Matches in SemOpenAlex for { <https://semopenalex.org/work/W4307995058> ?p ?o ?g. }
- W4307995058 endingPage "13390" @default.
- W4307995058 startingPage "13390" @default.
- W4307995058 abstract "Accumulation of α-synuclein (α-syn) is the pathological hallmark of α-synucleinopathy. Rapid eye movement (REM) sleep behavior disorder (RBD) is a pivotal manifestation of α-synucleinopathy including Parkinson’s disease (PD). RBD is clinically confirmed by REM sleep without atonia (RWA) in polysomnography. To accurately characterize RWA preceding RBD and their underlying α-syn pathology, we inoculated α-syn preformed fibrils (PFFs) into the striatum of A53T human α-syn BAC transgenic (A53T BAC-SNCA Tg) mice which exhibit RBD-like phenotypes with RWA. RWA phenotypes were aggravated by PFFs-inoculation in A53T BAC-SNCA Tg mice at 1 month after inoculation, in which prominent α-syn pathology in the pedunculopontine nucleus (PPN) was observed. The intensity of RWA phenotype could be dependent on the severity of the underlying α-syn pathology." @default.
- W4307995058 created "2022-11-07" @default.
- W4307995058 creator A5028416366 @default.
- W4307995058 creator A5034964130 @default.
- W4307995058 creator A5036976658 @default.
- W4307995058 creator A5039847431 @default.
- W4307995058 creator A5040873235 @default.
- W4307995058 creator A5048554479 @default.
- W4307995058 creator A5061304175 @default.
- W4307995058 creator A5078340877 @default.
- W4307995058 creator A5083789953 @default.
- W4307995058 creator A5090721367 @default.
- W4307995058 creator A5036747792 @default.
- W4307995058 date "2022-11-02" @default.
- W4307995058 modified "2023-10-13" @default.
- W4307995058 title "Striatal-Inoculation of α-Synuclein Preformed Fibrils Aggravated the Phenotypes of REM Sleep without Atonia in A53T BAC-SNCA Transgenic Mice" @default.
- W4307995058 cites W1560873021 @default.
- W4307995058 cites W1657459197 @default.
- W4307995058 cites W1995170630 @default.
- W4307995058 cites W2013331421 @default.
- W4307995058 cites W2073912959 @default.
- W4307995058 cites W2115859705 @default.
- W4307995058 cites W2131222480 @default.
- W4307995058 cites W2136161753 @default.
- W4307995058 cites W2170262356 @default.
- W4307995058 cites W2539957110 @default.
- W4307995058 cites W2562166359 @default.
- W4307995058 cites W2750093297 @default.
- W4307995058 cites W2805466047 @default.
- W4307995058 cites W2921249256 @default.
- W4307995058 cites W2995538686 @default.
- W4307995058 cites W3000291726 @default.
- W4307995058 cites W3102231089 @default.
- W4307995058 cites W3103593628 @default.
- W4307995058 cites W3138307738 @default.
- W4307995058 cites W3171613899 @default.
- W4307995058 cites W3185228246 @default.
- W4307995058 cites W4226077434 @default.
- W4307995058 cites W842540573 @default.
- W4307995058 doi "https://doi.org/10.3390/ijms232113390" @default.
- W4307995058 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36362177" @default.
- W4307995058 hasPublicationYear "2022" @default.
- W4307995058 type Work @default.
- W4307995058 citedByCount "1" @default.
- W4307995058 countsByYear W43079950582023 @default.
- W4307995058 crossrefType "journal-article" @default.
- W4307995058 hasAuthorship W4307995058A5028416366 @default.
- W4307995058 hasAuthorship W4307995058A5034964130 @default.
- W4307995058 hasAuthorship W4307995058A5036747792 @default.
- W4307995058 hasAuthorship W4307995058A5036976658 @default.
- W4307995058 hasAuthorship W4307995058A5039847431 @default.
- W4307995058 hasAuthorship W4307995058A5040873235 @default.
- W4307995058 hasAuthorship W4307995058A5048554479 @default.
- W4307995058 hasAuthorship W4307995058A5061304175 @default.
- W4307995058 hasAuthorship W4307995058A5078340877 @default.
- W4307995058 hasAuthorship W4307995058A5083789953 @default.
- W4307995058 hasAuthorship W4307995058A5090721367 @default.
- W4307995058 hasBestOaLocation W43079950581 @default.
- W4307995058 hasConcept C102230213 @default.
- W4307995058 hasConcept C104317684 @default.
- W4307995058 hasConcept C127716648 @default.
- W4307995058 hasConcept C141035611 @default.
- W4307995058 hasConcept C142724271 @default.
- W4307995058 hasConcept C153050134 @default.
- W4307995058 hasConcept C169760540 @default.
- W4307995058 hasConcept C2777440831 @default.
- W4307995058 hasConcept C2777916540 @default.
- W4307995058 hasConcept C2778205975 @default.
- W4307995058 hasConcept C2779134260 @default.
- W4307995058 hasConcept C2779213384 @default.
- W4307995058 hasConcept C2779734285 @default.
- W4307995058 hasConcept C2781449126 @default.
- W4307995058 hasConcept C522805319 @default.
- W4307995058 hasConcept C54355233 @default.
- W4307995058 hasConcept C71924100 @default.
- W4307995058 hasConcept C86803240 @default.
- W4307995058 hasConceptScore W4307995058C102230213 @default.
- W4307995058 hasConceptScore W4307995058C104317684 @default.
- W4307995058 hasConceptScore W4307995058C127716648 @default.
- W4307995058 hasConceptScore W4307995058C141035611 @default.
- W4307995058 hasConceptScore W4307995058C142724271 @default.
- W4307995058 hasConceptScore W4307995058C153050134 @default.
- W4307995058 hasConceptScore W4307995058C169760540 @default.
- W4307995058 hasConceptScore W4307995058C2777440831 @default.
- W4307995058 hasConceptScore W4307995058C2777916540 @default.
- W4307995058 hasConceptScore W4307995058C2778205975 @default.
- W4307995058 hasConceptScore W4307995058C2779134260 @default.
- W4307995058 hasConceptScore W4307995058C2779213384 @default.
- W4307995058 hasConceptScore W4307995058C2779734285 @default.
- W4307995058 hasConceptScore W4307995058C2781449126 @default.
- W4307995058 hasConceptScore W4307995058C522805319 @default.
- W4307995058 hasConceptScore W4307995058C54355233 @default.
- W4307995058 hasConceptScore W4307995058C71924100 @default.
- W4307995058 hasConceptScore W4307995058C86803240 @default.
- W4307995058 hasFunder F4320311405 @default.
- W4307995058 hasFunder F4320334789 @default.
- W4307995058 hasIssue "21" @default.
- W4307995058 hasLocation W43079950581 @default.