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- W4307947118 endingPage "13205" @default.
- W4307947118 startingPage "13205" @default.
- W4307947118 abstract "Leber’s Hereditary Optic Neuropathy (LHON) is the most common primary mitochondrial DNA disorder. It is characterized by bilateral severe central subacute vision loss due to specific loss of Retinal Ganglion Cells and their axons. Historically, treatment options have been quite limited, but ongoing clinical trials show promise, with significant advances being made in the testing of free radical scavengers and gene therapy. In this review, we summarize management strategies and rational of treatment based on current insights from molecular research. This includes preventative recommendations for unaffected genetic carriers, current medical and supportive treatments for those affected, and emerging evidence for future potential therapeutics." @default.
- W4307947118 created "2022-11-06" @default.
- W4307947118 creator A5022476386 @default.
- W4307947118 creator A5065390232 @default.
- W4307947118 date "2022-10-30" @default.
- W4307947118 modified "2023-10-16" @default.
- W4307947118 title "Solutions to a Radical Problem: Overview of Current and Future Treatment Strategies in Leber’s Hereditary Opic Neuropathy" @default.
- W4307947118 cites W1555547205 @default.
- W4307947118 cites W1627083208 @default.
- W4307947118 cites W1722845210 @default.
- W4307947118 cites W1724273473 @default.
- W4307947118 cites W1790985176 @default.
- W4307947118 cites W1966558304 @default.
- W4307947118 cites W1966986920 @default.
- W4307947118 cites W1971317397 @default.
- W4307947118 cites W1974620575 @default.
- W4307947118 cites W1980681204 @default.
- W4307947118 cites W2001507534 @default.
- W4307947118 cites W2002896548 @default.
- W4307947118 cites W2017347785 @default.
- W4307947118 cites W2036468060 @default.
- W4307947118 cites W2050871070 @default.
- W4307947118 cites W2053558205 @default.
- W4307947118 cites W2055053033 @default.
- W4307947118 cites W2058837644 @default.
- W4307947118 cites W2060256975 @default.
- W4307947118 cites W2062648177 @default.
- W4307947118 cites W2101656247 @default.
- W4307947118 cites W2106453714 @default.
- W4307947118 cites W2112785879 @default.
- W4307947118 cites W2121147116 @default.
- W4307947118 cites W2124154990 @default.
- W4307947118 cites W2125987139 @default.
- W4307947118 cites W2135118056 @default.
- W4307947118 cites W2138762261 @default.
- W4307947118 cites W2167665292 @default.
- W4307947118 cites W2179475984 @default.
- W4307947118 cites W2198724960 @default.
- W4307947118 cites W2207688209 @default.
- W4307947118 cites W2341581923 @default.
- W4307947118 cites W2392032054 @default.
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- W4307947118 cites W2596407832 @default.
- W4307947118 cites W2621975946 @default.
- W4307947118 cites W2734950774 @default.
- W4307947118 cites W2740313392 @default.
- W4307947118 cites W2763147200 @default.
- W4307947118 cites W2764051930 @default.
- W4307947118 cites W2782871901 @default.
- W4307947118 cites W2796157895 @default.
- W4307947118 cites W2804542054 @default.
- W4307947118 cites W2896277475 @default.
- W4307947118 cites W2909886378 @default.
- W4307947118 cites W2964704803 @default.
- W4307947118 cites W2990449924 @default.
- W4307947118 cites W2997274522 @default.
- W4307947118 cites W3002102878 @default.
- W4307947118 cites W3007936753 @default.
- W4307947118 cites W3011274305 @default.
- W4307947118 cites W3022810443 @default.
- W4307947118 cites W3023335238 @default.
- W4307947118 cites W3023709834 @default.
- W4307947118 cites W3024502913 @default.
- W4307947118 cites W3033705598 @default.
- W4307947118 cites W3087102910 @default.
- W4307947118 cites W3088837836 @default.
- W4307947118 cites W3089735243 @default.
- W4307947118 cites W3095446952 @default.
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- W4307947118 cites W3104240943 @default.
- W4307947118 cites W3112356895 @default.
- W4307947118 cites W3142506720 @default.
- W4307947118 cites W3158145908 @default.
- W4307947118 cites W3196147181 @default.
- W4307947118 cites W3216425243 @default.
- W4307947118 cites W3217333348 @default.
- W4307947118 cites W4224291888 @default.
- W4307947118 cites W4224880055 @default.
- W4307947118 cites W4226092171 @default.
- W4307947118 cites W4253932134 @default.
- W4307947118 cites W4280561832 @default.
- W4307947118 cites W4283832655 @default.
- W4307947118 cites W4285719527 @default.
- W4307947118 cites W4286251110 @default.
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- W4307947118 doi "https://doi.org/10.3390/ijms232113205" @default.
- W4307947118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36361994" @default.
- W4307947118 hasPublicationYear "2022" @default.
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