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• W4307647285 abstract "Diffusion MRI plays an important role in clinical MRI and neuroscience. The fact that the method is designed to probe the microscopic motion of water molecules undergoing diffusion also makes it inherently sensitive to macroscopic motion by subjects and anatomical organs. This chapter reviews the development of diffusion MRI with a focus on the challenges presented by its particular sensitivity to motion and the methods that have been introduced to address this limitation. Both short- and long-term motion have a detrimental effect on image quality in diffusion imaging. Short-term subject motion during the diffusion preparation results in phase errors that vary between spin excitations and cause severe image artifacts with multishot sequences. These effects can be mitigated by using single-shot sequences or multishot methods with phase navigators. Long-term subject motion during the acquisition of a diffusion MRI time series causes poor registration between individual diffusion-weighted images, which introduces quantitative errors in the estimation of diffusion parameters. Correcting for long-term subject motion in diffusion MRI is especially difficult due to the strong variation in contrast from image to image, caused by the changing diffusion gradient directions and amplitudes between successive time points. A variety of methods have been proposed to correct for these long-term motion effects, including reacquisition schemes, navigator scans, and prospective motion-correction procedures that compensate for movement in real time during the scan. Together with motion prevention, retrospective motion correction and scan acceleration strategies, the techniques described this chapter have led to a continuous improvement in the quality of diffusion-weighted images and in the reliability of quantitative diffusion parameter estimates." @default.
• W4307647285 created "2022-11-04" @default.
• W4307647285 creator A5038274720 @default.
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• W4307647285 date "2022-01-01" @default.
• W4307647285 modified "2023-10-12" @default.
• W4307647285 title "Diffusion imaging" @default.
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• W4307647285 doi "https://doi.org/10.1016/b978-0-12-824460-9.00032-7" @default.
• W4307647285 hasPublicationYear "2022" @default.
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