Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307777235> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4307777235 endingPage "118" @default.
- W4307777235 startingPage "109" @default.
- W4307777235 abstract "We examined the effects of fixe-dose combinations (FDCs) versus loose-dose combinations (LDCs) on costs from the payer and patient perspective and investigated potential channels contributing to differences in costs between the two modes of treatment.We investigated administrative data from 2017 to 2020 on diabetes patients in Germany. After using prospensity-score matching to remove dissimilarities between FDC and LDC patients, we compared changes in costs with a difference-in-differences approach. We analyzed pharmaceutical costs, inpatient and outpatient costs, other costs and total healthcare costs from the payer perspective, and co-payments from the patient perspective.The sample comprised 1117 FDC and 1272 LDC patients. Regression analysis revealed that FDC therapy significantly increased antidiabetic pharmaceutical spending in the first year by 5.5% (p < 0.01), but decreased co-payments by 33% (p < 0.01) in the first and 44% (p < 0.01) in the second year. We also observed a trend towards higher outpatient spending in the first year. No significant differences were found with respect to inpatient or other costs. The increase in antidiabetic pharmaceutical spending did not contribute to a significant increase in total healthcare expenditure. We identified a shift of co-payments to the payer and higher adherence as possible mechanisms behind the increase in antidiabetic pharmaceutical spending.Although FDC therapy increased disease-specific pharmaceutical spending in the short term, this increase did not lead to differences in total healthcare costs from the payer perspective. From the patient perspective, FDC therapy may be the preferred treatment approach, because of significant saving in co-payments, which is likely attributable to the elimination of one co-payment and therefore a shift in costs to the payer." @default.
- W4307777235 created "2022-11-05" @default.
- W4307777235 creator A5023415012 @default.
- W4307777235 creator A5026986766 @default.
- W4307777235 creator A5054910144 @default.
- W4307777235 date "2022-10-31" @default.
- W4307777235 modified "2023-10-05" @default.
- W4307777235 title "Economic Effects of Fixed-Dose Versus Loose-Dose Combination Therapy for Type 2 Diabetes Patients" @default.
- W4307777235 cites W1521836421 @default.
- W4307777235 cites W1984035423 @default.
- W4307777235 cites W2057780602 @default.
- W4307777235 cites W2061818351 @default.
- W4307777235 cites W2062469203 @default.
- W4307777235 cites W2074328251 @default.
- W4307777235 cites W2088113192 @default.
- W4307777235 cites W2111635289 @default.
- W4307777235 cites W2129058494 @default.
- W4307777235 cites W2137665561 @default.
- W4307777235 cites W2148413264 @default.
- W4307777235 cites W2160704894 @default.
- W4307777235 cites W2165043532 @default.
- W4307777235 cites W2273894627 @default.
- W4307777235 cites W2279506649 @default.
- W4307777235 cites W2615424528 @default.
- W4307777235 cites W2910475517 @default.
- W4307777235 cites W2914192537 @default.
- W4307777235 cites W3007393873 @default.
- W4307777235 cites W3159035779 @default.
- W4307777235 doi "https://doi.org/10.1007/s40258-022-00760-x" @default.
- W4307777235 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36310297" @default.
- W4307777235 hasPublicationYear "2022" @default.
- W4307777235 type Work @default.
- W4307777235 citedByCount "0" @default.
- W4307777235 crossrefType "journal-article" @default.
- W4307777235 hasAuthorship W4307777235A5023415012 @default.
- W4307777235 hasAuthorship W4307777235A5026986766 @default.
- W4307777235 hasAuthorship W4307777235A5054910144 @default.
- W4307777235 hasBestOaLocation W43077772351 @default.
- W4307777235 hasConcept C10138342 @default.
- W4307777235 hasConcept C134018914 @default.
- W4307777235 hasConcept C137992405 @default.
- W4307777235 hasConcept C138816342 @default.
- W4307777235 hasConcept C144133560 @default.
- W4307777235 hasConcept C145097563 @default.
- W4307777235 hasConcept C159110408 @default.
- W4307777235 hasConcept C160735492 @default.
- W4307777235 hasConcept C162324750 @default.
- W4307777235 hasConcept C194828623 @default.
- W4307777235 hasConcept C2777180221 @default.
- W4307777235 hasConcept C50522688 @default.
- W4307777235 hasConcept C524218345 @default.
- W4307777235 hasConcept C555293320 @default.
- W4307777235 hasConcept C71924100 @default.
- W4307777235 hasConceptScore W4307777235C10138342 @default.
- W4307777235 hasConceptScore W4307777235C134018914 @default.
- W4307777235 hasConceptScore W4307777235C137992405 @default.
- W4307777235 hasConceptScore W4307777235C138816342 @default.
- W4307777235 hasConceptScore W4307777235C144133560 @default.
- W4307777235 hasConceptScore W4307777235C145097563 @default.
- W4307777235 hasConceptScore W4307777235C159110408 @default.
- W4307777235 hasConceptScore W4307777235C160735492 @default.
- W4307777235 hasConceptScore W4307777235C162324750 @default.
- W4307777235 hasConceptScore W4307777235C194828623 @default.
- W4307777235 hasConceptScore W4307777235C2777180221 @default.
- W4307777235 hasConceptScore W4307777235C50522688 @default.
- W4307777235 hasConceptScore W4307777235C524218345 @default.
- W4307777235 hasConceptScore W4307777235C555293320 @default.
- W4307777235 hasConceptScore W4307777235C71924100 @default.
- W4307777235 hasFunder F4320323381 @default.
- W4307777235 hasFunder F4320332999 @default.
- W4307777235 hasIssue "1" @default.
- W4307777235 hasLocation W43077772351 @default.
- W4307777235 hasLocation W43077772352 @default.
- W4307777235 hasLocation W43077772353 @default.
- W4307777235 hasOpenAccess W4307777235 @default.
- W4307777235 hasPrimaryLocation W43077772351 @default.
- W4307777235 hasRelatedWork W2001296149 @default.
- W4307777235 hasRelatedWork W2005753789 @default.
- W4307777235 hasRelatedWork W2058682722 @default.
- W4307777235 hasRelatedWork W2416980606 @default.
- W4307777235 hasRelatedWork W2592677275 @default.
- W4307777235 hasRelatedWork W2900798622 @default.
- W4307777235 hasRelatedWork W2995907519 @default.
- W4307777235 hasRelatedWork W3011308260 @default.
- W4307777235 hasRelatedWork W4245983263 @default.
- W4307777235 hasRelatedWork W4248412978 @default.
- W4307777235 hasVolume "21" @default.
- W4307777235 isParatext "false" @default.
- W4307777235 isRetracted "false" @default.
- W4307777235 workType "article" @default.