FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307299858> ?p ?o ?g. }

• W4307299858 abstract "Abstract Background Decision-makers impose COVID-19 mitigations based on public health indicators such as reported cases, which are sensitive to fluctuations in supply and demand for diagnostic testing, and hospital admissions, which lag infections by up to two weeks. Imposing mitigations too early has unnecessary economic costs, while imposing too late leads to uncontrolled epidemics with unnecessary cases and deaths. Sentinel surveillance of recently-symptomatic individuals in outpatient testing sites may overcome biases and lags in conventional indicators, but the minimal outpatient sentinel surveillance system needed for reliable trend estimation remains unknown. Methods We used a stochastic, compartmental transmission model to evaluate the performance of various surveillance indicators at reliably triggering an alarm in response to, but not before, a step increase in transmission of SARS-CoV-2. The surveillance indicators included hospital admissions, hospital occupancy, and sentinel cases with varying levels of sampling effort capturing 5, 10, 20, 50 or 100% of incident mild cases. We tested 3 levels of transmission increase, 3 population sizes, and condition of either simultaneous transmission increase, or lagged increase in older population. We compared the indicators’ performance at triggering alarm soon after, but not prior, to the transmission increase. Results Compared to surveillance based on hospital admissions, outpatient sentinel surveillance that captured at least 20% of incident mild cases could trigger alarm 2 to 5 days earlier for a mild increase in transmission and 6 days earlier for moderate or strong increase. Sentinel surveillance triggered fewer false alarms and averted more deaths per day spent in mitigation. When transmission increase in older populations lagged increase in younger populations by 14 days, sentinel surveillance extended its lead time over hospital admissions by an additional 2 days. Conclusions Sentinel surveillance of mild symptomatic cases can provide more timely and reliable information on changes in transmission to inform decision-makers in an epidemic like COVID-19." @default.
• W4307299858 created "2022-10-31" @default.
• W4307299858 creator A5009850093 @default.
• W4307299858 creator A5031573878 @default.
• W4307299858 creator A5069793587 @default.
• W4307299858 creator A5077342340 @default.
• W4307299858 creator A5089445800 @default.
• W4307299858 date "2022-10-22" @default.
• W4307299858 modified "2023-10-15" @default.
• W4307299858 title "Design of effective outpatient sentinel surveillance for COVID-19 decision-making: a modeling study" @default.
• W4307299858 cites W1924589045 @default.
• W4307299858 cites W2097446414 @default.
• W4307299858 cites W2112061028 @default.
• W4307299858 cites W2755849266 @default.
• W4307299858 cites W2901174607 @default.
• W4307299858 cites W2950881544 @default.
• W4307299858 cites W3008090866 @default.
• W4307299858 cites W3008443627 @default.
• W4307299858 cites W3010233963 @default.
• W4307299858 cites W3014092698 @default.
• W4307299858 cites W3014842224 @default.
• W4307299858 cites W3017441931 @default.
• W4307299858 cites W3020184843 @default.
• W4307299858 cites W3023488150 @default.
• W4307299858 cites W3025614942 @default.
• W4307299858 cites W3025818509 @default.
• W4307299858 cites W3034304416 @default.
• W4307299858 cites W3035395932 @default.
• W4307299858 cites W3080450849 @default.
• W4307299858 cites W3093610264 @default.
• W4307299858 cites W3099011804 @default.
• W4307299858 cites W3100345427 @default.
• W4307299858 cites W3101716397 @default.
• W4307299858 cites W3102037011 @default.
• W4307299858 cites W3108717657 @default.
• W4307299858 cites W3110046534 @default.
• W4307299858 cites W3111455940 @default.
• W4307299858 cites W3111883190 @default.
• W4307299858 cites W3112589197 @default.
• W4307299858 cites W3115834741 @default.
• W4307299858 cites W3117021508 @default.
• W4307299858 cites W3118598290 @default.
• W4307299858 cites W3119859287 @default.
• W4307299858 cites W3134238461 @default.
• W4307299858 cites W3165656738 @default.
• W4307299858 cites W3178423643 @default.
• W4307299858 cites W3180050536 @default.
• W4307299858 cites W3180761123 @default.
• W4307299858 cites W3198237589 @default.
• W4307299858 cites W3204422999 @default.
• W4307299858 cites W4214940687 @default.
• W4307299858 cites W4220683970 @default.
• W4307299858 cites W4229082137 @default.
• W4307299858 cites W4281288681 @default.
• W4307299858 cites W4282932527 @default.
• W4307299858 cites W4289261145 @default.
• W4307299858 cites W4290648800 @default.
• W4307299858 cites W4296808710 @default.
• W4307299858 doi "https://doi.org/10.1101/2022.10.21.22281330" @default.
• W4307299858 hasPublicationYear "2022" @default.
• W4307299858 type Work @default.
• W4307299858 citedByCount "0" @default.
• W4307299858 crossrefType "posted-content" @default.
• W4307299858 hasAuthorship W4307299858A5009850093 @default.
• W4307299858 hasAuthorship W4307299858A5031573878 @default.
• W4307299858 hasAuthorship W4307299858A5069793587 @default.
• W4307299858 hasAuthorship W4307299858A5077342340 @default.
• W4307299858 hasAuthorship W4307299858A5089445800 @default.
• W4307299858 hasBestOaLocation W43072998581 @default.
• W4307299858 hasConcept C126322002 @default.
• W4307299858 hasConcept C160735492 @default.
• W4307299858 hasConcept C162324750 @default.
• W4307299858 hasConcept C194828623 @default.
• W4307299858 hasConcept C2779134260 @default.
• W4307299858 hasConcept C2908647359 @default.
• W4307299858 hasConcept C2909321700 @default.
• W4307299858 hasConcept C3008058167 @default.
• W4307299858 hasConcept C41008148 @default.
• W4307299858 hasConcept C50522688 @default.
• W4307299858 hasConcept C524204448 @default.
• W4307299858 hasConcept C545542383 @default.
• W4307299858 hasConcept C71924100 @default.
• W4307299858 hasConcept C761482 @default.
• W4307299858 hasConcept C76155785 @default.
• W4307299858 hasConcept C99454951 @default.
• W4307299858 hasConceptScore W4307299858C126322002 @default.
• W4307299858 hasConceptScore W4307299858C160735492 @default.
• W4307299858 hasConceptScore W4307299858C162324750 @default.
• W4307299858 hasConceptScore W4307299858C194828623 @default.
• W4307299858 hasConceptScore W4307299858C2779134260 @default.
• W4307299858 hasConceptScore W4307299858C2908647359 @default.
• W4307299858 hasConceptScore W4307299858C2909321700 @default.
• W4307299858 hasConceptScore W4307299858C3008058167 @default.
• W4307299858 hasConceptScore W4307299858C41008148 @default.
• W4307299858 hasConceptScore W4307299858C50522688 @default.
• W4307299858 hasConceptScore W4307299858C524204448 @default.
• W4307299858 hasConceptScore W4307299858C545542383 @default.
• W4307299858 hasConceptScore W4307299858C71924100 @default.
• W4307299858 hasConceptScore W4307299858C761482 @default.
• W4307299858 hasConceptScore W4307299858C76155785 @default.

• next