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- W4307000189 abstract "Dengue fever (DF) is a re-emerging disease spread by mosquitoes. It is primarily found in the tropics and subtropics, and its prevalence is heavily influenced by global warming. A comprehensive understanding of how the changes in climate and human population affect future dengue epidemics is crucial for effective prevention and control. In this paper we extend a mechanistic compartmental model for mosquito dynamics of immature and mature stages, coupled with human population dynamics. Stability analysis of the disease-free equilibrium is carried out analytically, and the basic reproduction number is derived. Model parameters are explicitly linked to climatic variables and human population density. Model validation suggests that the basic reproduction number acts as a reliable measure of the spread ability of DF in response to future scenarios of climate and human population change. Our model predicts that the risk area of DF will expand considerably in mainland China, and the expansion fronts are mainly extended in the center and east. Most importantly, sensitivity analysis and model prediction both show that while temperature is critical in determining the threshold suitability for DF transmission, precipitation and human population density act locally to regulate the spreading DF patterns, where high values of these two factors may significantly accelerate the spreading process. Our results indicate a strong call for increased attention in the areas that are currently safe from DF, but climatically suitable for DF spread as consequence of the fast-economic growth and rapid urbanization." @default.
- W4307000189 created "2022-10-22" @default.
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- W4307000189 date "2023-02-01" @default.
- W4307000189 modified "2023-10-16" @default.
- W4307000189 title "Dengue transmission under future climate and human population changes in mainland China" @default.
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- W4307000189 doi "https://doi.org/10.1016/j.apm.2022.10.027" @default.
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