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- W4307282612 abstract "Abstract Genetic kinship of ancient individuals can provide insights into their culture and social hierarchy, and is relevant for downstream genetic analyses. However, estimating relatedness from ancient DNA is difficult due to low-coverage, ascertainment bias, or contamination from various sources. Here, we present KIN, a method to estimate the relatedness of a pair of individuals from the identical-by-descent segments they share. KIN accurately classifies up to 3rd-degree relatives using ≥ 0.05 x sequence coverage and differentiates siblings from parent-child. It incorporates additional models to adjust for contamination and detect inbreeding, which improves classification accuracy." @default.
- W4307282612 created "2022-10-31" @default.
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- W4307282612 date "2022-10-24" @default.
- W4307282612 modified "2023-10-18" @default.
- W4307282612 title "KIN: A method to infer relatedness from low-coverage ancient DNA" @default.
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- W4307282612 doi "https://doi.org/10.1101/2022.10.21.513172" @default.
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