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- W4307495890 abstract "An efficient Pd catalyzed cross-coupling method for 5-bromo-1,2,3-triazine is described. Optimization of the reaction conditions allowed for the preparation of a representative scope of (hetero)aryl-1,2,3-triazines (20 examples, up to 97% yield). The reaction scope was evaluated using a data science enabled boronic acid chemical space to assess the generality of the method. Additionally, diversification of the resulting products enabled the preparation of pyrimidines and pyridines in yields of up to 80% and in only two steps." @default.
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- W4307495890 date "2022-10-28" @default.
- W4307495890 modified "2023-09-26" @default.
- W4307495890 title "Cross-Coupling Reactions of 5-Bromo-1,2,3-triazine" @default.
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- W4307495890 doi "https://doi.org/10.1021/acs.joc.2c02082" @default.
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