Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307230179> ?p ?o ?g. }
- W4307230179 endingPage "113495" @default.
- W4307230179 startingPage "113495" @default.
- W4307230179 abstract "The characterization of bioactive metabolites and the protective effects against Cadmium (Cd) of the hydroalcoholic extract from Allium cepa var. Tropea (Tropea red onion) in human Caco-2 colon adenocarcinoma cells and in vitro antioxidant effects were investigated. Tropea red onion extract showed high levels of bioactive compounds and a strong activity as radical scavenger and inhibitor of lipid peroxidation. The most abundant specialized metabolites were quercetin derivatives. In addition, the extract inhibited NO release in a dose-dependent manner. Exposure of Cd treated human Caco-2 cells to the Tropea red onion extract resulted in a higher cytoprotection with a significant falloff of cells damage produced by Cd. The effect of Tropea red onion evaluated with the MTT assay and LDH test, was time-dependent and more evident after 24h of treatment. Caco-2 cells treated with the Tropea red onion extract and CdCl2 at 24h showed a significant cytoprotection at concentrations equal to 50 μg/mL + 25 μM and 100 μg/mL + 25 μM while at 72h at a concentration of 25 μg/mL + 25 μM. We observed with MTT and LDH assays that treatment of cells with Tropea red onion extract at 24h was able to significantly prevent Cd-induced cytotoxicity alone." @default.
- W4307230179 created "2022-10-30" @default.
- W4307230179 creator A5036522666 @default.
- W4307230179 creator A5043727727 @default.
- W4307230179 creator A5049200791 @default.
- W4307230179 creator A5053713526 @default.
- W4307230179 creator A5067301044 @default.
- W4307230179 creator A5070097584 @default.
- W4307230179 creator A5071285651 @default.
- W4307230179 creator A5079795497 @default.
- W4307230179 date "2022-12-01" @default.
- W4307230179 modified "2023-10-18" @default.
- W4307230179 title "Antioxidant activity and protective effect of the outer scales hydroalcoholic extract of Allium cepa L. var. Tropea on toxicity damage induced by Cadmium in Caco-2 cells" @default.
- W4307230179 cites W1966521314 @default.
- W4307230179 cites W1971200376 @default.
- W4307230179 cites W1972940659 @default.
- W4307230179 cites W1981109490 @default.
- W4307230179 cites W1984569881 @default.
- W4307230179 cites W1989403800 @default.
- W4307230179 cites W1994033421 @default.
- W4307230179 cites W1995528271 @default.
- W4307230179 cites W1996941571 @default.
- W4307230179 cites W1996960515 @default.
- W4307230179 cites W2000518233 @default.
- W4307230179 cites W2003051737 @default.
- W4307230179 cites W2003114754 @default.
- W4307230179 cites W2003340019 @default.
- W4307230179 cites W2006342727 @default.
- W4307230179 cites W2011810121 @default.
- W4307230179 cites W2012714652 @default.
- W4307230179 cites W2013500629 @default.
- W4307230179 cites W2017618453 @default.
- W4307230179 cites W2019600164 @default.
- W4307230179 cites W2025654465 @default.
- W4307230179 cites W2028902216 @default.
- W4307230179 cites W2031153418 @default.
- W4307230179 cites W2033285747 @default.
- W4307230179 cites W2033898136 @default.
- W4307230179 cites W2039693707 @default.
- W4307230179 cites W2071627259 @default.
- W4307230179 cites W2072754176 @default.
- W4307230179 cites W2083832602 @default.
- W4307230179 cites W2212789405 @default.
- W4307230179 cites W2257836874 @default.
- W4307230179 cites W2331298460 @default.
- W4307230179 cites W2341468369 @default.
- W4307230179 cites W2396661243 @default.
- W4307230179 cites W2461611841 @default.
- W4307230179 cites W2461881358 @default.
- W4307230179 cites W2607394075 @default.
- W4307230179 cites W2613019008 @default.
- W4307230179 cites W2738165969 @default.
- W4307230179 cites W2790667410 @default.
- W4307230179 cites W2891644789 @default.
- W4307230179 cites W2988302131 @default.
- W4307230179 cites W2997378167 @default.
- W4307230179 cites W2999613976 @default.
- W4307230179 cites W3008947972 @default.
- W4307230179 cites W3129916408 @default.
- W4307230179 cites W3199139009 @default.
- W4307230179 cites W3204283515 @default.
- W4307230179 doi "https://doi.org/10.1016/j.fct.2022.113495" @default.
- W4307230179 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36280149" @default.
- W4307230179 hasPublicationYear "2022" @default.
- W4307230179 type Work @default.
- W4307230179 citedByCount "1" @default.
- W4307230179 countsByYear W43072301792022 @default.
- W4307230179 crossrefType "journal-article" @default.
- W4307230179 hasAuthorship W4307230179A5036522666 @default.
- W4307230179 hasAuthorship W4307230179A5043727727 @default.
- W4307230179 hasAuthorship W4307230179A5049200791 @default.
- W4307230179 hasAuthorship W4307230179A5053713526 @default.
- W4307230179 hasAuthorship W4307230179A5067301044 @default.
- W4307230179 hasAuthorship W4307230179A5070097584 @default.
- W4307230179 hasAuthorship W4307230179A5071285651 @default.
- W4307230179 hasAuthorship W4307230179A5079795497 @default.
- W4307230179 hasConcept C109316439 @default.
- W4307230179 hasConcept C178790620 @default.
- W4307230179 hasConcept C181674461 @default.
- W4307230179 hasConcept C185592680 @default.
- W4307230179 hasConcept C193176779 @default.
- W4307230179 hasConcept C202751555 @default.
- W4307230179 hasConcept C2776151105 @default.
- W4307230179 hasConcept C2776460402 @default.
- W4307230179 hasConcept C2778004101 @default.
- W4307230179 hasConcept C2780484033 @default.
- W4307230179 hasConcept C2780783641 @default.
- W4307230179 hasConcept C2780829032 @default.
- W4307230179 hasConcept C2780967304 @default.
- W4307230179 hasConcept C2781263971 @default.
- W4307230179 hasConcept C29730261 @default.
- W4307230179 hasConcept C544657597 @default.
- W4307230179 hasConcept C55493867 @default.
- W4307230179 hasConcept C556039675 @default.
- W4307230179 hasConcept C59822182 @default.
- W4307230179 hasConcept C71924100 @default.
- W4307230179 hasConcept C86803240 @default.
- W4307230179 hasConcept C98274493 @default.