Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307723786> ?p ?o ?g. }
- W4307723786 endingPage "106686" @default.
- W4307723786 startingPage "106686" @default.
- W4307723786 abstract "Dual resistance to linezolid and glycopeptides is a milestone reached by certain extensively drug-resistant (XDR) enterococci. This paper describes the molecular and epidemiological investigations of a linezolid-resistant and vancomycin-resistant Enterococcus faecium (E. faecium) (LVREf) outbreak in the French overseas territory of Reunion Island (Indian Ocean).All vancomycin-resistant Enterococcus (VRE) isolates detected on Reunion Island between 2015 and 2019 were included in the study. The VRE isolates were phenotypically characterised and genetically explored by whole-genome sequencing (WGS).Sixteen vancomycin-resistant E. faecium (VREf) isolates were retrieved between 2015 and 2019. Seven isolates obtained in 2019 were involved in the outbreak. These seven LVREf isolates from the 2019 outbreak at the University Hospital of Reunion Island (UHRI) were suspected to be related to a linezolid-susceptible VREf strain imported from India. An epidemiological link was highlighted for six of the seven outbreak cases. All the LVREf outbreak isolates were obtained from rectal swabs (colonisation) and resistant to vancomycin (MIC > 128 mg/L) and linezolid (MIC 8-32 mg/L); one isolate was also resistant to daptomycin (MIC 8 mg/L). The seven outbreak isolates were positive for the vanA and optrA genes and belonged to ST761.These results argue for the strict application of control and prevention measures for VRE clones at high risk of spread, particularly in areas such as Reunion Island where the risk of importation from the Indian subcontinent is high. The regional spread of optrA linezolid-resistance genes in VRE isolates is a matter of concern, due to possibility of treatment failure." @default.
- W4307723786 created "2022-11-05" @default.
- W4307723786 creator A5001940568 @default.
- W4307723786 creator A5007052582 @default.
- W4307723786 creator A5009840704 @default.
- W4307723786 creator A5011253485 @default.
- W4307723786 creator A5012804618 @default.
- W4307723786 creator A5014771225 @default.
- W4307723786 creator A5021526802 @default.
- W4307723786 creator A5039438736 @default.
- W4307723786 creator A5041749912 @default.
- W4307723786 creator A5058454501 @default.
- W4307723786 creator A5065822723 @default.
- W4307723786 creator A5068877037 @default.
- W4307723786 creator A5077976255 @default.
- W4307723786 creator A5081292184 @default.
- W4307723786 creator A5086636704 @default.
- W4307723786 creator A5086828609 @default.
- W4307723786 date "2022-11-01" @default.
- W4307723786 modified "2023-09-25" @default.
- W4307723786 title "Investigation of a vanA linezolid- and vancomycin-resistant Enterococcus faecium outbreak in the Southwest Indian Ocean (Reunion Island)" @default.
- W4307723786 cites W1508893821 @default.
- W4307723786 cites W1565682406 @default.
- W4307723786 cites W1835494231 @default.
- W4307723786 cites W1976667730 @default.
- W4307723786 cites W2041932561 @default.
- W4307723786 cites W2062320986 @default.
- W4307723786 cites W2091807493 @default.
- W4307723786 cites W2120902911 @default.
- W4307723786 cites W2142343447 @default.
- W4307723786 cites W2168413372 @default.
- W4307723786 cites W2396031127 @default.
- W4307723786 cites W2410074864 @default.
- W4307723786 cites W2522178814 @default.
- W4307723786 cites W2523739625 @default.
- W4307723786 cites W2538870813 @default.
- W4307723786 cites W2920984376 @default.
- W4307723786 cites W2921622580 @default.
- W4307723786 cites W2923864184 @default.
- W4307723786 cites W2995326355 @default.
- W4307723786 cites W3011319265 @default.
- W4307723786 cites W3026254152 @default.
- W4307723786 cites W3033489301 @default.
- W4307723786 cites W3048398081 @default.
- W4307723786 cites W3091480465 @default.
- W4307723786 cites W3097464624 @default.
- W4307723786 cites W3097921880 @default.
- W4307723786 cites W3107627524 @default.
- W4307723786 cites W3156458251 @default.
- W4307723786 cites W3159371609 @default.
- W4307723786 cites W3159909751 @default.
- W4307723786 cites W3165724519 @default.
- W4307723786 cites W3184193161 @default.
- W4307723786 doi "https://doi.org/10.1016/j.ijantimicag.2022.106686" @default.
- W4307723786 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36503708" @default.
- W4307723786 hasPublicationYear "2022" @default.
- W4307723786 type Work @default.
- W4307723786 citedByCount "2" @default.
- W4307723786 countsByYear W43077237862023 @default.
- W4307723786 crossrefType "journal-article" @default.
- W4307723786 hasAuthorship W4307723786A5001940568 @default.
- W4307723786 hasAuthorship W4307723786A5007052582 @default.
- W4307723786 hasAuthorship W4307723786A5009840704 @default.
- W4307723786 hasAuthorship W4307723786A5011253485 @default.
- W4307723786 hasAuthorship W4307723786A5012804618 @default.
- W4307723786 hasAuthorship W4307723786A5014771225 @default.
- W4307723786 hasAuthorship W4307723786A5021526802 @default.
- W4307723786 hasAuthorship W4307723786A5039438736 @default.
- W4307723786 hasAuthorship W4307723786A5041749912 @default.
- W4307723786 hasAuthorship W4307723786A5058454501 @default.
- W4307723786 hasAuthorship W4307723786A5065822723 @default.
- W4307723786 hasAuthorship W4307723786A5068877037 @default.
- W4307723786 hasAuthorship W4307723786A5077976255 @default.
- W4307723786 hasAuthorship W4307723786A5081292184 @default.
- W4307723786 hasAuthorship W4307723786A5086636704 @default.
- W4307723786 hasAuthorship W4307723786A5086828609 @default.
- W4307723786 hasBestOaLocation W43077237861 @default.
- W4307723786 hasConcept C104317684 @default.
- W4307723786 hasConcept C116675565 @default.
- W4307723786 hasConcept C135763542 @default.
- W4307723786 hasConcept C159047783 @default.
- W4307723786 hasConcept C2777677444 @default.
- W4307723786 hasConcept C2778980435 @default.
- W4307723786 hasConcept C2779489039 @default.
- W4307723786 hasConcept C2780585763 @default.
- W4307723786 hasConcept C2781414143 @default.
- W4307723786 hasConcept C501593827 @default.
- W4307723786 hasConcept C523546767 @default.
- W4307723786 hasConcept C54355233 @default.
- W4307723786 hasConcept C86803240 @default.
- W4307723786 hasConcept C89423630 @default.
- W4307723786 hasConcept C97669555 @default.
- W4307723786 hasConceptScore W4307723786C104317684 @default.
- W4307723786 hasConceptScore W4307723786C116675565 @default.
- W4307723786 hasConceptScore W4307723786C135763542 @default.
- W4307723786 hasConceptScore W4307723786C159047783 @default.
- W4307723786 hasConceptScore W4307723786C2777677444 @default.
- W4307723786 hasConceptScore W4307723786C2778980435 @default.