Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308147515> ?p ?o ?g. }
- W4308147515 endingPage "100143" @default.
- W4308147515 startingPage "100143" @default.
- W4308147515 abstract "Brain aging causes loss of synaptic spines, neuronal apoptosis, and a reduction in neurotransmitter levels. These aging phenomena disturb cortical electrical activity and its synchronization with connected regions. Previous electroencephalography (EEG) studies reported an age-related decrease in electrical activity in the alpha frequency band at occipital, parietal, and temporal areas as well as a decrease in occipital delta activity. However, there is an ongoing debate about whether there is an increase or decrease of the activity in other frequency bands with aging due to inconsistent study findings. In this study, we aimed to detect age-related changes of cortical electrical activities in all five frequency bands (delta, theta, alpha, beta, and gamma) in a large sample of healthy subjects for the first time. Using eLORETA (exact low-resolution brain electromagnetic tomography) analysis, we applied an eLORETA source estimation method to resting-state EEG data in 147 healthy subjects (median age 55, IQR 26.5–67.0) to obtain cortical electrical activity and assessed age-related changes in this activity using correlation analysis with multiple comparison correction. The combination of the eLORETA source estimation method and correlation analysis implemented in eLORETA software detected age-related changes in specific cortical regions for each frequency band: (1) delta and theta cortical electrical activities decreased at the occipital area with age, (2) alpha cortical electrical activity decreased at the occipitoparietotemporal areas with age, (3) beta cortical electrical activity increased at the insula, sensorimotor area, supplementary motor area, premotor area, and right temporal areas with age (most significant correlation at the right insula), (4) gamma cortical electrical activity increased at the frontoparietal and left temporal areas with age. These findings extend previous EEG study findings and provide valuable information related to mechanisms of healthy aging. Overall, our findings revealed that even healthy aging greatly affects cortical electrical activities in a region-specific way." @default.
- W4308147515 created "2022-11-08" @default.
- W4308147515 creator A5005237564 @default.
- W4308147515 creator A5007539776 @default.
- W4308147515 creator A5013417778 @default.
- W4308147515 creator A5025926397 @default.
- W4308147515 creator A5046288905 @default.
- W4308147515 creator A5062165699 @default.
- W4308147515 creator A5066668200 @default.
- W4308147515 creator A5067446953 @default.
- W4308147515 date "2022-12-01" @default.
- W4308147515 modified "2023-10-14" @default.
- W4308147515 title "Cortical electrical activity changes in healthy aging using EEG-eLORETA analysis" @default.
- W4308147515 cites W1963671300 @default.
- W4308147515 cites W1970831100 @default.
- W4308147515 cites W1974855479 @default.
- W4308147515 cites W1981355297 @default.
- W4308147515 cites W1986711007 @default.
- W4308147515 cites W2018123056 @default.
- W4308147515 cites W2019016175 @default.
- W4308147515 cites W2024592322 @default.
- W4308147515 cites W2028366530 @default.
- W4308147515 cites W2034641170 @default.
- W4308147515 cites W2040758286 @default.
- W4308147515 cites W2043838018 @default.
- W4308147515 cites W2046135723 @default.
- W4308147515 cites W2054973340 @default.
- W4308147515 cites W2055345898 @default.
- W4308147515 cites W2058097045 @default.
- W4308147515 cites W2060779717 @default.
- W4308147515 cites W2065671757 @default.
- W4308147515 cites W2077695508 @default.
- W4308147515 cites W2082371233 @default.
- W4308147515 cites W2083664016 @default.
- W4308147515 cites W2098330912 @default.
- W4308147515 cites W2099823830 @default.
- W4308147515 cites W2103025655 @default.
- W4308147515 cites W2109286470 @default.
- W4308147515 cites W2119185655 @default.
- W4308147515 cites W2120864281 @default.
- W4308147515 cites W2127786259 @default.
- W4308147515 cites W2129624700 @default.
- W4308147515 cites W2132361590 @default.
- W4308147515 cites W2133947591 @default.
- W4308147515 cites W2138790588 @default.
- W4308147515 cites W2143895814 @default.
- W4308147515 cites W2147597108 @default.
- W4308147515 cites W2149561999 @default.
- W4308147515 cites W2150135821 @default.
- W4308147515 cites W2153701474 @default.
- W4308147515 cites W2155982264 @default.
- W4308147515 cites W2161244114 @default.
- W4308147515 cites W2416451487 @default.
- W4308147515 cites W2425008001 @default.
- W4308147515 cites W2604733392 @default.
- W4308147515 cites W2730178777 @default.
- W4308147515 cites W2790598060 @default.
- W4308147515 cites W2908722662 @default.
- W4308147515 cites W2952277065 @default.
- W4308147515 cites W2956011950 @default.
- W4308147515 cites W3095837022 @default.
- W4308147515 cites W3107475725 @default.
- W4308147515 doi "https://doi.org/10.1016/j.ynirp.2022.100143" @default.
- W4308147515 hasPublicationYear "2022" @default.
- W4308147515 type Work @default.
- W4308147515 citedByCount "1" @default.
- W4308147515 countsByYear W43081475152023 @default.
- W4308147515 crossrefType "journal-article" @default.
- W4308147515 hasAuthorship W4308147515A5005237564 @default.
- W4308147515 hasAuthorship W4308147515A5007539776 @default.
- W4308147515 hasAuthorship W4308147515A5013417778 @default.
- W4308147515 hasAuthorship W4308147515A5025926397 @default.
- W4308147515 hasAuthorship W4308147515A5046288905 @default.
- W4308147515 hasAuthorship W4308147515A5062165699 @default.
- W4308147515 hasAuthorship W4308147515A5066668200 @default.
- W4308147515 hasAuthorship W4308147515A5067446953 @default.
- W4308147515 hasBestOaLocation W43081475151 @default.
- W4308147515 hasConcept C120843803 @default.
- W4308147515 hasConcept C138496976 @default.
- W4308147515 hasConcept C15744967 @default.
- W4308147515 hasConcept C169760540 @default.
- W4308147515 hasConcept C171606756 @default.
- W4308147515 hasConcept C49453240 @default.
- W4308147515 hasConcept C522805319 @default.
- W4308147515 hasConcept C548259974 @default.
- W4308147515 hasConcept C64943373 @default.
- W4308147515 hasConcept C66324658 @default.
- W4308147515 hasConcept C71924100 @default.
- W4308147515 hasConceptScore W4308147515C120843803 @default.
- W4308147515 hasConceptScore W4308147515C138496976 @default.
- W4308147515 hasConceptScore W4308147515C15744967 @default.
- W4308147515 hasConceptScore W4308147515C169760540 @default.
- W4308147515 hasConceptScore W4308147515C171606756 @default.
- W4308147515 hasConceptScore W4308147515C49453240 @default.
- W4308147515 hasConceptScore W4308147515C522805319 @default.
- W4308147515 hasConceptScore W4308147515C548259974 @default.
- W4308147515 hasConceptScore W4308147515C64943373 @default.
- W4308147515 hasConceptScore W4308147515C66324658 @default.