Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307352671> ?p ?o ?g. }
- W4307352671 endingPage "336" @default.
- W4307352671 startingPage "321" @default.
- W4307352671 abstract "Short tandem repeats (STRs) are units of 1-6 bp that repeat in a tandem fashion in DNA. Along with single nucleotide polymorphisms and large structural variations, they are among the major genomic variants underlying genetic, and likely phenotypic, divergence. STRs experience mutation rates that are orders of magnitude higher than other well-studied genotypic variants. Frequent copy number changes result in a wide range of alleles, and provide unique opportunities for modulating complex phenotypes through variation in repeat length. While classical studies have identified key roles of individual STR loci, the advent of improved sequencing technology, high-quality genome assemblies for diverse species, and bioinformatics methods for genome-wide STR analysis now enable more systematic study of STR variation across wide evolutionary ranges. In this review, we explore mutation and selection processes that affect STR copy number evolution, and how these processes give rise to varying STR patterns both within and across species. Finally, we review recent examples of functional and adaptive changes linked to STRs." @default.
- W4307352671 created "2022-10-31" @default.
- W4307352671 creator A5014282347 @default.
- W4307352671 creator A5029926674 @default.
- W4307352671 creator A5046692009 @default.
- W4307352671 creator A5053169737 @default.
- W4307352671 creator A5065055599 @default.
- W4307352671 creator A5070660191 @default.
- W4307352671 date "2022-10-26" @default.
- W4307352671 modified "2023-10-01" @default.
- W4307352671 title "Mutation and selection processes regulating short tandem repeats give rise to genetic and phenotypic diversity across species" @default.
- W4307352671 cites W126679084 @default.
- W4307352671 cites W1499198785 @default.
- W4307352671 cites W1504535992 @default.
- W4307352671 cites W1627352199 @default.
- W4307352671 cites W1653978584 @default.
- W4307352671 cites W1771404712 @default.
- W4307352671 cites W1851718497 @default.
- W4307352671 cites W1885698216 @default.
- W4307352671 cites W1892403210 @default.
- W4307352671 cites W1895398290 @default.
- W4307352671 cites W1945353891 @default.
- W4307352671 cites W1965321123 @default.
- W4307352671 cites W1965778443 @default.
- W4307352671 cites W1970114035 @default.
- W4307352671 cites W1970806530 @default.
- W4307352671 cites W1971516612 @default.
- W4307352671 cites W1977278056 @default.
- W4307352671 cites W1979146469 @default.
- W4307352671 cites W1980973068 @default.
- W4307352671 cites W1986769472 @default.
- W4307352671 cites W1997352668 @default.
- W4307352671 cites W2003398699 @default.
- W4307352671 cites W2004432131 @default.
- W4307352671 cites W2005157157 @default.
- W4307352671 cites W2006594317 @default.
- W4307352671 cites W2018816409 @default.
- W4307352671 cites W2025202959 @default.
- W4307352671 cites W2025366879 @default.
- W4307352671 cites W2026575204 @default.
- W4307352671 cites W2027899965 @default.
- W4307352671 cites W2043257091 @default.
- W4307352671 cites W2044222998 @default.
- W4307352671 cites W2044828847 @default.
- W4307352671 cites W2045035622 @default.
- W4307352671 cites W2057715520 @default.
- W4307352671 cites W2058598374 @default.
- W4307352671 cites W2066317159 @default.
- W4307352671 cites W2068906373 @default.
- W4307352671 cites W2069849645 @default.
- W4307352671 cites W2073212579 @default.
- W4307352671 cites W2079993886 @default.
- W4307352671 cites W2080447877 @default.
- W4307352671 cites W2080892263 @default.
- W4307352671 cites W2086795707 @default.
- W4307352671 cites W2093744222 @default.
- W4307352671 cites W2096118301 @default.
- W4307352671 cites W2096731080 @default.
- W4307352671 cites W2097095628 @default.
- W4307352671 cites W2097838377 @default.
- W4307352671 cites W2098914548 @default.
- W4307352671 cites W2102406302 @default.
- W4307352671 cites W2102701612 @default.
- W4307352671 cites W2105029364 @default.
- W4307352671 cites W2106811293 @default.
- W4307352671 cites W2111826500 @default.
- W4307352671 cites W2112066577 @default.
- W4307352671 cites W2112421940 @default.
- W4307352671 cites W2112814753 @default.
- W4307352671 cites W2114161957 @default.
- W4307352671 cites W2117065332 @default.
- W4307352671 cites W2124420957 @default.
- W4307352671 cites W2124561138 @default.
- W4307352671 cites W2128016314 @default.
- W4307352671 cites W2129905718 @default.
- W4307352671 cites W2131426370 @default.
- W4307352671 cites W2132297696 @default.
- W4307352671 cites W2139739374 @default.
- W4307352671 cites W2141042406 @default.
- W4307352671 cites W2143357905 @default.
- W4307352671 cites W2149459456 @default.
- W4307352671 cites W2149588035 @default.
- W4307352671 cites W2149789526 @default.
- W4307352671 cites W2155011204 @default.
- W4307352671 cites W2156327459 @default.
- W4307352671 cites W2156605247 @default.
- W4307352671 cites W2159163649 @default.
- W4307352671 cites W2160311988 @default.
- W4307352671 cites W2163255170 @default.
- W4307352671 cites W2170574599 @default.
- W4307352671 cites W2170600903 @default.
- W4307352671 cites W2227356030 @default.
- W4307352671 cites W2295580050 @default.
- W4307352671 cites W2319761515 @default.
- W4307352671 cites W2330659059 @default.
- W4307352671 cites W2396849069 @default.
- W4307352671 cites W2510383945 @default.
- W4307352671 cites W2529308344 @default.