Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307885319> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W4307885319 endingPage "1231" @default.
- W4307885319 startingPage "1231" @default.
- W4307885319 abstract "<ns4:p><ns4:bold>Background:</ns4:bold> Osteoarthritis (OA) is a degenerative joint disease characterized by deteriorating articular cartilage. Most patients may not get enough control of symptoms in spite of the availability of various treatment options. Because of the synergistic impact of flavonoids and ginkgolides, Ginkgo biloba (GB) has been shown to possess antioxidant and anti-inflammatory properties besides its generally safe profile. This study aims to assess the efficacy of the Ginkgo biloba extract (GBE) in patient with Knee OA<ns4:bold>. </ns4:bold></ns4:p><ns4:p> <ns4:bold>Methods:</ns4:bold> This is a randomized double blinded clinical trial conducted in a private orthopaedic clinic in Al-Najaf Government-Iraq. Patients were randomized into two groups; Group A administered the standard treatment (diclofenac capsule 100 milligram sustained released with paracetamol 1 gram twice daily) with GBE 120 milligram twice daily, while Group B administered the standard treatment with placebo (starch) capsule only. The Knee injury and Osteoarthritis Outcome Score (KOOS) was performed to assess the efficacy of the GBE in patient with Knee OA for eight weeks.</ns4:p><ns4:p> <ns4:bold>Results:</ns4:bold> 60 patients successfully completed the eight weeks follow up. Pain, symptoms, sport, activity of daily living (ADL) scores showed significant improvement in Group A from the first two weeks after treatment with GB in comparison with group B. however, scores of quality of life (QOL) were not significantly improved in two group comparison at each assessment week. Only 10 patients reported gastrointestinal adverse effects during the study which were all mild.</ns4:p><ns4:p> <ns4:bold>Conclusions:</ns4:bold> GB may provide additional beneficial health effects to patients with knee OA based on KOOS scores when add to the standard treatment regime.</ns4:p><ns4:p> <ns4:bold>Registration: </ns4:bold>ClincialTrials.gov (NCT05398874, <ns4:ext-link xmlns:ns5=http://www.w3.org/1999/xlink ext-link-type=uri ns5:href=https://clinicaltrials.gov/ct2/show/NCT05398874>https://clinicaltrials.gov/ct2/show/NCT05398874</ns4:ext-link>).</ns4:p>" @default.
- W4307885319 created "2022-11-06" @default.
- W4307885319 creator A5022392559 @default.
- W4307885319 creator A5042832003 @default.
- W4307885319 creator A5045017337 @default.
- W4307885319 creator A5061858104 @default.
- W4307885319 creator A5068646615 @default.
- W4307885319 date "2022-10-31" @default.
- W4307885319 modified "2023-10-14" @default.
- W4307885319 title "Evaluation of clinical efficacy of Ginkgo biloba extract in the treatment of knee osteoarthritis: a randomized clinical trial" @default.
- W4307885319 cites W1568081300 @default.
- W4307885319 cites W1716794597 @default.
- W4307885319 cites W1967057044 @default.
- W4307885319 cites W1981816788 @default.
- W4307885319 cites W1991120653 @default.
- W4307885319 cites W2002318957 @default.
- W4307885319 cites W2018777822 @default.
- W4307885319 cites W2022239812 @default.
- W4307885319 cites W2046667221 @default.
- W4307885319 cites W2062912295 @default.
- W4307885319 cites W2067384349 @default.
- W4307885319 cites W2083870327 @default.
- W4307885319 cites W2100631748 @default.
- W4307885319 cites W2123150676 @default.
- W4307885319 cites W2127129205 @default.
- W4307885319 cites W2162435037 @default.
- W4307885319 cites W2265780753 @default.
- W4307885319 cites W2335996711 @default.
- W4307885319 cites W2791401190 @default.
- W4307885319 cites W2939319192 @default.
- W4307885319 cites W3008805705 @default.
- W4307885319 cites W3107012386 @default.
- W4307885319 cites W4233138142 @default.
- W4307885319 cites W4252061509 @default.
- W4307885319 cites W4362730750 @default.
- W4307885319 doi "https://doi.org/10.12688/f1000research.126654.1" @default.
- W4307885319 hasPublicationYear "2022" @default.
- W4307885319 type Work @default.
- W4307885319 citedByCount "0" @default.
- W4307885319 crossrefType "journal-article" @default.
- W4307885319 hasAuthorship W4307885319A5022392559 @default.
- W4307885319 hasAuthorship W4307885319A5042832003 @default.
- W4307885319 hasAuthorship W4307885319A5045017337 @default.
- W4307885319 hasAuthorship W4307885319A5061858104 @default.
- W4307885319 hasAuthorship W4307885319A5068646615 @default.
- W4307885319 hasBestOaLocation W43078853191 @default.
- W4307885319 hasConcept C126322002 @default.
- W4307885319 hasConcept C142724271 @default.
- W4307885319 hasConcept C168563851 @default.
- W4307885319 hasConcept C197934379 @default.
- W4307885319 hasConcept C204787440 @default.
- W4307885319 hasConcept C27081682 @default.
- W4307885319 hasConcept C2776164576 @default.
- W4307885319 hasConcept C2778998842 @default.
- W4307885319 hasConcept C535046627 @default.
- W4307885319 hasConcept C71924100 @default.
- W4307885319 hasConcept C98274493 @default.
- W4307885319 hasConceptScore W4307885319C126322002 @default.
- W4307885319 hasConceptScore W4307885319C142724271 @default.
- W4307885319 hasConceptScore W4307885319C168563851 @default.
- W4307885319 hasConceptScore W4307885319C197934379 @default.
- W4307885319 hasConceptScore W4307885319C204787440 @default.
- W4307885319 hasConceptScore W4307885319C27081682 @default.
- W4307885319 hasConceptScore W4307885319C2776164576 @default.
- W4307885319 hasConceptScore W4307885319C2778998842 @default.
- W4307885319 hasConceptScore W4307885319C535046627 @default.
- W4307885319 hasConceptScore W4307885319C71924100 @default.
- W4307885319 hasConceptScore W4307885319C98274493 @default.
- W4307885319 hasLocation W43078853191 @default.
- W4307885319 hasOpenAccess W4307885319 @default.
- W4307885319 hasPrimaryLocation W43078853191 @default.
- W4307885319 hasRelatedWork W116688419 @default.
- W4307885319 hasRelatedWork W199441808 @default.
- W4307885319 hasRelatedWork W2064879719 @default.
- W4307885319 hasRelatedWork W2068655027 @default.
- W4307885319 hasRelatedWork W2085830368 @default.
- W4307885319 hasRelatedWork W2141413745 @default.
- W4307885319 hasRelatedWork W2162107430 @default.
- W4307885319 hasRelatedWork W4256514411 @default.
- W4307885319 hasRelatedWork W74714417 @default.
- W4307885319 hasRelatedWork W96715011 @default.
- W4307885319 hasVolume "11" @default.
- W4307885319 isParatext "false" @default.
- W4307885319 isRetracted "false" @default.
- W4307885319 workType "article" @default.