Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307347845> ?p ?o ?g. }
- W4307347845 endingPage "730" @default.
- W4307347845 startingPage "721" @default.
- W4307347845 abstract "Rationale: Indoor air pollution represents a modifiable risk factor for respiratory morbidity in chronic obstructive pulmonary disease (COPD). The effects of indoor air pollution, as well as the impact of interventions to improve indoor air quality, on cardiovascular morbidity in COPD remain unknown. Objectives: To determine the association between indoor particulate matter (PM) and heart rate variability (HRV), a measure of cardiac autonomic function tied to cardiovascular morbidity and mortality, as well as the impact of household air purifiers on HRV. Methods: Former smokers with moderate-severe COPD were recruited from a 6-month randomized controlled trial of a portable air cleaner intervention to undergo paired assessment of both in-home PM and HRV using 24-hour Holter monitoring at up to five time points. Primary outcomes were HRV measures tied to cardiovascular morbidity (standard deviation of normal-to-normal intervals [SDNN] and root mean square of successive differences between normal-to-normal intervals [RMSSD]). Measurements and Results: Eighty-five participants contributed 317 HRV measurements. A twofold increase in household PM ⩽2.5 µm in aerodynamic diameter was associated with decreases in SDNN (β, -2.98% [95% confidence interval (CI), -5.12 to -0.78]) and RMSSD (β, -4.57% [95% CI, -10.1 to -1.60]). The greatest effects were observed with ultrafine particles (<100 nm) (RMSSD; β, -16.4% [95% CI, -22.3 to -10.1]) and among obese participants. Participants randomized to the active air cleaner saw improvements in RMSSD (β, 25.2% [95% CI, 2.99 to 52.1]), but not SDNN (β, 2.65% [95% CI, -10.8 to 18.1]), compared with the placebo group. Conclusions: This is the first U.S. study to describe the association between household PM and cardiac autonomic function among individuals with COPD, as well as the potential cardiovascular health benefits of household air cleaners." @default.
- W4307347845 created "2022-10-31" @default.
- W4307347845 creator A5000221548 @default.
- W4307347845 creator A5000991941 @default.
- W4307347845 creator A5003360183 @default.
- W4307347845 creator A5004605368 @default.
- W4307347845 creator A5012152640 @default.
- W4307347845 creator A5023824672 @default.
- W4307347845 creator A5023983175 @default.
- W4307347845 creator A5029130433 @default.
- W4307347845 creator A5033720138 @default.
- W4307347845 creator A5049120021 @default.
- W4307347845 creator A5059306478 @default.
- W4307347845 creator A5060026327 @default.
- W4307347845 creator A5069855798 @default.
- W4307347845 creator A5075789370 @default.
- W4307347845 date "2023-03-15" @default.
- W4307347845 modified "2023-10-17" @default.
- W4307347845 title "Indoor Air Pollution and Impaired Cardiac Autonomic Function in Chronic Obstructive Pulmonary Disease" @default.
- W4307347845 cites W1975124652 @default.
- W4307347845 cites W1980003405 @default.
- W4307347845 cites W1996758865 @default.
- W4307347845 cites W1999383461 @default.
- W4307347845 cites W2009751333 @default.
- W4307347845 cites W2010264557 @default.
- W4307347845 cites W2011876371 @default.
- W4307347845 cites W2028960923 @default.
- W4307347845 cites W2072187367 @default.
- W4307347845 cites W2073565501 @default.
- W4307347845 cites W2076386730 @default.
- W4307347845 cites W2083113471 @default.
- W4307347845 cites W2087697351 @default.
- W4307347845 cites W2098189516 @default.
- W4307347845 cites W2100658531 @default.
- W4307347845 cites W2107081835 @default.
- W4307347845 cites W2118951447 @default.
- W4307347845 cites W2120618124 @default.
- W4307347845 cites W2130097727 @default.
- W4307347845 cites W2142262297 @default.
- W4307347845 cites W2142483243 @default.
- W4307347845 cites W2148432391 @default.
- W4307347845 cites W2158882007 @default.
- W4307347845 cites W2159763911 @default.
- W4307347845 cites W2171606444 @default.
- W4307347845 cites W2178104551 @default.
- W4307347845 cites W2285072859 @default.
- W4307347845 cites W2293685484 @default.
- W4307347845 cites W2312864567 @default.
- W4307347845 cites W2340657858 @default.
- W4307347845 cites W2343819779 @default.
- W4307347845 cites W2418994609 @default.
- W4307347845 cites W2537881635 @default.
- W4307347845 cites W2614242365 @default.
- W4307347845 cites W2753051611 @default.
- W4307347845 cites W2789802763 @default.
- W4307347845 cites W2793915883 @default.
- W4307347845 cites W2801203881 @default.
- W4307347845 cites W2888098031 @default.
- W4307347845 cites W2919215848 @default.
- W4307347845 cites W3099363865 @default.
- W4307347845 cites W3110141071 @default.
- W4307347845 cites W3113117100 @default.
- W4307347845 cites W3119830189 @default.
- W4307347845 cites W3147178047 @default.
- W4307347845 cites W3194555754 @default.
- W4307347845 cites W3212981900 @default.
- W4307347845 cites W4223449366 @default.
- W4307347845 cites W4298441315 @default.
- W4307347845 doi "https://doi.org/10.1164/rccm.202203-0523oc" @default.
- W4307347845 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36288428" @default.
- W4307347845 hasPublicationYear "2023" @default.
- W4307347845 type Work @default.
- W4307347845 citedByCount "6" @default.
- W4307347845 countsByYear W43073478452023 @default.
- W4307347845 crossrefType "journal-article" @default.
- W4307347845 hasAuthorship W4307347845A5000221548 @default.
- W4307347845 hasAuthorship W4307347845A5000991941 @default.
- W4307347845 hasAuthorship W4307347845A5003360183 @default.
- W4307347845 hasAuthorship W4307347845A5004605368 @default.
- W4307347845 hasAuthorship W4307347845A5012152640 @default.
- W4307347845 hasAuthorship W4307347845A5023824672 @default.
- W4307347845 hasAuthorship W4307347845A5023983175 @default.
- W4307347845 hasAuthorship W4307347845A5029130433 @default.
- W4307347845 hasAuthorship W4307347845A5033720138 @default.
- W4307347845 hasAuthorship W4307347845A5049120021 @default.
- W4307347845 hasAuthorship W4307347845A5059306478 @default.
- W4307347845 hasAuthorship W4307347845A5060026327 @default.
- W4307347845 hasAuthorship W4307347845A5069855798 @default.
- W4307347845 hasAuthorship W4307347845A5075789370 @default.
- W4307347845 hasConcept C126322002 @default.
- W4307347845 hasConcept C164705383 @default.
- W4307347845 hasConcept C168563851 @default.
- W4307347845 hasConcept C1862650 @default.
- W4307347845 hasConcept C2776780178 @default.
- W4307347845 hasConcept C2777953023 @default.
- W4307347845 hasConcept C44249647 @default.
- W4307347845 hasConcept C71635504 @default.
- W4307347845 hasConcept C71924100 @default.