FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308019803> ?p ?o ?g. }

• W4308019803 abstract "The aim of this prospective study was to investigate the prognostic value of metabolic tumor volume (MTV) and apparent diffusion coefficient (ADC) from baseline FDG PET/MRI compared to established clinical risk factors in terms of progression free survival (PFS) at 2 years in a cohort of diffuse large B-cell Lymphoma (DLBCL) and high-grade-B-cell lymphoma (HGBCL).Thirty-three patients and their baseline PET/MRI examinations were included. Images were read by two pairs of nuclear medicine physicians and radiologists for defining lymphoma lesions. MTV was computed on PET, and up to six lymphoma target lesions with restricted diffusion was defined for each PET/MRI examination. Minimum ADC (ADCmin) and the corresponding mean ADC (ADCmean) from the target lesion with the lowest ADCmin were included in the analyses. For the combined PET/MRI parameters, the ratio between MTV and the target lesion with the lowest ADCmin (MTV/ADCmin) and the corresponding ADCmean (MTV/ADCmean) was calculated for each patient. Clinical, histological, and PET/MRI parameters were compared between the treatment failure and treatment response group, while survival analyses for each variable was performed by using univariate Cox regression. In case of significant variables in the Cox regression analyses, Kaplan-Meier survival analyses with log-rank test was used to study the effect of the variables on PFS.ECOC PS scale ≥2 (p = 0.05) and ADCmean (p = 0.05) were significantly different between the treatment failure group (n = 6) and those with treatment response (n = 27). Survival analyses showed that ADCmean was associated with PFS (p = 0.02, [HR 2.3 for 1 SD increase]), while combining MTV and ADC did not predict outcome. In addition, ECOG PS ≥2 (p = 0.01, [HR 13.3]) and histology of HGBCL (p = 0.02 [HR 7.6]) was significantly associated with PFS.ADCmean derived from baseline MRI could be a prognostic imaging biomarker for DLBCL and HGBCL. Baseline staging with PET/MRI could therefore give supplementary prognostic information compared to today's standard PET/CT." @default.
• W4308019803 created "2022-11-07" @default.
• W4308019803 creator A5029713359 @default.
• W4308019803 creator A5039994984 @default.
• W4308019803 creator A5051450119 @default.
• W4308019803 creator A5059078685 @default.
• W4308019803 creator A5059544571 @default.
• W4308019803 creator A5065214625 @default.
• W4308019803 creator A5069737334 @default.
• W4308019803 creator A5082972097 @default.
• W4308019803 creator A5091832842 @default.
• W4308019803 date "2022-11-01" @default.
• W4308019803 modified "2023-09-26" @default.
• W4308019803 title "Prognostic value of combined MTV and ADC derived from baseline FDG PET/MRI in aggressive non-Hodgkins lymphoma" @default.
• W4308019803 cites W1979530620 @default.
• W4308019803 cites W1988520617 @default.
• W4308019803 cites W1997276706 @default.
• W4308019803 cites W2027277668 @default.
• W4308019803 cites W2063563316 @default.
• W4308019803 cites W2102602525 @default.
• W4308019803 cites W2106705123 @default.
• W4308019803 cites W2119147717 @default.
• W4308019803 cites W2162506220 @default.
• W4308019803 cites W2167556523 @default.
• W4308019803 cites W2168194866 @default.
• W4308019803 cites W2265408461 @default.
• W4308019803 cites W2275941472 @default.
• W4308019803 cites W2410044728 @default.
• W4308019803 cites W2507439586 @default.
• W4308019803 cites W2598700764 @default.
• W4308019803 cites W2613771991 @default.
• W4308019803 cites W2783946358 @default.
• W4308019803 cites W2807236643 @default.
• W4308019803 cites W2915292973 @default.
• W4308019803 cites W3002263815 @default.
• W4308019803 cites W3024375698 @default.
• W4308019803 cites W3043558719 @default.
