FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307301347> ?p ?o ?g. }

• W4307301347 abstract "Abstract Background: Respiratory distress syndrome (RDS) is a significant cause of preterm neonatal morbidity and mortality globally. Measures like the use of antenatal corticosteroids (ACS) and immediate resuscitation of the newborn after birth are taken to abate preterm related complications. Most studies that evidenced the benefit of ACS were done in high resource settings. However, some studies in low resource settings reported no benefit of ACS in improving preterm neonatal outcomes. Therefore, this study was conducted to assess the effectiveness of ACS in reducing RDS and neonatal mortality in preterm neonates in resource-limited settings. Methods: A three months nested case-control study (1:2 unmatched) was conducted at Muhimbili National Hospital and Amana regional referral hospital in Dar es salaam, Tanzania. Neonates delivered at 28 to 34 gestational weeks were enrolled and followed up until discharge. Cases were neonates with RDS and controls were those without. Data analysis was done using the statistical package of social sciences version 23. Logistic regression analysis was used to determine the predictors of RDS among preterm neonates. All tests were considered statistically significant at p <0.05. Results: Out of 330 preterm neonates enrolled, 110 were cases and 220 were controls. The median gestational age at delivery was 30 weeks and 6 days (28-34) among cases and 33 weeks (28-34) among controls. One-minute APGAR score of less than 7 (AOR: 3.11; 95% CI 1.54-6.30), and neonatal birth weight (AOR: 0.998; 95% CI 0.997-0.999) were significantly associated with RDS. No significant association was observed between ACS exposure and RDS occurrence (AOR: 0.81; 95% CI 0.69-0.94). The overall mortality rate was 9 per 1000 neonates. Neonatal mortality occurred only among cases whereby, a unit increase in gestational age was associated with a 30% reduction in neonatal mortality (Adjusted hazard ratio, AHR: 0.70, 95% CI: 0.5-0.92, p=0.011). Conclusion: Decrease in gestational age, one minute APGAR score of < 7 and low birth weight were associated with RDS among preterm neonates. ACS was not associated with reduced RDS occurrence and neonatal mortality rates. Moreover, increase in gestation age was the only factor found to be protective against preterm neonatal mortality." @default.
• W4307301347 created "2022-10-31" @default.
• W4307301347 creator A5020990382 @default.
• W4307301347 creator A5023082709 @default.
• W4307301347 creator A5025686236 @default.
• W4307301347 creator A5048148979 @default.
• W4307301347 creator A5050428616 @default.
• W4307301347 creator A5060657310 @default.
• W4307301347 creator A5063680269 @default.
• W4307301347 creator A5063769175 @default.
• W4307301347 creator A5072975112 @default.
• W4307301347 creator A5077433476 @default.
• W4307301347 date "2022-10-26" @default.
• W4307301347 modified "2023-09-26" @default.
• W4307301347 title "Effectiveness of Antenatal Dexamethasone in Reducing Respiratory Distress Syndrome and Mortality in Preterm Neonates: a Nested Case Control Study" @default.
• W4307301347 cites W126571023 @default.
• W4307301347 cites W2086004537 @default.
• W4307301347 cites W2120218708 @default.
• W4307301347 cites W2137608961 @default.
• W4307301347 cites W2511927214 @default.
• W4307301347 cites W2772347081 @default.
• W4307301347 cites W2793749897 @default.
• W4307301347 cites W2951404474 @default.
• W4307301347 cites W2971869909 @default.
• W4307301347 cites W2991112941 @default.
• W4307301347 cites W3092665623 @default.
• W4307301347 cites W3119221766 @default.
• W4307301347 doi "https://doi.org/10.21203/rs.3.rs-2061321/v1" @default.
• W4307301347 hasPublicationYear "2022" @default.
• W4307301347 type Work @default.
• W4307301347 citedByCount "0" @default.
• W4307301347 crossrefType "posted-content" @default.
• W4307301347 hasAuthorship W4307301347A5020990382 @default.
• W4307301347 hasAuthorship W4307301347A5023082709 @default.
• W4307301347 hasAuthorship W4307301347A5025686236 @default.
• W4307301347 hasAuthorship W4307301347A5048148979 @default.
• W4307301347 hasAuthorship W4307301347A5050428616 @default.
• W4307301347 hasAuthorship W4307301347A5060657310 @default.
• W4307301347 hasAuthorship W4307301347A5063680269 @default.
• W4307301347 hasAuthorship W4307301347A5063769175 @default.
• W4307301347 hasAuthorship W4307301347A5072975112 @default.
• W4307301347 hasAuthorship W4307301347A5077433476 @default.
• W4307301347 hasBestOaLocation W43073013471 @default.
• W4307301347 hasConcept C126322002 @default.
• W4307301347 hasConcept C131872663 @default.
• W4307301347 hasConcept C141983124 @default.
• W4307301347 hasConcept C146304588 @default.
• W4307301347 hasConcept C165617652 @default.
• W4307301347 hasConcept C187212893 @default.
• W4307301347 hasConcept C2778052368 @default.
• W4307301347 hasConcept C2778376644 @default.
• W4307301347 hasConcept C2779083892 @default.
• W4307301347 hasConcept C2779234561 @default.
• W4307301347 hasConcept C2780395437 @default.
• W4307301347 hasConcept C42219234 @default.
• W4307301347 hasConcept C54355233 @default.
• W4307301347 hasConcept C66322754 @default.
• W4307301347 hasConcept C71924100 @default.
• W4307301347 hasConcept C86803240 @default.
• W4307301347 hasConceptScore W4307301347C126322002 @default.
• W4307301347 hasConceptScore W4307301347C131872663 @default.
• W4307301347 hasConceptScore W4307301347C141983124 @default.
• W4307301347 hasConceptScore W4307301347C146304588 @default.
• W4307301347 hasConceptScore W4307301347C165617652 @default.
• W4307301347 hasConceptScore W4307301347C187212893 @default.
• W4307301347 hasConceptScore W4307301347C2778052368 @default.
• W4307301347 hasConceptScore W4307301347C2778376644 @default.
• W4307301347 hasConceptScore W4307301347C2779083892 @default.
• W4307301347 hasConceptScore W4307301347C2779234561 @default.
• W4307301347 hasConceptScore W4307301347C2780395437 @default.
• W4307301347 hasConceptScore W4307301347C42219234 @default.
• W4307301347 hasConceptScore W4307301347C54355233 @default.
• W4307301347 hasConceptScore W4307301347C66322754 @default.
• W4307301347 hasConceptScore W4307301347C71924100 @default.
• W4307301347 hasConceptScore W4307301347C86803240 @default.
• W4307301347 hasLocation W43073013471 @default.
• W4307301347 hasOpenAccess W4307301347 @default.
• W4307301347 hasPrimaryLocation W43073013471 @default.
• W4307301347 hasRelatedWork W1581626317 @default.
• W4307301347 hasRelatedWork W1974541157 @default.
• W4307301347 hasRelatedWork W2158317124 @default.
• W4307301347 hasRelatedWork W2166575736 @default.
• W4307301347 hasRelatedWork W2883482456 @default.
• W4307301347 hasRelatedWork W3029075858 @default.
• W4307301347 hasRelatedWork W3112314028 @default.
• W4307301347 hasRelatedWork W3196023446 @default.
• W4307301347 hasRelatedWork W2270393091 @default.
• W4307301347 hasRelatedWork W2597094303 @default.
• W4307301347 isParatext "false" @default.
• W4307301347 isRetracted "false" @default.
• W4307301347 workType "article" @default.