Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307313355> ?p ?o ?g. }
- W4307313355 abstract "Abstract Brown adipose tissue (BAT) remains active in adults, oxidizing fatty acids or glucose and releasing energy in the form of heat. Brown adipocytes and enhanced thermogenesis are targets for treating obesity and its comorbidities. BAT shows high synthesis activity and secretes several signaling molecules. The brown adipokines, or batokines, take action in an autocrine, paracrine, and endocrine manner. Batokines have a role in the homeostasis of the cardiovascular system, central nervous system, white adipose tissue, liver, and skeletal muscle and exert beneficial effects on BAT. The systemic function of batokines gives BAT an endocrine organ profile. Besides, the batokines Fibroblast Growth Factor-21, Vascular Endothelial Growth Factor A, Bone Morphogenetic Protein 8, Neuregulin 4, Myostatin, and Interleukin-6 emerge as targets to treat obesity and its comorbidities, deserving attention. This review outlines the role of six emerging batokines on BAT and their cross-talk with other organs, focusing on their physiological significance and diet-induced changes." @default.
- W4307313355 created "2022-10-31" @default.
- W4307313355 creator A5048659788 @default.
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- W4307313355 creator A5072346695 @default.
- W4307313355 creator A5084203631 @default.
- W4307313355 date "2022-10-26" @default.
- W4307313355 modified "2023-09-30" @default.
- W4307313355 title "Brown adipose tissue as an endocrine organ: updates on the emerging role of batokines" @default.
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- W4307313355 doi "https://doi.org/10.1515/hmbci-2022-0044" @default.
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