• W4308019803 cites W3132105816 @default.
• W4308019803 cites W3158313069 @default.
• W4308019803 cites W3193510908 @default.
• W4308019803 cites W4212890013 @default.
• W4308019803 doi "https://doi.org/10.1186/s12885-022-10194-2" @default.
• W4308019803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36319985" @default.
• W4308019803 hasPublicationYear "2022" @default.
• W4308019803 type Work @default.
• W4308019803 citedByCount "0" @default.
• W4308019803 crossrefType "journal-article" @default.
• W4308019803 hasAuthorship W4308019803A5029713359 @default.
• W4308019803 hasAuthorship W4308019803A5039994984 @default.
• W4308019803 hasAuthorship W4308019803A5051450119 @default.
• W4308019803 hasAuthorship W4308019803A5059078685 @default.
• W4308019803 hasAuthorship W4308019803A5059544571 @default.
• W4308019803 hasAuthorship W4308019803A5065214625 @default.
• W4308019803 hasAuthorship W4308019803A5069737334 @default.
• W4308019803 hasAuthorship W4308019803A5082972097 @default.
• W4308019803 hasAuthorship W4308019803A5091832842 @default.
• W4308019803 hasBestOaLocation W43080198031 @default.
• W4308019803 hasConcept C126322002 @default.
• W4308019803 hasConcept C126838900 @default.
• W4308019803 hasConcept C142724271 @default.
• W4308019803 hasConcept C143409427 @default.
• W4308019803 hasConcept C144301174 @default.
• W4308019803 hasConcept C199374082 @default.
• W4308019803 hasConcept C2775842073 @default.
• W4308019803 hasConcept C2778559949 @default.
• W4308019803 hasConcept C2779338263 @default.
• W4308019803 hasConcept C2989005 @default.
• W4308019803 hasConcept C38180746 @default.
• W4308019803 hasConcept C50382708 @default.
• W4308019803 hasConcept C70816921 @default.
• W4308019803 hasConcept C71924100 @default.
• W4308019803 hasConceptScore W4308019803C126322002 @default.
• W4308019803 hasConceptScore W4308019803C126838900 @default.
• W4308019803 hasConceptScore W4308019803C142724271 @default.
• W4308019803 hasConceptScore W4308019803C143409427 @default.
• W4308019803 hasConceptScore W4308019803C144301174 @default.
• W4308019803 hasConceptScore W4308019803C199374082 @default.
• W4308019803 hasConceptScore W4308019803C2775842073 @default.
• W4308019803 hasConceptScore W4308019803C2778559949 @default.
• W4308019803 hasConceptScore W4308019803C2779338263 @default.
• W4308019803 hasConceptScore W4308019803C2989005 @default.
• W4308019803 hasConceptScore W4308019803C38180746 @default.
• W4308019803 hasConceptScore W4308019803C50382708 @default.
• W4308019803 hasConceptScore W4308019803C70816921 @default.
• W4308019803 hasConceptScore W4308019803C71924100 @default.
• W4308019803 hasIssue "1" @default.
• W4308019803 hasLocation W43080198031 @default.
• W4308019803 hasLocation W43080198032 @default.
• W4308019803 hasLocation W43080198033 @default.
• W4308019803 hasLocation W43080198034 @default.
• W4308019803 hasLocation W43080198035 @default.
• W4308019803 hasOpenAccess W4308019803 @default.
• W4308019803 hasPrimaryLocation W43080198031 @default.
• W4308019803 hasRelatedWork W1575274804 @default.
• W4308019803 hasRelatedWork W1998534699 @default.
• W4308019803 hasRelatedWork W2012019590 @default.
• W4308019803 hasRelatedWork W2111347914 @default.
• W4308019803 hasRelatedWork W2144065509 @default.
• W4308019803 hasRelatedWork W2186028194 @default.
• W4308019803 hasRelatedWork W2396824403 @default.

• next