Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307080949> ?p ?o ?g. }
- W4307080949 endingPage "38" @default.
- W4307080949 startingPage "1" @default.
- W4307080949 abstract "Objectives. A powerful analgesic called Morphine causes addiction behaviors and immune suppression as a potential oxidative stressor. Acupuncture showed to inhibit oxidative stress-induced hepatic damage, regulate reactive oxygen species, and attenuate morphine addiction behaviors. Therefore, we investigated the potential effects of acupuncture on morphine-induced immune suppression. Materials and Methods. Rats received morphine intravenously through implanted catheters for 3, 7, or 21 days to determine the optimal condition for morphine-induced immune suppression. Second, we examined whether intravenous (iv.) or intraperitoneal (ip.) administration produced different results. Third, the effects of acupuncture in rats who received morphine for 21 days were investigated. Spleen and submandibular lymph node (S-LN) weights and natural killer (NK) cell activity were measured, and the white pulp diameter, total and cortical spleen thicknesses, and the number of lymphoid follicles in S-LNs were examined. The number of immunoreactive cells was also measured. Results. Decreased organ weights and increased atrophic changes were observed as morphine-induced immune suppression. However, dose-dependent increased immune suppression was not observed between 5.0 mg/kg and 10.0 mg/kg of morphine. And, 3-day withdrawal did not affect. Similar histopathological findings were observed in 5.0 and 10.0 ip. rats when compared to equal dosages of iv., respectively. The morphine induced-immune suppression evidenced by spleen and left S-LN weights, splenic NK cell activities, histopathological findings, and the immunoreactive cell number were normalized by acupuncture. Conclusion. These results indicate that acupuncture inhibits morphine-induced immune suppression, maybe via antioxidative action." @default.
- W4307080949 created "2022-10-24" @default.
- W4307080949 creator A5002062627 @default.
- W4307080949 creator A5005652887 @default.
- W4307080949 creator A5028646657 @default.
- W4307080949 creator A5033434605 @default.
- W4307080949 creator A5036650146 @default.
- W4307080949 creator A5042227235 @default.
- W4307080949 creator A5044144622 @default.
- W4307080949 creator A5072871545 @default.
- W4307080949 creator A5082002684 @default.
- W4307080949 creator A5084423872 @default.
- W4307080949 creator A5091079160 @default.
- W4307080949 date "2022-10-22" @default.
- W4307080949 modified "2023-10-14" @default.
- W4307080949 title "Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System" @default.
- W4307080949 cites W113915385 @default.
- W4307080949 cites W1512387771 @default.
- W4307080949 cites W1539652933 @default.
- W4307080949 cites W1568945049 @default.
- W4307080949 cites W1575585006 @default.
- W4307080949 cites W1782711628 @default.
- W4307080949 cites W1891895434 @default.
- W4307080949 cites W1979297235 @default.
- W4307080949 cites W1979423888 @default.
- W4307080949 cites W1979514172 @default.
- W4307080949 cites W1982281519 @default.
- W4307080949 cites W1982662846 @default.
- W4307080949 cites W1983693109 @default.
- W4307080949 cites W1984111607 @default.
- W4307080949 cites W1987711435 @default.
- W4307080949 cites W2010933451 @default.
- W4307080949 cites W2011985483 @default.
- W4307080949 cites W2013062263 @default.
- W4307080949 cites W2017518807 @default.
- W4307080949 cites W2024611114 @default.
- W4307080949 cites W2027555474 @default.
- W4307080949 cites W2028512348 @default.
- W4307080949 cites W2033279040 @default.
- W4307080949 cites W2035485830 @default.
- W4307080949 cites W2039771930 @default.
- W4307080949 cites W2044936430 @default.
- W4307080949 cites W2048400708 @default.
- W4307080949 cites W2049882600 @default.
- W4307080949 cites W2050881128 @default.
- W4307080949 cites W2052696704 @default.
- W4307080949 cites W2054892603 @default.
- W4307080949 cites W2076276989 @default.
- W4307080949 cites W2081417591 @default.
- W4307080949 cites W2082528248 @default.
- W4307080949 cites W2083054031 @default.
- W4307080949 cites W2085461483 @default.
- W4307080949 cites W2090863496 @default.
- W4307080949 cites W2092080505 @default.
- W4307080949 cites W2093806225 @default.
- W4307080949 cites W2096268441 @default.
- W4307080949 cites W2098052315 @default.
- W4307080949 cites W2099995985 @default.
- W4307080949 cites W2102386365 @default.
- W4307080949 cites W2109843249 @default.
- W4307080949 cites W2118494727 @default.
- W4307080949 cites W2127137621 @default.
- W4307080949 cites W2129791731 @default.
- W4307080949 cites W2130486201 @default.
- W4307080949 cites W2136222064 @default.
- W4307080949 cites W2138473144 @default.
- W4307080949 cites W2139052215 @default.
- W4307080949 cites W2141457548 @default.
- W4307080949 cites W2141649011 @default.
- W4307080949 cites W2153366184 @default.
- W4307080949 cites W2160344511 @default.
- W4307080949 cites W2169167040 @default.
- W4307080949 cites W2192721308 @default.
- W4307080949 cites W2219359490 @default.
- W4307080949 cites W2220427939 @default.
- W4307080949 cites W2404243797 @default.
- W4307080949 cites W2410896755 @default.
- W4307080949 cites W2414279817 @default.
- W4307080949 cites W2416812245 @default.
- W4307080949 cites W2510502610 @default.
- W4307080949 cites W2559984798 @default.
- W4307080949 cites W2608225021 @default.
- W4307080949 cites W2737785069 @default.
- W4307080949 cites W2763300580 @default.
- W4307080949 cites W2767325924 @default.
- W4307080949 cites W2767724659 @default.
- W4307080949 cites W2774442648 @default.
- W4307080949 cites W2789135963 @default.
- W4307080949 cites W2795646289 @default.
- W4307080949 cites W2925263683 @default.
- W4307080949 cites W2971624795 @default.
- W4307080949 cites W3153288137 @default.
- W4307080949 cites W3163089981 @default.
- W4307080949 cites W4298283829 @default.
- W4307080949 doi "https://doi.org/10.1155/2022/7971801" @default.
- W4307080949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36317105" @default.
- W4307080949 hasPublicationYear "2022" @default.
- W4307080949 type Work @default.