FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307970019> ?p ?o ?g. }

• W4307970019 endingPage "671" @default.
• W4307970019 startingPage "660" @default.
• W4307970019 abstract "BACKGROUND. Pulmonary function tests (PFTs) and perfusion scintigraphy have limited utility for evaluating postoperative changes in regional pulmonary function after lung cancer resection surgery. OBJECTIVE. The purpose of this study is to compare postoperative changes in lung volume and perfusion, as assessed by dual-energy CT (DECT), between patients undergoing surgical resection of lung cancer by lobectomy versus limited resection as well as to assess associations between such changes and the lobar location of the resected tumor. METHODS. This study entailed a retrospective post hoc analysis of a prospective study that enrolled patients awaiting lung cancer resection surgery between March 2019 and February 2020. Eighty-one patients (38 men and 43 women; mean age, 60.5 ± 8.9 [SD] years), 43 of whom underwent lobectomy and 38 of whom underwent limited resection, were included. Patients underwent thoracic DECT and PFT evaluation preoperatively and at 6 months postoperatively. Pulmonary lobes were segmented. Lobar lung volume and lung perfusion ratios (both relative to whole-lung values) were computed. Perfusion measures reflected DECT-derived iodine content. Patients completed 6-month postoperative quality-of-life (QOL) questionnaires. RESULTS. Patients undergoing lobectomy, compared with those undergoing limited resection, had greater increases in the lung volume ratio of the ipsilateral nonresected lobe(s) (mean, 42.3% ± 24.2% [SD] vs 22.9% ± 13.2%, p < .001) and the contralateral lung (mean, 14.6% ± 14.0% vs 6.4% ± 6.9%, p = .002) as well as greater increases in the lung perfusion ratio of the ipsilateral nonresected lobe(s) (mean, 39.9% ± 20.7% [SD] vs 22.8% ± 17.8%, p < .001) and the contralateral lung (mean, 20.9% ± 9.4% vs 4.3% ± 5.6%, p < .001). In patients with right lower lobe tumors, the largest postoperative increases in the lung volume ratio were in the right middle lobe in those undergoing lobectomy (mean, 44.1% ± 21.0%) and limited resection (mean, 24.6% ± 14.5%), whereas the largest postoperative increase in the lung perfusion ratio was in the left lower lobe in those undergoing lobectomy (mean, 53.9% ± 8.6%) and in the right middle lobe in those undergoing limited resection (mean, 32.5% ± 24.1%). Otherwise, the largest increases in lung volume and perfusion ratios occurred in the ipsilateral nonresected lobes (vs the contra-lateral lobes), regardless of the operative approach used and the lobar location. Changes in the lung volume and perfusion ratios in the ipsilateral lobe(s) and the contralateral lung showed weak correlations with certain QOL scores (e.g., for role functioning: ρ = 0.234-0.279 [volume] and -0.233 to -0.284 [perfusion]). CONCLUSION. DECT depicts patterns of lung volume and perfusion changes after lung cancer surgery, depending on the surgical approach (lobectomy vs limited resection) used and the lobar location of the tumor. CLINICAL IMPACT. DECT-derived metrics can help understand variable physiologic impacts of lung cancer resection surgeries." @default.
• W4307970019 created "2022-11-06" @default.
• W4307970019 creator A5005327028 @default.
• W4307970019 creator A5036277035 @default.
• W4307970019 creator A5044134935 @default.
• W4307970019 creator A5066750104 @default.
• W4307970019 creator A5079904600 @default.
• W4307970019 date "2023-05-01" @default.
• W4307970019 modified "2023-10-16" @default.
• W4307970019 title "Patterns of Postoperative Changes in Lung Volume and Perfusion Assessed by Dual-Energy CT: Comparison of Lobectomy and Limited Resection" @default.
• W4307970019 cites W130099911 @default.
• W4307970019 cites W1970521767 @default.
• W4307970019 cites W1982451654 @default.
• W4307970019 cites W2000166819 @default.
• W4307970019 cites W2001614807 @default.
• W4307970019 cites W2013677148 @default.
• W4307970019 cites W2019579518 @default.
• W4307970019 cites W2020164504 @default.
• W4307970019 cites W2027651309 @default.
• W4307970019 cites W2029969290 @default.
• W4307970019 cites W2046189285 @default.
