FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308016222> ?p ?o ?g. }

• W4308016222 endingPage "14" @default.
• W4308016222 startingPage "1" @default.
• W4308016222 abstract "Advanced glycation end products (AGEs) are formed via a nonenzymatic glycosylation reaction called glycation. The formation and accumulation of AGEs increases in skin with age, contributing to the appearance of facial wrinkles and loss of skin elasticity. Therefore, inhibition of AGEs may delay skin aging. The microalgae Parachlorella beijerinckii has been used as a health food supplement for many years and contains carotenoids and vitamins that have antioxidant and anti-inflammatory effects. The aim of this study was to investigate whether Chlorella extract also has antiglycation activity. Antiglycation activity was measured using fluorescent AGEs, Nε-(carboxymethyl) lysine (CML), and Nε-(carboxymethyl) arginine (CMA) from glycated bovine serum albumin and type I collagen in vitro. A gel with a dermis-like structure consisting of collagen and a live fibroblast cell line was glycated with glyoxal. The content of fluorescent AGE, CML, and CMA, and the gel contraction activity were measured. In addition, to investigate the level of inflammation induced by the glycation of the collagen gel, the expression level of the receptor for AGEs and interleukin-8 were examined. Fat-solubleChlorella extract suppressed the formation of fluorescent AGEs, CML, and CMA in both models. These results indicated that Chlorella extract directly inhibited AGE formation. The collagen gel contracted over time during culturing, whereas contraction was inhibited in the glyoxal-treated collagen gel. Chlorella extract remarkably attenuated the glyoxal-induced gel contraction. Moreover, Chlorella extract substantially decreased the fluorescent AGEs, CML, and CMA in the collagen gels with glyoxal. Glyoxal exposure increased the expression levels of interleukin-8 and receptor for AGE proteins in collagen gels, while Chlorella extract inhibited this increase. This study showed that fat-solubleChlorella extract has a direct inhibitory effect on AGEs and decreases receptor expression for AGE-mediated inflammation by reducing AGEs. Chlorella may delay skin aging by inhibiting the formation and accumulation of AGEs." @default.
• W4308016222 created "2022-11-07" @default.
• W4308016222 creator A5016798021 @default.
• W4308016222 creator A5045587907 @default.
• W4308016222 creator A5046445805 @default.
• W4308016222 date "2022-11-01" @default.
• W4308016222 modified "2023-10-16" @default.
• W4308016222 title "Inhibitory Effects of Parachlorella Beijerinckii Extracts on the Formation of Advanced Glycation End Products and Glycative Stress-Induced Inflammation in an In Vitro Skin Dermis-Like Model" @default.
• W4308016222 cites W1521386149 @default.
• W4308016222 cites W1964908547 @default.
• W4308016222 cites W1968862009 @default.
• W4308016222 cites W1976477824 @default.
• W4308016222 cites W1978793468 @default.
• W4308016222 cites W1990675333 @default.
• W4308016222 cites W1996895672 @default.
• W4308016222 cites W1997200123 @default.
• W4308016222 cites W1997512217 @default.
• W4308016222 cites W2024293486 @default.
• W4308016222 cites W2024841060 @default.
• W4308016222 cites W2035755932 @default.
• W4308016222 cites W2036035870 @default.
• W4308016222 cites W2043999306 @default.
• W4308016222 cites W2049925019 @default.
• W4308016222 cites W2052681712 @default.
• W4308016222 cites W205336007 @default.
• W4308016222 cites W2054221638 @default.
• W4308016222 cites W2055254758 @default.
• W4308016222 cites W2055703043 @default.
• W4308016222 cites W2059341662 @default.
• W4308016222 cites W2060196422 @default.
• W4308016222 cites W2066796217 @default.
• W4308016222 cites W2080579410 @default.
• W4308016222 cites W2080634920 @default.
• W4308016222 cites W2106218976 @default.
• W4308016222 cites W2108918917 @default.
• W4308016222 cites W2109334664 @default.
• W4308016222 cites W2118953500 @default.
• W4308016222 cites W2125764628 @default.
• W4308016222 cites W2153846037 @default.
• W4308016222 cites W2281636533 @default.
• W4308016222 cites W2302716071 @default.
• W4308016222 cites W2307456086 @default.
• W4308016222 cites W2470383613 @default.
• W4308016222 cites W2552261413 @default.
• W4308016222 cites W2770031651 @default.
• W4308016222 cites W2784297804 @default.
• W4308016222 cites W2804099465 @default.
• W4308016222 cites W2805227313 @default.
• W4308016222 cites W2809121498 @default.
• W4308016222 cites W2937455106 @default.
• W4308016222 cites W2972987204 @default.
• W4308016222 cites W2980864577 @default.
• W4308016222 cites W2982209712 @default.
• W4308016222 cites W3092170190 @default.
• W4308016222 cites W3162902294 @default.
• W4308016222 cites W3205224905 @default.
• W4308016222 doi "https://doi.org/10.1155/2022/8789903" @default.
• W4308016222 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36387367" @default.
• W4308016222 hasPublicationYear "2022" @default.
• W4308016222 type Work @default.
• W4308016222 citedByCount "1" @default.
• W4308016222 countsByYear W43080162222023 @default.
• W4308016222 crossrefType "journal-article" @default.
• W4308016222 hasAuthorship W4308016222A5016798021 @default.
• W4308016222 hasAuthorship W4308016222A5045587907 @default.
• W4308016222 hasAuthorship W4308016222A5046445805 @default.
• W4308016222 hasBestOaLocation W43080162221 @default.
• W4308016222 hasConcept C105702510 @default.
• W4308016222 hasConcept C134018914 @default.
• W4308016222 hasConcept C147990577 @default.
• W4308016222 hasConcept C153911025 @default.
• W4308016222 hasConcept C170493617 @default.
• W4308016222 hasConcept C178790620 @default.
• W4308016222 hasConcept C181199279 @default.
• W4308016222 hasConcept C185592680 @default.
• W4308016222 hasConcept C202751555 @default.
• W4308016222 hasConcept C2776016237 @default.
• W4308016222 hasConcept C2776997535 @default.
• W4308016222 hasConcept C2777180221 @default.
• W4308016222 hasConcept C2777538456 @default.
• W4308016222 hasConcept C2777603720 @default.
• W4308016222 hasConcept C2777624698 @default.
• W4308016222 hasConcept C2778005187 @default.
• W4308016222 hasConcept C2778592357 @default.
• W4308016222 hasConcept C2780381497 @default.
• W4308016222 hasConcept C35378473 @default.
• W4308016222 hasConcept C515207424 @default.
• W4308016222 hasConcept C55493867 @default.
• W4308016222 hasConcept C555293320 @default.
• W4308016222 hasConcept C86803240 @default.
• W4308016222 hasConceptScore W4308016222C105702510 @default.
• W4308016222 hasConceptScore W4308016222C134018914 @default.
• W4308016222 hasConceptScore W4308016222C147990577 @default.
• W4308016222 hasConceptScore W4308016222C153911025 @default.
• W4308016222 hasConceptScore W4308016222C170493617 @default.
• W4308016222 hasConceptScore W4308016222C178790620 @default.
• W4308016222 hasConceptScore W4308016222C181199279 @default.
• W4308016222 hasConceptScore W4308016222C185592680 @default.

• next