FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307227416> ?p ?o ?g. }

• W4307227416 endingPage "126" @default.
• W4307227416 startingPage "105" @default.
• W4307227416 abstract "Sarcocephalus latifolius is one of the most used plants in West African traditional medicine to treat malaria.The aim is to establish a strategy to control the quality of herbal preparations made from S. latifolius.A UHPLC-PDA method was developed for the determination and quantification of the two main bioactive compounds (angustoline and strictosamide) in various parts of the plant. Additionally, an LC-QToF with electrospray ionization method is described for the identification and confirmation of compounds in samples of different parts of the plant.With the UHPLC-PDA method, separation was achieved within 5 min using a C18 column stationary phase at a temperature of 45°C and a gradient system with a mobile phase of water and acetonitrile, both containing 0.1% formic acid. The method was validated for linearity, accuracy, precision (repeatability and intermediate precision), limit of detection (LOD), and limit of quantification (LOQ). The LOD and LOQ of angustoline were found to be 0.3 and 0.8 μg/ml, respectively, and those of strictosamide were found to be 0.1 and 0.3 μg/ml, respectively. Using the LC-QToF method, 90 secondary metabolites, including four isolated compounds from the plant's roots, were identified from leaf, bark, and root samples of S. latifolius.This work is the first to propose a strategy to control the quality of herbal preparations made from S. latifolius. The developed method allows the quantification of the main bioactive compounds and the established chemical profile allows to distinguish the plant from any other species." @default.
• W4307227416 created "2022-10-30" @default.
• W4307227416 creator A5013500556 @default.
• W4307227416 creator A5022645755 @default.
• W4307227416 creator A5022837135 @default.
• W4307227416 creator A5038420905 @default.
• W4307227416 creator A5039173092 @default.
• W4307227416 date "2022-10-25" @default.
• W4307227416 modified "2023-10-16" @default.
• W4307227416 title "Strategy for the quality control of herbal preparations made of <i>Sarcocephalus latifolius</i>: Development and validation of a UHPLC‐PDA method for quantification of angustoline and strictosamide and chemical profiling using LC‐QToF" @default.
• W4307227416 cites W1185126547 @default.
• W4307227416 cites W1960004084 @default.
• W4307227416 cites W1975317910 @default.
• W4307227416 cites W2000029105 @default.
• W4307227416 cites W2015983318 @default.
• W4307227416 cites W2043017677 @default.
• W4307227416 cites W2052833626 @default.
• W4307227416 cites W2057795869 @default.
• W4307227416 cites W2087794389 @default.
• W4307227416 cites W2088931270 @default.
• W4307227416 cites W2092228821 @default.
• W4307227416 cites W2109340340 @default.
• W4307227416 cites W2120399099 @default.
• W4307227416 cites W2126247578 @default.
• W4307227416 cites W2210253908 @default.
• W4307227416 cites W2240324948 @default.
• W4307227416 cites W2293403796 @default.
• W4307227416 cites W2326931786 @default.
• W4307227416 cites W2346584185 @default.
• W4307227416 cites W2352459821 @default.
• W4307227416 cites W2471907590 @default.
• W4307227416 cites W2471936468 @default.
• W4307227416 cites W2763225412 @default.
• W4307227416 cites W2767392333 @default.
• W4307227416 cites W2771331035 @default.
• W4307227416 cites W2776264644 @default.
• W4307227416 cites W2790548353 @default.
• W4307227416 cites W2811509583 @default.
• W4307227416 cites W2900565796 @default.
• W4307227416 cites W2902221417 @default.
• W4307227416 cites W2905141734 @default.
• W4307227416 cites W2954142382 @default.
• W4307227416 cites W3016445774 @default.
• W4307227416 cites W3043036302 @default.
• W4307227416 cites W3093837355 @default.
• W4307227416 cites W3173725817 @default.
• W4307227416 cites W3196068479 @default.
• W4307227416 cites W3217398105 @default.
• W4307227416 cites W4205990725 @default.
• W4307227416 cites W4224274180 @default.
• W4307227416 doi "https://doi.org/10.1002/pca.3183" @default.
• W4307227416 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36281909" @default.
• W4307227416 hasPublicationYear "2022" @default.
• W4307227416 type Work @default.
• W4307227416 citedByCount "0" @default.
• W4307227416 crossrefType "journal-article" @default.
• W4307227416 hasAuthorship W4307227416A5013500556 @default.
• W4307227416 hasAuthorship W4307227416A5022645755 @default.
• W4307227416 hasAuthorship W4307227416A5022837135 @default.
• W4307227416 hasAuthorship W4307227416A5038420905 @default.
• W4307227416 hasAuthorship W4307227416A5039173092 @default.
• W4307227416 hasConcept C119128265 @default.
• W4307227416 hasConcept C154020017 @default.
• W4307227416 hasConcept C162356407 @default.
• W4307227416 hasConcept C185592680 @default.
• W4307227416 hasConcept C2777379063 @default.
• W4307227416 hasConcept C40684141 @default.
• W4307227416 hasConcept C43617362 @default.
• W4307227416 hasConceptScore W4307227416C119128265 @default.
• W4307227416 hasConceptScore W4307227416C154020017 @default.
• W4307227416 hasConceptScore W4307227416C162356407 @default.
• W4307227416 hasConceptScore W4307227416C185592680 @default.
• W4307227416 hasConceptScore W4307227416C2777379063 @default.
• W4307227416 hasConceptScore W4307227416C40684141 @default.
• W4307227416 hasConceptScore W4307227416C43617362 @default.
• W4307227416 hasFunder F4320306113 @default.
• W4307227416 hasFunder F4320309382 @default.
• W4307227416 hasIssue "1" @default.
• W4307227416 hasLocation W43072274161 @default.
• W4307227416 hasLocation W43072274162 @default.
• W4307227416 hasOpenAccess W4307227416 @default.
• W4307227416 hasPrimaryLocation W43072274161 @default.
• W4307227416 hasRelatedWork W1980714464 @default.
• W4307227416 hasRelatedWork W2020128413 @default.
• W4307227416 hasRelatedWork W2055701698 @default.
• W4307227416 hasRelatedWork W2060124471 @default.
• W4307227416 hasRelatedWork W2061951347 @default.
• W4307227416 hasRelatedWork W2064367227 @default.
• W4307227416 hasRelatedWork W2084980675 @default.
• W4307227416 hasRelatedWork W2121688522 @default.
• W4307227416 hasRelatedWork W2155172531 @default.
• W4307227416 hasRelatedWork W3179568669 @default.
• W4307227416 hasVolume "34" @default.
• W4307227416 isParatext "false" @default.
• W4307227416 isRetracted "false" @default.
• W4307227416 workType "article" @default.