• W4307970019 cites W2048393941 @default.
• W4307970019 cites W2061639182 @default.
• W4307970019 cites W2109567704 @default.
• W4307970019 cites W2125078269 @default.
• W4307970019 cites W2129836317 @default.
• W4307970019 cites W2167571044 @default.
• W4307970019 cites W2170650713 @default.
• W4307970019 cites W2171452405 @default.
• W4307970019 cites W2327037637 @default.
• W4307970019 cites W2355620008 @default.
• W4307970019 cites W2396151446 @default.
• W4307970019 cites W2408962589 @default.
• W4307970019 cites W2477736299 @default.
• W4307970019 cites W2486868414 @default.
• W4307970019 cites W2591641700 @default.
• W4307970019 cites W2616784627 @default.
• W4307970019 cites W2766245420 @default.
• W4307970019 cites W2793605650 @default.
• W4307970019 cites W2807634098 @default.
• W4307970019 cites W2883815546 @default.
• W4307970019 cites W2901122753 @default.
• W4307970019 cites W2935738022 @default.
• W4307970019 cites W4282941700 @default.
• W4307970019 doi "https://doi.org/10.2214/ajr.22.28450" @default.
• W4307970019 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36321980" @default.
• W4307970019 hasPublicationYear "2023" @default.
• W4307970019 type Work @default.
• W4307970019 citedByCount "1" @default.
• W4307970019 countsByYear W43079700192023 @default.
• W4307970019 crossrefType "journal-article" @default.
• W4307970019 hasAuthorship W4307970019A5005327028 @default.
• W4307970019 hasAuthorship W4307970019A5036277035 @default.
• W4307970019 hasAuthorship W4307970019A5044134935 @default.
• W4307970019 hasAuthorship W4307970019A5066750104 @default.
• W4307970019 hasAuthorship W4307970019A5079904600 @default.
• W4307970019 hasConcept C126322002 @default.
• W4307970019 hasConcept C126838900 @default.
• W4307970019 hasConcept C135691158 @default.
• W4307970019 hasConcept C141071460 @default.
• W4307970019 hasConcept C146957229 @default.
• W4307970019 hasConcept C27101514 @default.
• W4307970019 hasConcept C2776256026 @default.
• W4307970019 hasConcept C2777589429 @default.
• W4307970019 hasConcept C2777714996 @default.
• W4307970019 hasConcept C71924100 @default.
• W4307970019 hasConcept C75603125 @default.
• W4307970019 hasConceptScore W4307970019C126322002 @default.
• W4307970019 hasConceptScore W4307970019C126838900 @default.
• W4307970019 hasConceptScore W4307970019C135691158 @default.
• W4307970019 hasConceptScore W4307970019C141071460 @default.
• W4307970019 hasConceptScore W4307970019C146957229 @default.
• W4307970019 hasConceptScore W4307970019C27101514 @default.
• W4307970019 hasConceptScore W4307970019C2776256026 @default.
• W4307970019 hasConceptScore W4307970019C2777589429 @default.
• W4307970019 hasConceptScore W4307970019C2777714996 @default.
• W4307970019 hasConceptScore W4307970019C71924100 @default.
• W4307970019 hasConceptScore W4307970019C75603125 @default.
• W4307970019 hasIssue "5" @default.
• W4307970019 hasLocation W43079700191 @default.
• W4307970019 hasLocation W43079700192 @default.
• W4307970019 hasOpenAccess W4307970019 @default.
• W4307970019 hasPrimaryLocation W43079700191 @default.
• W4307970019 hasRelatedWork W1558200553 @default.
• W4307970019 hasRelatedWork W1966004774 @default.
• W4307970019 hasRelatedWork W2056218013 @default.
• W4307970019 hasRelatedWork W2143011408 @default.
• W4307970019 hasRelatedWork W2388581345 @default.
• W4307970019 hasRelatedWork W2410346915 @default.
• W4307970019 hasRelatedWork W2415013859 @default.
• W4307970019 hasRelatedWork W2440893755 @default.
• W4307970019 hasRelatedWork W2463497286 @default.
• W4307970019 hasRelatedWork W4210633027 @default.
• W4307970019 hasVolume "220" @default.
• W4307970019 isParatext "false" @default.
• W4307970019 isRetracted "false" @default.
• W4307970019 workType "article" @default.