FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308016895> ?p ?o ?g. }

• W4308016895 endingPage "e064517" @default.
• W4308016895 startingPage "e064517" @default.
• W4308016895 abstract "Introduction Long-term cognitive impairment is one of the most common complications of critical illness among survivors who receive mechanical ventilation. Recommended oxygen targets during mechanical ventilation vary among international guidelines. Different oxygen targets during mechanical ventilation have the potential to alter long-term cognitive function due to cerebral hypoxemia or hyperoxemia. Whether higher, intermediate or lower SpO 2 targets are associated with better cognitive function at 12-month follow-up is unknown. Methods and analysis The P ragmatic I nvestigation of optima L O xygen T argets (PILOT) trial is an ongoing pragmatic, cluster-randomised, cluster-crossover trial comparing the effect of a higher SpO 2 target (target 98%, goal range 96%–100%), an intermediate SpO 2 target (target 94%, goal range 92%–96%) and a lower SpO 2 target (target 90%, goal range 88%–92%) on clinical outcomes in mechanically ventilated patients admitted to the medical intensive care unit at a single centre in the USA. For this ancillary study of long-term C ognitive O utcomes (CO-PILOT), survivors of critical illness who are in the PILOT trial and who do not meet exclusion criteria for CO-PILOT are approached for consent. The anticipated number of patients for whom assessment of long-term cognition will be performed in CO-PILOT is 612 patients over 36 months of enrolment. Cognitive, functional and quality of life assessments are assessed via telephone interview at approximately 12 months after enrolment in PILOT. The primary outcome of CO-PILOT is the telephone version of the Montreal Cognitive Assessment. A subset of patients will also complete a comprehensive neuropsychological telephone battery to better characterise the cognitive domains affected. Ethics and dissemination The CO-PILOT ancillary study was approved by the Vanderbilt Institutional Review Board. The results will be submitted for publication in a peer-reviewed journal and presented at one or more scientific conferences." @default.
• W4308016895 created "2022-11-07" @default.
• W4308016895 creator A5001983594 @default.
• W4308016895 creator A5003593760 @default.
• W4308016895 creator A5006953289 @default.
• W4308016895 creator A5011550951 @default.
• W4308016895 creator A5012278873 @default.
• W4308016895 creator A5016346905 @default.
• W4308016895 creator A5017621103 @default.
• W4308016895 creator A5022163916 @default.
• W4308016895 creator A5033034338 @default.
• W4308016895 creator A5034795352 @default.
• W4308016895 creator A5038114338 @default.
• W4308016895 creator A5046059470 @default.
• W4308016895 creator A5049402910 @default.
• W4308016895 creator A5052393113 @default.
• W4308016895 creator A5056180482 @default.
• W4308016895 creator A5073290483 @default.
• W4308016895 creator A5077126004 @default.
• W4308016895 creator A5079881042 @default.
• W4308016895 date "2022-11-01" @default.
• W4308016895 modified "2023-10-16" @default.
• W4308016895 title "Cognitive Outcomes in the Pragmatic Investigation of optimaL Oxygen Targets (CO-PILOT) trial: protocol and statistical analysis plan" @default.
• W4308016895 cites W1928918188 @default.
• W4308016895 cites W1974798003 @default.
• W4308016895 cites W1976147378 @default.
• W4308016895 cites W1977733462 @default.
• W4308016895 cites W1988429877 @default.
• W4308016895 cites W2006318999 @default.
• W4308016895 cites W2009691381 @default.
• W4308016895 cites W2019158475 @default.
• W4308016895 cites W2023658755 @default.
• W4308016895 cites W2065974896 @default.
• W4308016895 cites W2074086852 @default.
• W4308016895 cites W2077201173 @default.
• W4308016895 cites W2085870059 @default.
• W4308016895 cites W2087046046 @default.
• W4308016895 cites W2088893559 @default.
• W4308016895 cites W2093274439 @default.
• W4308016895 cites W2096782143 @default.
• W4308016895 cites W2097395684 @default.
• W4308016895 cites W2100937752 @default.
• W4308016895 cites W2101048381 @default.
• W4308016895 cites W2101436344 @default.
• W4308016895 cites W2104796318 @default.
• W4308016895 cites W2104878804 @default.
• W4308016895 cites W2108485082 @default.
• W4308016895 cites W2110026768 @default.
• W4308016895 cites W2117542631 @default.
• W4308016895 cites W2117839048 @default.
• W4308016895 cites W2121506020 @default.
• W4308016895 cites W2123098876 @default.
• W4308016895 cites W2124314037 @default.
• W4308016895 cites W2127841934 @default.
• W4308016895 cites W2134190092 @default.
• W4308016895 cites W2138141660 @default.
• W4308016895 cites W2146635389 @default.
• W4308016895 cites W2153836018 @default.
• W4308016895 cites W2160722967 @default.
• W4308016895 cites W2163104804 @default.
• W4308016895 cites W2165758561 @default.
• W4308016895 cites W2364333349 @default.
• W4308016895 cites W2480680997 @default.
• W4308016895 cites W2528556615 @default.
• W4308016895 cites W2587881246 @default.
• W4308016895 cites W2604193015 @default.
• W4308016895 cites W2615920393 @default.
• W4308016895 cites W2617732284 @default.
• W4308016895 cites W2765657382 @default.
• W4308016895 cites W2786198454 @default.
• W4308016895 cites W2896197442 @default.
• W4308016895 cites W2979851589 @default.
• W4308016895 cites W2980403271 @default.
• W4308016895 cites W3010551088 @default.
• W4308016895 cites W3011047309 @default.
• W4308016895 cites W3047379779 @default.
• W4308016895 cites W3082117691 @default.
• W4308016895 cites W3121451006 @default.
• W4308016895 cites W3127898334 @default.
• W4308016895 cites W3128362325 @default.
• W4308016895 cites W3141617381 @default.
• W4308016895 cites W3144214964 @default.
• W4308016895 cites W3165060638 @default.
• W4308016895 cites W3172018166 @default.
• W4308016895 cites W3209293982 @default.
• W4308016895 cites W4224237705 @default.
• W4308016895 cites W4244453275 @default.
• W4308016895 cites W4248783750 @default.
• W4308016895 doi "https://doi.org/10.1136/bmjopen-2022-064517" @default.
• W4308016895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36319061" @default.
• W4308016895 hasPublicationYear "2022" @default.
• W4308016895 type Work @default.
• W4308016895 citedByCount "0" @default.
• W4308016895 crossrefType "journal-article" @default.
• W4308016895 hasAuthorship W4308016895A5001983594 @default.
• W4308016895 hasAuthorship W4308016895A5003593760 @default.
• W4308016895 hasAuthorship W4308016895A5006953289 @default.
• W4308016895 hasAuthorship W4308016895A5011550951 @default.

• next