Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308121374> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4308121374 endingPage "3418" @default.
- W4308121374 startingPage "3418" @default.
- W4308121374 abstract "Dietary habits have a great impact on one’s health, especially in cognitive decline. Tomato and lemon contain diverse bioactive compounds and possess various effects, including the enhancement of cognitive function. We observed the protective effect of tomato, lemon extract and the mixture of them on H2O2-induced cytotoxicity of PC12 cells. To measure the in vivo effect in a murine model, each extract was orally administered to forty 1-year-old mice for 6 weeks, and a novel object recognition (NOR) test was performed to observe cognitive function, and hippocampal neurogenesis was observed through a doublecortin (DCX) stain. PC12 cell death by oxidative stress was reduced by pretreating with each extract, and a synergistic reduction was observed in the mixture. Newly generated DCX-positive neurons were synergistically increased in the hippocampus by the mixture. NOR test showed a tendency to significantly improve age-related cognitive dysfunction by consuming the mixture of tomato and lemon. In conclusion, tomato and lemon extracts can reduce cellular oxidative stress and increase NOR, likely due to enhanced neurogenesis, while the mixture of the two showed synergistic anti-oxidative effects and hippocampal neurogenesis." @default.
- W4308121374 created "2022-11-08" @default.
- W4308121374 creator A5006899756 @default.
- W4308121374 creator A5037542929 @default.
- W4308121374 creator A5041220875 @default.
- W4308121374 creator A5051628174 @default.
- W4308121374 creator A5056846121 @default.
- W4308121374 creator A5091628314 @default.
- W4308121374 date "2022-10-28" @default.
- W4308121374 modified "2023-09-25" @default.
- W4308121374 title "Mixture of Tomato and Lemon Extracts Synergistically Prevents PC12 Cell Death from Oxidative Stress and Improves Hippocampal Neurogenesis in Aged Mice" @default.
- W4308121374 cites W1000383428 @default.
- W4308121374 cites W1977305041 @default.
- W4308121374 cites W1979017394 @default.
- W4308121374 cites W1994064345 @default.
- W4308121374 cites W2002369606 @default.
- W4308121374 cites W2003966687 @default.
- W4308121374 cites W2048965112 @default.
- W4308121374 cites W2050794707 @default.
- W4308121374 cites W2069670237 @default.
- W4308121374 cites W2070581123 @default.
- W4308121374 cites W2085117007 @default.
- W4308121374 cites W2088327041 @default.
- W4308121374 cites W2097896616 @default.
- W4308121374 cites W2114324710 @default.
- W4308121374 cites W2148727841 @default.
- W4308121374 cites W2290466312 @default.
- W4308121374 cites W2544486419 @default.
- W4308121374 cites W2593977293 @default.
- W4308121374 cites W2783583681 @default.
- W4308121374 cites W2792455259 @default.
- W4308121374 cites W2934838553 @default.
- W4308121374 cites W3007803049 @default.
- W4308121374 cites W3011984121 @default.
- W4308121374 cites W3145264873 @default.
- W4308121374 cites W3152849972 @default.
- W4308121374 doi "https://doi.org/10.3390/foods11213418" @default.
- W4308121374 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36360028" @default.
- W4308121374 hasPublicationYear "2022" @default.
- W4308121374 type Work @default.
- W4308121374 citedByCount "0" @default.
- W4308121374 crossrefType "journal-article" @default.
- W4308121374 hasAuthorship W4308121374A5006899756 @default.
- W4308121374 hasAuthorship W4308121374A5037542929 @default.
- W4308121374 hasAuthorship W4308121374A5041220875 @default.
- W4308121374 hasAuthorship W4308121374A5051628174 @default.
- W4308121374 hasAuthorship W4308121374A5056846121 @default.
- W4308121374 hasAuthorship W4308121374A5091628314 @default.
- W4308121374 hasBestOaLocation W43081213741 @default.
- W4308121374 hasConcept C134018914 @default.
- W4308121374 hasConcept C148762608 @default.
- W4308121374 hasConcept C185592680 @default.
- W4308121374 hasConcept C2776151105 @default.
- W4308121374 hasConcept C2776464000 @default.
- W4308121374 hasConcept C2781161787 @default.
- W4308121374 hasConcept C2781461022 @default.
- W4308121374 hasConcept C4746552 @default.
- W4308121374 hasConcept C55493867 @default.
- W4308121374 hasConcept C86803240 @default.
- W4308121374 hasConcept C95444343 @default.
- W4308121374 hasConcept C98274493 @default.
- W4308121374 hasConceptScore W4308121374C134018914 @default.
- W4308121374 hasConceptScore W4308121374C148762608 @default.
- W4308121374 hasConceptScore W4308121374C185592680 @default.
- W4308121374 hasConceptScore W4308121374C2776151105 @default.
- W4308121374 hasConceptScore W4308121374C2776464000 @default.
- W4308121374 hasConceptScore W4308121374C2781161787 @default.
- W4308121374 hasConceptScore W4308121374C2781461022 @default.
- W4308121374 hasConceptScore W4308121374C4746552 @default.
- W4308121374 hasConceptScore W4308121374C55493867 @default.
- W4308121374 hasConceptScore W4308121374C86803240 @default.
- W4308121374 hasConceptScore W4308121374C95444343 @default.
- W4308121374 hasConceptScore W4308121374C98274493 @default.
- W4308121374 hasIssue "21" @default.
- W4308121374 hasLocation W43081213741 @default.
- W4308121374 hasLocation W43081213742 @default.
- W4308121374 hasLocation W43081213743 @default.
- W4308121374 hasLocation W43081213744 @default.
- W4308121374 hasOpenAccess W4308121374 @default.
- W4308121374 hasPrimaryLocation W43081213741 @default.
- W4308121374 hasRelatedWork W128272490 @default.
- W4308121374 hasRelatedWork W1969766346 @default.
- W4308121374 hasRelatedWork W1974742404 @default.
- W4308121374 hasRelatedWork W2006231656 @default.
- W4308121374 hasRelatedWork W2034160931 @default.
- W4308121374 hasRelatedWork W2145413665 @default.
- W4308121374 hasRelatedWork W2331252089 @default.
- W4308121374 hasRelatedWork W2540098787 @default.
- W4308121374 hasRelatedWork W3097218148 @default.
- W4308121374 hasRelatedWork W3113185115 @default.
- W4308121374 hasVolume "11" @default.
- W4308121374 isParatext "false" @default.
- W4308121374 isRetracted "false" @default.
- W4308121374 workType "article" @default.