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- W4308100877 abstract "In this research paper, fatty acid-based deep eutectic solvents (FA-DESs) were prepared and investigated for the extraction of butylparaben (BP) from cosmetic products by air assisted liquid liquid microextraction (AA-DLLME). The amounts of BP were determined by UV/Vis spectrophotometry. By combining single factor optimization and Box-Behnken design based multivariate approach, key extraction parameters affecting the FA-DES AA-LLME procedure were systematically optimized. Under the optimized conditions, wide working range (5–800 μg L −1 ) was obtained with a good r 2 :0.9972 and high enrichment factor (205). For three replications run of 10 μg L −1 (low), 300 μg L −1 (medium) and 600 μg L −1 (high) of BP, the percent extraction recovery and relative standard deviation were in the range of 92 ± 4%-98 ± 2% and 1.8–2.6%, respectively. The limit of detection and the limit of quantification were 1.5 μg L −1 and 5 μg L −1 , respectively. The study of the matrix effect showed that the proposed method has high selectivity for measuring BP in the selected samples. Therefore, it has great potential in sample pre-treatment and quantification of trace BP in cosmetic products. • Fatty acid-based deep eutectic solvents were used as the extraction solvent. • Analysis of butyl paraben based on FA-DESs was developed. • The optimized procedure performed well in high-matrix samples without heating step. • AA-LLME procedure was optimized by Box-Behnken design. • The detection limit of 1.5 μg L −1 and wide working range of 5–800 μg L −1" @default.
- W4308100877 created "2022-11-08" @default.
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- W4308100877 date "2022-12-01" @default.
- W4308100877 modified "2023-09-29" @default.
- W4308100877 title "Investigation of the applicability of fatty acid-based deep eutectic solvent based air assisted liquid liquid microextraction for the rapid determination and extraction of butylparaben in cosmetic products" @default.
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- W4308100877 doi "https://doi.org/10.1016/j.scp.2022.100884" @default.
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