Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307836700> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W4307836700 abstract "Background Definitive treatment of acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and myeloproliferative neoplasm (MPN) involves allogeneic hematopoietic stem cell transplantation (allo-HSCT), either with myeloablative (MAC) or reduced-intensity conditioning (RIC). These diseases may arise in patients with a prior solid tumor. The impact of antecedent solid tumor on transplantation decision-making and outcomes is not well defined. Methods The authors performed a retrospective cohort study to address this question. A total of 1193 patients who underwent allo-HSCT for AML, MDS, or MPN between January 1, 2010 and December 31, 2018 were included, 102 of whom had a history of prior solid tumor. Results Patients with prior solid tumor were older (median age, 62.5 vs. 54.9 years; p < .00001) and more frequently were conditioned with RIC (52.5% vs. 27.2%; p < .00001). A higher incidence of acute graft-versus-host disease was observed in patients with prior solid tumor (73.5% vs 66.4%; adjusted odds ratio, 1.65; 95% confidence interval, 1.03–2.65; p = .037), yet overall survival and relapse did not significantly differ. Cytogenetic risk was the dominant risk factor for survival. Conclusions Analysis by the authors suggests that patients with antecedent solid tumor and respective therapy can be transplanted successfully. Although selection bias is likely to be a factor, the results are encouraging for patients who come to transplantation after surviving a prior cancer." @default.
- W4307836700 created "2022-11-06" @default.
- W4307836700 creator A5028514579 @default.
- W4307836700 creator A5050374901 @default.
- W4307836700 creator A5062488059 @default.
- W4307836700 creator A5065574258 @default.
- W4307836700 date "2022-10-31" @default.
- W4307836700 modified "2023-09-30" @default.
- W4307836700 title "Transplantation for myeloid neoplasms with antecedent solid tumor" @default.
- W4307836700 cites W1969911820 @default.
- W4307836700 cites W2007532842 @default.
- W4307836700 cites W2049965335 @default.
- W4307836700 cites W2072301202 @default.
- W4307836700 cites W2078310345 @default.
- W4307836700 cites W2097540657 @default.
- W4307836700 cites W2128507218 @default.
- W4307836700 cites W2337969406 @default.
- W4307836700 cites W2340198921 @default.
- W4307836700 cites W2379365975 @default.
- W4307836700 cites W2936876518 @default.
- W4307836700 cites W307132063 @default.
- W4307836700 cites W3133628729 @default.
- W4307836700 cites W4221096040 @default.
- W4307836700 doi "https://doi.org/10.1002/cncr.34517" @default.
- W4307836700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36316954" @default.
- W4307836700 hasPublicationYear "2022" @default.
- W4307836700 type Work @default.
- W4307836700 citedByCount "1" @default.
- W4307836700 countsByYear W43078367002023 @default.
- W4307836700 crossrefType "journal-article" @default.
- W4307836700 hasAuthorship W4307836700A5028514579 @default.
- W4307836700 hasAuthorship W4307836700A5050374901 @default.
- W4307836700 hasAuthorship W4307836700A5062488059 @default.
- W4307836700 hasAuthorship W4307836700A5065574258 @default.
- W4307836700 hasConcept C120665830 @default.
- W4307836700 hasConcept C121332964 @default.
- W4307836700 hasConcept C121608353 @default.
- W4307836700 hasConcept C126322002 @default.
- W4307836700 hasConcept C141071460 @default.
- W4307836700 hasConcept C143998085 @default.
- W4307836700 hasConcept C156957248 @default.
- W4307836700 hasConcept C167135981 @default.
- W4307836700 hasConcept C2777408962 @default.
- W4307836700 hasConcept C2778461978 @default.
- W4307836700 hasConcept C2778729363 @default.
- W4307836700 hasConcept C2779282312 @default.
- W4307836700 hasConcept C2780007613 @default.
- W4307836700 hasConcept C2780817109 @default.
- W4307836700 hasConcept C2911091166 @default.
- W4307836700 hasConcept C61511704 @default.
- W4307836700 hasConcept C71924100 @default.
- W4307836700 hasConceptScore W4307836700C120665830 @default.
- W4307836700 hasConceptScore W4307836700C121332964 @default.
- W4307836700 hasConceptScore W4307836700C121608353 @default.
- W4307836700 hasConceptScore W4307836700C126322002 @default.
- W4307836700 hasConceptScore W4307836700C141071460 @default.
- W4307836700 hasConceptScore W4307836700C143998085 @default.
- W4307836700 hasConceptScore W4307836700C156957248 @default.
- W4307836700 hasConceptScore W4307836700C167135981 @default.
- W4307836700 hasConceptScore W4307836700C2777408962 @default.
- W4307836700 hasConceptScore W4307836700C2778461978 @default.
- W4307836700 hasConceptScore W4307836700C2778729363 @default.
- W4307836700 hasConceptScore W4307836700C2779282312 @default.
- W4307836700 hasConceptScore W4307836700C2780007613 @default.
- W4307836700 hasConceptScore W4307836700C2780817109 @default.
- W4307836700 hasConceptScore W4307836700C2911091166 @default.
- W4307836700 hasConceptScore W4307836700C61511704 @default.
- W4307836700 hasConceptScore W4307836700C71924100 @default.
- W4307836700 hasLocation W43078367001 @default.
- W4307836700 hasLocation W43078367002 @default.
- W4307836700 hasOpenAccess W4307836700 @default.
- W4307836700 hasPrimaryLocation W43078367001 @default.
- W4307836700 hasRelatedWork W1493011226 @default.
- W4307836700 hasRelatedWork W1984510961 @default.
- W4307836700 hasRelatedWork W2150998544 @default.
- W4307836700 hasRelatedWork W2791223330 @default.
- W4307836700 hasRelatedWork W2793298915 @default.
- W4307836700 hasRelatedWork W2804924284 @default.
- W4307836700 hasRelatedWork W2936131736 @default.
- W4307836700 hasRelatedWork W4226407928 @default.
- W4307836700 hasRelatedWork W4240210205 @default.
- W4307836700 hasRelatedWork W42711520 @default.
- W4307836700 isParatext "false" @default.
- W4307836700 isRetracted "false" @default.
- W4307836700 workType "article" @default.