988992 abstract "Overview The management of soft tissue sarcomas is driven by the anatomic site as well as the histologic subtype of the primary disease. In this chapter, we focus on the importance of a multidisciplinary approach to this diverse group of over 75 different tumor types. We will discuss in this chapter the etiology, clinical presentation, staging, histopathologic classification and prognostic factors for patients with soft tissue sarcoma. Surgery remains paramount to achieving cure for the vast majority of sarcomas. We will discuss how adjunctive therapies, like radiation and chemotherapy can improve overall outcome, as well as highlight the limitations and unanswered questions, both with respect to local recurrence and distant metastases. Where appropriate, we attempt to link specific histologies or molecular changes to the therapeutic approach to disease. We hope to draw attention to the fact that in a field that has traditionally had stagnation in the development of new therapeutic strategies, there has been a renaissance of new molecularly and mechanistically targeted therapies helping to improve outcomes for soft tissue sarcoma patients." @default.
- W4306988992 created "2022-10-22" @default.
- W4306988992 creator A5031649042 @default.
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- W4306988992 creator A5084951029 @default.
- W4306988992 date "2022-10-21" @default.
- W4306988992 modified "2023-10-16" @default.
- W4306988992 title "Soft Tissue Sarcomas" @default.
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