Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307776641> ?p ?o ?g. }
- W4307776641 abstract "Neurons receive information through their synaptic inputs, but the functional significance of how those inputs are mapped on to a cell's dendrites remains unclear. We studied this question in a grasshopper visual neuron that tracks approaching objects and triggers escape behavior before an impending collision. In response to black approaching objects, the neuron receives OFF excitatory inputs that form a retinotopic map of the visual field onto compartmentalized, distal dendrites. Subsequent processing of these OFF inputs by active membrane conductances allows the neuron to discriminate the spatial coherence of such stimuli. In contrast, we show that ON excitatory synaptic inputs activated by white approaching objects map in a random manner onto a more proximal dendritic field of the same neuron. The lack of retinotopic synaptic arrangement results in the neuron's inability to discriminate the coherence of white approaching stimuli. Yet, the neuron retains the ability to discriminate stimulus coherence for checkered stimuli of mixed ON/OFF polarity. The coarser mapping and processing of ON stimuli thus has a minimal impact, while reducing the total energetic cost of the circuit. Further, we show that these differences in ON/OFF neuronal processing are behaviorally relevant, being tightly correlated with the animal's escape behavior to light and dark stimuli of variable coherence. Our results show that the synaptic mapping of excitatory inputs affects the fine stimulus discrimination ability of single neurons and document the resulting functional impact on behavior." @default.
- W4307776641 created "2022-11-05" @default.
- W4307776641 creator A5020889871 @default.
- W4307776641 creator A5026337102 @default.
- W4307776641 creator A5029869778 @default.
- W4307776641 creator A5050733730 @default.
- W4307776641 creator A5070459237 @default.
- W4307776641 date "2022-10-31" @default.
- W4307776641 modified "2023-10-18" @default.
- W4307776641 title "Contrast polarity-specific mapping improves efficiency of neuronal computation for collision detection" @default.
- W4307776641 cites W1919609383 @default.
- W4307776641 cites W1922045244 @default.
- W4307776641 cites W1967324141 @default.
- W4307776641 cites W1984478493 @default.
- W4307776641 cites W1984736547 @default.
- W4307776641 cites W1991472850 @default.
- W4307776641 cites W1995542880 @default.
- W4307776641 cites W2020134397 @default.
- W4307776641 cites W2022095435 @default.
- W4307776641 cites W2023874864 @default.
- W4307776641 cites W2025318220 @default.
- W4307776641 cites W2027968420 @default.
- W4307776641 cites W2029740022 @default.
- W4307776641 cites W2032167415 @default.
- W4307776641 cites W2037084455 @default.
- W4307776641 cites W2039459343 @default.
- W4307776641 cites W2042422091 @default.
- W4307776641 cites W2042974695 @default.
- W4307776641 cites W2044896442 @default.
- W4307776641 cites W2053268711 @default.
- W4307776641 cites W2062989488 @default.
- W4307776641 cites W2074421072 @default.
- W4307776641 cites W2078340953 @default.
- W4307776641 cites W2092581899 @default.
- W4307776641 cites W2106069155 @default.
- W4307776641 cites W2121659143 @default.
- W4307776641 cites W2129036096 @default.
- W4307776641 cites W2132148741 @default.
- W4307776641 cites W2133741176 @default.
- W4307776641 cites W2140242630 @default.
- W4307776641 cites W2144118163 @default.
- W4307776641 cites W2144588131 @default.
- W4307776641 cites W2151035455 @default.
- W4307776641 cites W2152781875 @default.
- W4307776641 cites W2164189343 @default.
- W4307776641 cites W2256813687 @default.
- W4307776641 cites W2267456908 @default.
- W4307776641 cites W2302230753 @default.
- W4307776641 cites W2309827256 @default.
- W4307776641 cites W2414343162 @default.
- W4307776641 cites W2498780836 @default.
- W4307776641 cites W2521862911 @default.
- W4307776641 cites W2533977883 @default.
- W4307776641 cites W2534688682 @default.
- W4307776641 cites W2571918371 @default.
- W4307776641 cites W2605403086 @default.
- W4307776641 cites W2763282685 @default.
- W4307776641 cites W2768029819 @default.
- W4307776641 cites W2800459101 @default.
- W4307776641 cites W2803982628 @default.
- W4307776641 cites W2866029803 @default.
- W4307776641 cites W2919901116 @default.
- W4307776641 cites W2948382558 @default.
- W4307776641 cites W2950487702 @default.
- W4307776641 cites W2951699712 @default.
- W4307776641 cites W2953712016 @default.
- W4307776641 cites W2981051561 @default.
- W4307776641 cites W3003288794 @default.
- W4307776641 cites W3014104609 @default.
- W4307776641 cites W3022915132 @default.
- W4307776641 cites W3138514668 @default.
- W4307776641 cites W3186871256 @default.
- W4307776641 cites W3203411182 @default.
- W4307776641 cites W4212952892 @default.
- W4307776641 cites W4220795574 @default.
- W4307776641 cites W4221123062 @default.
- W4307776641 cites W4307776641 @default.
- W4307776641 doi "https://doi.org/10.7554/elife.79772" @default.
- W4307776641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36314775" @default.
- W4307776641 hasPublicationYear "2022" @default.
- W4307776641 type Work @default.
- W4307776641 citedByCount "1" @default.
- W4307776641 countsByYear W43077766412022 @default.
- W4307776641 crossrefType "journal-article" @default.
- W4307776641 hasAuthorship W4307776641A5020889871 @default.
- W4307776641 hasAuthorship W4307776641A5026337102 @default.
- W4307776641 hasAuthorship W4307776641A5029869778 @default.
- W4307776641 hasAuthorship W4307776641A5050733730 @default.
- W4307776641 hasAuthorship W4307776641A5070459237 @default.
- W4307776641 hasBestOaLocation W43077766411 @default.
- W4307776641 hasConcept C112592302 @default.
- W4307776641 hasConcept C15744967 @default.
- W4307776641 hasConcept C169760540 @default.
- W4307776641 hasConcept C17077164 @default.
- W4307776641 hasConcept C2778794669 @default.
- W4307776641 hasConcept C2779918689 @default.
- W4307776641 hasConcept C41008148 @default.
- W4307776641 hasConcept C542102704 @default.
- W4307776641 hasConcept C86803240 @default.
- W4307776641 hasConceptScore W4307776641C112592302 @default.