FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308077984> ?p ?o ?g. }

• W4308077984 endingPage "e0274916" @default.
• W4308077984 startingPage "e0274916" @default.
• W4308077984 abstract "The present study intends to formulate, characterize and appraise the phospholipid-based nanovesicular system for enhanced delivery of Hesperetin (HT). The quality by design (QbD) approach was employed to prepare Hesperetin naturosomes (HTN) using the solvent evaporation technique and assessed for physicochemical and pharmacological attributes. The FTIR, DSC, and PXRD studies confirmed the successful formation of a vesicular drug-phospholipid complex, while photomicroscopy, SEM, and TEM analysis revealed the morphology of HTN. The functional attributes substantially enhanced the HT's aqueous solubility, drug release, and membrane permeation. The aqueous solubility of HTN was ~10-fold more than that of pure HT. Likewise, the in-vitro dissolution data of HTN showed better competence in releasing the HT (>93%) than the pure HT (~64%) or the physical mixture (~74%). Furthermore, HTN significantly altered HT permeation (>53%) when compared to pure HT (23%) or the physical mixture (28%). The current study showed that naturosomes are a promising way to improve the solubility in water, bioavailability, and therapeutic effectiveness of drugs." @default.
• W4308077984 created "2022-11-08" @default.
• W4308077984 creator A5022131677 @default.
• W4308077984 creator A5023995636 @default.
• W4308077984 creator A5030484615 @default.
• W4308077984 creator A5032580557 @default.
• W4308077984 creator A5035391728 @default.
• W4308077984 creator A5046677466 @default.
• W4308077984 creator A5061787910 @default.
• W4308077984 creator A5081496795 @default.
• W4308077984 creator A5091051400 @default.
• W4308077984 creator A5091741000 @default.
• W4308077984 date "2022-11-03" @default.
• W4308077984 modified "2023-10-07" @default.
• W4308077984 title "Preparation, characterization, and evaluation (in-vitro, ex-vivo, and in-vivo) of naturosomal nanocarriers for enhanced delivery and therapeutic efficacy of hesperetin" @default.
• W4308077984 cites W2001835005 @default.
• W4308077984 cites W2006350459 @default.
• W4308077984 cites W2020143653 @default.
• W4308077984 cites W2021484540 @default.
• W4308077984 cites W2043048607 @default.
• W4308077984 cites W2044681516 @default.
• W4308077984 cites W2053446727 @default.
• W4308077984 cites W2091132460 @default.
• W4308077984 cites W2120241355 @default.
• W4308077984 cites W2134098311 @default.
• W4308077984 cites W2177957280 @default.
• W4308077984 cites W2419604940 @default.
• W4308077984 cites W2767234884 @default.
• W4308077984 cites W2884383626 @default.
• W4308077984 cites W2887575633 @default.
• W4308077984 cites W3083735200 @default.
• W4308077984 cites W3109000026 @default.
• W4308077984 cites W3130042235 @default.
• W4308077984 cites W4206517796 @default.
• W4308077984 cites W4221058693 @default.
• W4308077984 cites W4225322529 @default.
• W4308077984 cites W4281289199 @default.
• W4308077984 doi "https://doi.org/10.1371/journal.pone.0274916" @default.
• W4308077984 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36327264" @default.
• W4308077984 hasPublicationYear "2022" @default.
• W4308077984 type Work @default.
• W4308077984 citedByCount "4" @default.
• W4308077984 countsByYear W43080779842023 @default.
• W4308077984 crossrefType "journal-article" @default.
• W4308077984 hasAuthorship W4308077984A5022131677 @default.
• W4308077984 hasAuthorship W4308077984A5023995636 @default.
• W4308077984 hasAuthorship W4308077984A5030484615 @default.
• W4308077984 hasAuthorship W4308077984A5032580557 @default.
• W4308077984 hasAuthorship W4308077984A5035391728 @default.
• W4308077984 hasAuthorship W4308077984A5046677466 @default.
• W4308077984 hasAuthorship W4308077984A5061787910 @default.
• W4308077984 hasAuthorship W4308077984A5081496795 @default.
• W4308077984 hasAuthorship W4308077984A5091051400 @default.
• W4308077984 hasAuthorship W4308077984A5091741000 @default.
• W4308077984 hasBestOaLocation W43080779841 @default.
• W4308077984 hasConcept C130316041 @default.
• W4308077984 hasConcept C150903083 @default.
• W4308077984 hasConcept C155574463 @default.
• W4308077984 hasConcept C178790620 @default.
• W4308077984 hasConcept C181389837 @default.
• W4308077984 hasConcept C18150654 @default.
• W4308077984 hasConcept C185592680 @default.
• W4308077984 hasConcept C207001950 @default.
• W4308077984 hasConcept C2777252647 @default.
• W4308077984 hasConcept C2778004101 @default.
• W4308077984 hasConcept C2779054382 @default.
• W4308077984 hasConcept C2779820397 @default.
• W4308077984 hasConcept C41625074 @default.
• W4308077984 hasConcept C43617362 @default.
• W4308077984 hasConcept C50670333 @default.
• W4308077984 hasConcept C55493867 @default.
• W4308077984 hasConcept C71924100 @default.
• W4308077984 hasConcept C72918618 @default.
• W4308077984 hasConcept C86803240 @default.
• W4308077984 hasConcept C98274493 @default.
• W4308077984 hasConceptScore W4308077984C130316041 @default.
• W4308077984 hasConceptScore W4308077984C150903083 @default.
• W4308077984 hasConceptScore W4308077984C155574463 @default.
• W4308077984 hasConceptScore W4308077984C178790620 @default.
• W4308077984 hasConceptScore W4308077984C181389837 @default.
• W4308077984 hasConceptScore W4308077984C18150654 @default.
• W4308077984 hasConceptScore W4308077984C185592680 @default.
• W4308077984 hasConceptScore W4308077984C207001950 @default.
• W4308077984 hasConceptScore W4308077984C2777252647 @default.
• W4308077984 hasConceptScore W4308077984C2778004101 @default.
• W4308077984 hasConceptScore W4308077984C2779054382 @default.
• W4308077984 hasConceptScore W4308077984C2779820397 @default.
• W4308077984 hasConceptScore W4308077984C41625074 @default.
• W4308077984 hasConceptScore W4308077984C43617362 @default.
• W4308077984 hasConceptScore W4308077984C50670333 @default.
• W4308077984 hasConceptScore W4308077984C55493867 @default.
• W4308077984 hasConceptScore W4308077984C71924100 @default.
• W4308077984 hasConceptScore W4308077984C72918618 @default.
• W4308077984 hasConceptScore W4308077984C86803240 @default.
• W4308077984 hasConceptScore W4308077984C98274493 @default.
• W4308077984 hasIssue "11" @default.
• W4308077984 hasLocation W43080779841 @default.
• W4308077984 hasLocation W43080779842 @default.

• next