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• W4307777479 endingPage "8175" @default.
• W4307777479 startingPage "8170" @default.
• W4307777479 abstract "The introduction of sulfonyl fluoride groups into bioactive molecules can often bring about enhanced biological activity, which has attracted more research interest in chemical biology and drug development in recent years. Here, we report the development of a radical fluorosulfonylation of alkenes/intramolecular arylation cascade for the construction of chromanes with sulfonyl fluoride groups attached. The radical 1,2-fluorosulfonyl arylation reactions proceed well in both endo and exo cyclization fashions, allowing for further variation of the distance between the chromane core and the sulfonyl fluoride group." @default.
• W4307777479 created "2022-11-05" @default.
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• W4307777479 date "2022-10-31" @default.
• W4307777479 modified "2023-10-16" @default.
• W4307777479 title "Radical Fluorosulfonyl Arylation of Alkenes: Accessing FSO₂-Functionalized Chromanes via Formal Endo and Exo Cyclization" @default.
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• W4307777479 doi "https://doi.org/10.1021/acs.orglett.2c03224" @default.
• W4307777479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36315024" @default.
• W4307777479 hasPublicationYear "2022" @default.
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