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- W4307756464 abstract "Abstract Peri-implant infection remains one of the greatest threats to orthopedics. The construction of bone implants with good antibacterial and osteogenic properties is beneficial for reducing the risk of implant-related infections and healing bone defects. In this study, N-halamine coating (namely N–Cl) was grafted onto alkali-heat treated titanium (Ti) using polydopamine to endow Ti-based orthopedic implants with strong bactericidal activity. Surface characterization revealed that the N–Cl coating has porous structure loaded with active chlorine (Cl + ). The N–Cl coating also provided micro/nano-structured Ti surfaces with excellent antibacterial ability via transformation between N–H and N–Cl, and approximately 100% disinfection was achieved. Furthermore, the as-prepared N–Cl coating exhibited good biocompatibility and osteogenesis ability in vitro . These results indicate that applying N–Cl coatings on Ti could prevent and treat peri-implant infections." @default.
- W4307756464 created "2022-11-05" @default.
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- W4307756464 date "2022-11-15" @default.
- W4307756464 modified "2023-09-30" @default.
- W4307756464 title "Surface modification of titanium with antibacterial porous N-halamine coating to prevent peri-implant infection" @default.
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- W4307756464 doi "https://doi.org/10.1088/1748-605x/ac9e33" @default.
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