Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307505941> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4307505941 endingPage "352" @default.
- W4307505941 startingPage "345" @default.
- W4307505941 abstract "Cirrhosis is an advanced stage of liver fibrosis that can be caused by many factors, including: chronic alcoholism, chronic exposure to environmental chemicals and viral disease. No matter the cause, liver cirrhosis is oxidative stress-mediated. Alcohol metabolism in the liver is related to ROS production, mitochondrial injury and steatosis. Steatosis, the first step in alcoholic liver disease is caused by alcohol consumption. Heavy continued alcohol consumption leads to progression of alcoholic liver disease to hepatitis, fibrosis and ultimately to cirrhosis. Metabolism of alcohol occurs via initial oxidation to acetaldehyde and ultimately to acetate via free radical-mediated mechanisms. Metabolism of environmental chemicals in the liver also proceeds via oxidative stress related mechanisms. Hepatitis C, a viral disease, is also a cause of liver cirrhosis. The connection between Hepatitis C and oxidative stress is mechanistically related to reduced antioxidant functioning in the liver caused by the virus." @default.
- W4307505941 created "2022-11-02" @default.
- W4307505941 creator A5008520278 @default.
- W4307505941 date "2023-01-01" @default.
- W4307505941 modified "2023-09-23" @default.
- W4307505941 title "Liver cirrhosis" @default.
- W4307505941 cites W1910177016 @default.
- W4307505941 cites W1971884054 @default.
- W4307505941 cites W1972706158 @default.
- W4307505941 cites W1980033214 @default.
- W4307505941 cites W2007230336 @default.
- W4307505941 cites W2023195072 @default.
- W4307505941 cites W2023503151 @default.
- W4307505941 cites W2040588477 @default.
- W4307505941 cites W2053326488 @default.
- W4307505941 cites W2068084277 @default.
- W4307505941 cites W2073976519 @default.
- W4307505941 cites W2097779819 @default.
- W4307505941 cites W2112144522 @default.
- W4307505941 cites W2137322585 @default.
- W4307505941 cites W2152932294 @default.
- W4307505941 cites W2161571451 @default.
- W4307505941 cites W2253523184 @default.
- W4307505941 cites W2315690141 @default.
- W4307505941 cites W2767233641 @default.
- W4307505941 cites W3021836237 @default.
- W4307505941 cites W4211260107 @default.
- W4307505941 cites W4246235415 @default.
- W4307505941 cites W4247878364 @default.
- W4307505941 doi "https://doi.org/10.1016/b978-0-323-91890-9.00003-9" @default.
- W4307505941 hasPublicationYear "2023" @default.
- W4307505941 type Work @default.
- W4307505941 citedByCount "0" @default.
- W4307505941 crossrefType "book-chapter" @default.
- W4307505941 hasAuthorship W4307505941A5008520278 @default.
- W4307505941 hasConcept C126322002 @default.
- W4307505941 hasConcept C2777214474 @default.
- W4307505941 hasConcept C71924100 @default.
- W4307505941 hasConcept C90924648 @default.
- W4307505941 hasConceptScore W4307505941C126322002 @default.
- W4307505941 hasConceptScore W4307505941C2777214474 @default.
- W4307505941 hasConceptScore W4307505941C71924100 @default.
- W4307505941 hasConceptScore W4307505941C90924648 @default.
- W4307505941 hasLocation W43075059411 @default.
- W4307505941 hasOpenAccess W4307505941 @default.
- W4307505941 hasPrimaryLocation W43075059411 @default.
- W4307505941 hasRelatedWork W2364009260 @default.
- W4307505941 hasRelatedWork W2380057670 @default.
- W4307505941 hasRelatedWork W2381699712 @default.
- W4307505941 hasRelatedWork W2385697996 @default.
- W4307505941 hasRelatedWork W2391160944 @default.
- W4307505941 hasRelatedWork W2391842199 @default.
- W4307505941 hasRelatedWork W2896627865 @default.
- W4307505941 hasRelatedWork W3091367366 @default.
- W4307505941 hasRelatedWork W4234155861 @default.
- W4307505941 hasRelatedWork W2501299524 @default.
- W4307505941 isParatext "false" @default.
- W4307505941 isRetracted "false" @default.
- W4307505941 workType "book-chapter" @default.