Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307543230> ?p ?o ?g. }
- W4307543230 endingPage "78" @default.
- W4307543230 startingPage "71" @default.
- W4307543230 abstract "Mortality and disability rates in spontaneous intracranial hemorrhages remain high despite medical advances. In recent decades, much attention has been paid to neuroinflammation as a typical response to brain damage. Inflammation plays an important role in the acute and chronic phases of the disease. The relationship between plasma and cerebrospinal fluid cytokines, as well as the factors affecting their ratios, is currently not completely clear. The objective was to study the inflammatory response to spontaneous intracranial hemorrhage. Subjects and Methods. 59 patients aged 18 to 72 years (48 ± 6) were enrolled in the study. Patients were admitted to the intensive care unit after an episode of spontaneous intracranial hemorrhage. The levels of interleukins in blood plasma were studied: 6, 8, 10, TNF-α, C-reactive protein, blood leukocytes, and procalcitonin (by a semi-quantitative method). In the cerebrospinal fluid, the following parameters were evaluated: cytosis, protein, glucose, lactate, cytokines (6, 8, 10, TNF-α). Blood samples were collected on days 1, 2, 3, 5, 7, 9, 14, 21, 28, 35, and 45. Results. Systemic inflammatory response developed in all patients from the first day of acute brain injury. The most significant response was formed by glial brain cells which was confirmed by high levels of cytokines in the cerebrospinal fluid, hundreds and thousands of times higher than blood levels of cytokines. Conclusion. Levels of pro-inflammatory cytokines are predictors of an unfavorable outcome." @default.
- W4307543230 created "2022-11-03" @default.
- W4307543230 creator A5011635826 @default.
- W4307543230 creator A5021761935 @default.
- W4307543230 creator A5023165290 @default.
- W4307543230 creator A5032474372 @default.
- W4307543230 creator A5037653610 @default.
- W4307543230 creator A5052512343 @default.
- W4307543230 creator A5058737159 @default.
- W4307543230 creator A5076989224 @default.
- W4307543230 date "2022-10-29" @default.
- W4307543230 modified "2023-10-05" @default.
- W4307543230 title "Inflammatory Response in Patients with Spontaneous Intracranial Hemorrhages" @default.
- W4307543230 cites W1883357276 @default.
- W4307543230 cites W2009065888 @default.
- W4307543230 cites W2018079705 @default.
- W4307543230 cites W2018683277 @default.
- W4307543230 cites W2038344988 @default.
- W4307543230 cites W2051813950 @default.
- W4307543230 cites W2054263900 @default.
- W4307543230 cites W2057831907 @default.
- W4307543230 cites W2065132110 @default.
- W4307543230 cites W2070151075 @default.
- W4307543230 cites W2083838049 @default.
- W4307543230 cites W2088561357 @default.
- W4307543230 cites W2089810254 @default.
- W4307543230 cites W2094785614 @default.
- W4307543230 cites W2125264782 @default.
- W4307543230 cites W2132276423 @default.
- W4307543230 cites W2144507398 @default.
- W4307543230 cites W2146610973 @default.
- W4307543230 cites W2156097710 @default.
- W4307543230 cites W2158147889 @default.
- W4307543230 cites W2162023629 @default.
- W4307543230 cites W2166957333 @default.
- W4307543230 cites W2167183660 @default.
- W4307543230 cites W2181278247 @default.
- W4307543230 cites W2314523849 @default.
- W4307543230 cites W2337359323 @default.
- W4307543230 cites W2597210998 @default.
- W4307543230 cites W2613030232 @default.
- W4307543230 cites W2799386458 @default.
- W4307543230 cites W2898400365 @default.
- W4307543230 cites W2983425799 @default.
- W4307543230 doi "https://doi.org/10.21292/2078-5658-2022-19-5-71-78" @default.
- W4307543230 hasPublicationYear "2022" @default.
- W4307543230 type Work @default.
- W4307543230 citedByCount "0" @default.
- W4307543230 crossrefType "journal-article" @default.
- W4307543230 hasAuthorship W4307543230A5011635826 @default.
- W4307543230 hasAuthorship W4307543230A5021761935 @default.
- W4307543230 hasAuthorship W4307543230A5023165290 @default.
- W4307543230 hasAuthorship W4307543230A5032474372 @default.
- W4307543230 hasAuthorship W4307543230A5037653610 @default.
- W4307543230 hasAuthorship W4307543230A5052512343 @default.
- W4307543230 hasAuthorship W4307543230A5058737159 @default.
- W4307543230 hasAuthorship W4307543230A5076989224 @default.
- W4307543230 hasBestOaLocation W43075432301 @default.
- W4307543230 hasConcept C10936531 @default.
- W4307543230 hasConcept C126322002 @default.
- W4307543230 hasConcept C164027704 @default.
- W4307543230 hasConcept C17991360 @default.
- W4307543230 hasConcept C203014093 @default.
- W4307543230 hasConcept C2776252253 @default.
- W4307543230 hasConcept C2776914184 @default.
- W4307543230 hasConcept C2778384902 @default.
- W4307543230 hasConcept C2779651940 @default.
- W4307543230 hasConcept C2781090800 @default.
- W4307543230 hasConcept C2781195455 @default.
- W4307543230 hasConcept C3020196126 @default.
- W4307543230 hasConcept C71924100 @default.
- W4307543230 hasConcept C87753298 @default.
- W4307543230 hasConcept C90924648 @default.
- W4307543230 hasConceptScore W4307543230C10936531 @default.
- W4307543230 hasConceptScore W4307543230C126322002 @default.
- W4307543230 hasConceptScore W4307543230C164027704 @default.
- W4307543230 hasConceptScore W4307543230C17991360 @default.
- W4307543230 hasConceptScore W4307543230C203014093 @default.
- W4307543230 hasConceptScore W4307543230C2776252253 @default.
- W4307543230 hasConceptScore W4307543230C2776914184 @default.
- W4307543230 hasConceptScore W4307543230C2778384902 @default.
- W4307543230 hasConceptScore W4307543230C2779651940 @default.
- W4307543230 hasConceptScore W4307543230C2781090800 @default.
- W4307543230 hasConceptScore W4307543230C2781195455 @default.
- W4307543230 hasConceptScore W4307543230C3020196126 @default.
- W4307543230 hasConceptScore W4307543230C71924100 @default.
- W4307543230 hasConceptScore W4307543230C87753298 @default.
- W4307543230 hasConceptScore W4307543230C90924648 @default.
- W4307543230 hasIssue "5" @default.
- W4307543230 hasLocation W43075432301 @default.
- W4307543230 hasOpenAccess W4307543230 @default.
- W4307543230 hasPrimaryLocation W43075432301 @default.
- W4307543230 hasRelatedWork W2038002081 @default.
- W4307543230 hasRelatedWork W2051016129 @default.
- W4307543230 hasRelatedWork W2163978788 @default.
- W4307543230 hasRelatedWork W2171331691 @default.
- W4307543230 hasRelatedWork W2314597305 @default.
- W4307543230 hasRelatedWork W2461161308 @default.