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- W4307777291 endingPage "20257" @default.
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- W4307777291 abstract "A nickel complex of isoquinox promoted enantioselective conjugate arylation and heteroarylation of enones using aryl and heteroaryl halides directly. The reaction was successfully applied to stereoselective syntheses of ar-turmerone, chiral fragments of (+)-tolterodine and AZD5672. Mechanistically, experiments and calculations supported that an arylnickel(I) complex inserted to enones via an elementary 1,4-addition." @default.
- W4307777291 created "2022-11-05" @default.
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- W4307777291 date "2022-10-31" @default.
- W4307777291 modified "2023-10-18" @default.
- W4307777291 title "Nickel-Catalyzed Enantioselective Reductive Conjugate Arylation and Heteroarylation via an Elementary Mechanism of 1,4-Addition" @default.
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- W4307777291 doi "https://doi.org/10.1021/jacs.2c05678" @default.
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