Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308127931> ?p ?o ?g. }
- W4308127931 endingPage "3431" @default.
- W4308127931 startingPage "3431" @default.
- W4308127931 abstract "Osteoarthritis (OA), a progressive degenerative disease of weight-bearing joints, is the second leading cause of disability in the world. Despite all the advances and research over the last years, none of the proposed strategies has been effective in generating functional and long-lasting tissue. Due to the high prevalence of OA and the urgent need for an effective and successful treatment, interest in natural products as anti-inflammatory agents, such as propolis and its components, has emerged. In this work, we estimate the biomedical potential of Portuguese propolis, evaluating the in vitro antioxidant and anti-inflammatory effects of single hydroalcoholic extracts prepared with propolis from Gerês sampled over a five-year period (2011-2015) (G.EE70 and G.EE35). The in vivo and in vitro anti-inflammatory potential of the hydroalcoholic extract of mixtures of the same samples (mG.EE70 and mG.EE35) was evaluated for the first time too. DPPH• radical scavenging and superoxide anion scavenging assays showed the strong antioxidant potential of both hydroalcoholic extracts, either prepared from single propolis samples or from the mixtures of the same samples. Results also revealed an anti-inflammatory effect of mG.EE35, both in vitro by inhibiting BSA denaturation and in vivo in the OA-induced model by improving mechanical hyperalgesia as well as the gait pattern parameters. Results further support the use of propolis blends as a better and more efficient approach to take full advantage of the bioactive potential of propolis." @default.
- W4308127931 created "2022-11-08" @default.
- W4308127931 creator A5009096550 @default.
- W4308127931 creator A5042404716 @default.
- W4308127931 creator A5054759716 @default.
- W4308127931 creator A5058301078 @default.
- W4308127931 date "2022-10-29" @default.
- W4308127931 modified "2023-10-16" @default.
- W4308127931 title "An Insight on the Biomedical Potential of Portuguese Propolis from Gerês" @default.
- W4308127931 cites W1487036716 @default.
- W4308127931 cites W1551306717 @default.
- W4308127931 cites W1583489850 @default.
- W4308127931 cites W1597246335 @default.
- W4308127931 cites W1599342152 @default.
- W4308127931 cites W1899039537 @default.
- W4308127931 cites W1963618232 @default.
- W4308127931 cites W1966037459 @default.
- W4308127931 cites W1971430703 @default.
- W4308127931 cites W1977334229 @default.
- W4308127931 cites W1978611690 @default.
- W4308127931 cites W1985004392 @default.
- W4308127931 cites W1989498585 @default.
- W4308127931 cites W1990840758 @default.
- W4308127931 cites W1994017777 @default.
- W4308127931 cites W1995329928 @default.
- W4308127931 cites W1998612866 @default.
- W4308127931 cites W2003292735 @default.
- W4308127931 cites W2008712352 @default.
- W4308127931 cites W2009005936 @default.
- W4308127931 cites W2017327790 @default.
- W4308127931 cites W2020470017 @default.
- W4308127931 cites W2021784935 @default.
- W4308127931 cites W2026212186 @default.
- W4308127931 cites W2034131386 @default.
- W4308127931 cites W2034380191 @default.
- W4308127931 cites W2038718488 @default.
- W4308127931 cites W2040270316 @default.
- W4308127931 cites W2041449084 @default.
- W4308127931 cites W2041547286 @default.
- W4308127931 cites W2046574993 @default.
- W4308127931 cites W2059103432 @default.
- W4308127931 cites W2059304827 @default.
- W4308127931 cites W2061884581 @default.
- W4308127931 cites W2063854853 @default.
- W4308127931 cites W2065853716 @default.
- W4308127931 cites W2071327669 @default.
- W4308127931 cites W2071507869 @default.
- W4308127931 cites W2074740240 @default.
- W4308127931 cites W2077090690 @default.
- W4308127931 cites W2078536112 @default.
- W4308127931 cites W2078696617 @default.
- W4308127931 cites W2083048709 @default.
- W4308127931 cites W2085911696 @default.
- W4308127931 cites W2089045264 @default.
- W4308127931 cites W2095426237 @default.
- W4308127931 cites W2099328375 @default.
- W4308127931 cites W2103249556 @default.
- W4308127931 cites W2114435502 @default.
- W4308127931 cites W2120312541 @default.
- W4308127931 cites W2146707380 @default.
- W4308127931 cites W2149876011 @default.
- W4308127931 cites W2153959372 @default.
- W4308127931 cites W2156225323 @default.
- W4308127931 cites W2161296689 @default.
- W4308127931 cites W2167845657 @default.
- W4308127931 cites W2168846495 @default.
- W4308127931 cites W2170220685 @default.
- W4308127931 cites W2171046955 @default.
- W4308127931 cites W2293537897 @default.
- W4308127931 cites W2376869518 @default.
- W4308127931 cites W2403579601 @default.
- W4308127931 cites W2507683743 @default.
- W4308127931 cites W2529031581 @default.
- W4308127931 cites W2548268704 @default.
- W4308127931 cites W2586482099 @default.
- W4308127931 cites W2601029872 @default.
- W4308127931 cites W2660688026 @default.
- W4308127931 cites W2897434365 @default.
- W4308127931 cites W2903033859 @default.
- W4308127931 cites W2966748746 @default.
- W4308127931 cites W2988683723 @default.
- W4308127931 cites W2990323267 @default.
- W4308127931 cites W3002710359 @default.
- W4308127931 cites W3005652443 @default.
- W4308127931 cites W3087917567 @default.
- W4308127931 cites W3091859671 @default.
- W4308127931 cites W3093238292 @default.
- W4308127931 cites W3125307638 @default.
- W4308127931 cites W3136097850 @default.
- W4308127931 cites W3176266713 @default.
- W4308127931 cites W3193031015 @default.
- W4308127931 cites W4210729632 @default.
- W4308127931 cites W4229056148 @default.
- W4308127931 cites W4281384315 @default.
- W4308127931 cites W4281670770 @default.
- W4308127931 cites W4294343722 @default.
- W4308127931 doi "https://doi.org/10.3390/foods11213431" @default.
- W4308127931 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36360044" @default.