FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308154654> ?p ?o ?g. }

• W4308154654 endingPage "273" @default.
• W4308154654 startingPage "265" @default.
• W4308154654 abstract "IntroductionOlder adults with chronic kidney disease (CKD) can have low bone mineral density (BMD) with concurrent vascular calcification. Mineral accrual by the growing skeleton may protect young people with CKD from extraosseous calcification. Our hypothesis was that children and young adults with increasing BMD do not develop vascular calcification.MethodsThis was a multicenter longitudinal study in children and young people (5–30 years) with CKD stages 4 to 5 or on dialysis. BMD was assessed by tibial peripheral quantitative computed tomography (pQCT) and lumbar spine dual-energy X-ray absorptiometry (DXA). The following cardiovascular imaging tests were undertaken: cardiac computed tomography for coronary artery calcification (CAC), ultrasound for carotid intima media thickness z-score (cIMTz), pulse wave velocity z-score (PWVz), and carotid distensibility for arterial stiffness. All measures are presented as age-adjusted and sex-adjusted z-scores.ResultsOne hundred participants (median age 13.82 years) were assessed at baseline and 57 followed up after a median of 1.45 years. Trabecular BMD z-score (TrabBMDz) decreased (P = 0.01), and there was a nonsignificant decrease in cortical BMD z-score (CortBMDz) (P = 0.09). Median cIMTz and PWVz showed nonsignificant increase (P = 0.23 and P = 0.19, respectively). The annualized increase in TrabBMDz (ΔTrabBMDz) was an independent predictor of cIMTz increase (R2 = 0.48, β = 0.40, P = 0.03). Young people who demonstrated statural growth (n = 33) had lower ΔTrabBMDz and also attenuated vascular changes compared with those with static growth (n = 24).ConclusionThis hypothesis-generating study suggests that children and young adults with CKD or on dialysis may develop vascular calcification even as their BMD increases. A presumed buffering capacity of the growing skeleton may offer some protection against extraosseous calcification." @default.
• W4308154654 created "2022-11-08" @default.
• W4308154654 creator A5011584040 @default.
• W4308154654 date "2023-02-01" @default.
• W4308154654 modified "2023-10-12" @default.
• W4308154654 title "Bone Mineral Density and Vascular Calcification in Children and Young Adults With CKD 4 to 5 or on Dialysis" @default.
• W4308154654 cites W1171710792 @default.
• W4308154654 cites W173482335 @default.
• W4308154654 cites W1864314530 @default.
• W4308154654 cites W1972584749 @default.
• W4308154654 cites W1982619140 @default.
• W4308154654 cites W1993148663 @default.
• W4308154654 cites W2010140800 @default.
• W4308154654 cites W2042256973 @default.
• W4308154654 cites W2049212536 @default.
• W4308154654 cites W2057952050 @default.
• W4308154654 cites W2062511941 @default.
• W4308154654 cites W2069926335 @default.
• W4308154654 cites W2072751592 @default.
• W4308154654 cites W2101912981 @default.
• W4308154654 cites W2107207648 @default.
• W4308154654 cites W2111094568 @default.
• W4308154654 cites W2122855609 @default.
• W4308154654 cites W2123581352 @default.
• W4308154654 cites W2130277039 @default.
• W4308154654 cites W2133514604 @default.
• W4308154654 cites W2142425484 @default.
• W4308154654 cites W2145805371 @default.
• W4308154654 cites W2148238182 @default.
• W4308154654 cites W2150242497 @default.
• W4308154654 cites W2151836782 @default.
• W4308154654 cites W2158932711 @default.
• W4308154654 cites W2166551676 @default.
• W4308154654 cites W2172159264 @default.
• W4308154654 cites W2194025880 @default.
• W4308154654 cites W2257516528 @default.
• W4308154654 cites W2271199672 @default.
• W4308154654 cites W2501362475 @default.
• W4308154654 cites W2501947360 @default.
• W4308154654 cites W2603645732 @default.
• W4308154654 cites W2744661612 @default.
• W4308154654 cites W2792154527 @default.
• W4308154654 cites W2807529376 @default.
• W4308154654 cites W2922944198 @default.
• W4308154654 cites W2953209556 @default.
• W4308154654 cites W2970819883 @default.
• W4308154654 cites W3014581030 @default.
• W4308154654 cites W3037725166 @default.
• W4308154654 cites W3048440781 @default.
• W4308154654 cites W3093852631 @default.
• W4308154654 cites W3184873872 @default.
• W4308154654 cites W3201146088 @default.
• W4308154654 cites W4281786638 @default.
• W4308154654 doi "https://doi.org/10.1016/j.ekir.2022.10.023" @default.
• W4308154654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36815116" @default.
• W4308154654 hasPublicationYear "2023" @default.
• W4308154654 type Work @default.
• W4308154654 citedByCount "3" @default.
• W4308154654 countsByYear W43081546542023 @default.
• W4308154654 crossrefType "journal-article" @default.
• W4308154654 hasAuthorship W4308154654A5011584040 @default.
• W4308154654 hasBestOaLocation W43081546541 @default.
• W4308154654 hasConcept C119857082 @default.
• W4308154654 hasConcept C126322002 @default.
• W4308154654 hasConcept C126838900 @default.
• W4308154654 hasConcept C164705383 @default.
• W4308154654 hasConcept C20256973 @default.
• W4308154654 hasConcept C205545832 @default.
• W4308154654 hasConcept C2776541429 @default.
• W4308154654 hasConcept C2776886416 @default.
• W4308154654 hasConcept C2777425516 @default.
• W4308154654 hasConcept C2778319312 @default.
• W4308154654 hasConcept C2778653478 @default.
• W4308154654 hasConcept C2779978075 @default.
• W4308154654 hasConcept C2780309369 @default.
• W4308154654 hasConcept C41008148 @default.
• W4308154654 hasConcept C71924100 @default.
• W4308154654 hasConcept C84393581 @default.
• W4308154654 hasConceptScore W4308154654C119857082 @default.
• W4308154654 hasConceptScore W4308154654C126322002 @default.
• W4308154654 hasConceptScore W4308154654C126838900 @default.
• W4308154654 hasConceptScore W4308154654C164705383 @default.
• W4308154654 hasConceptScore W4308154654C20256973 @default.
• W4308154654 hasConceptScore W4308154654C205545832 @default.
• W4308154654 hasConceptScore W4308154654C2776541429 @default.
• W4308154654 hasConceptScore W4308154654C2776886416 @default.
• W4308154654 hasConceptScore W4308154654C2777425516 @default.
• W4308154654 hasConceptScore W4308154654C2778319312 @default.
• W4308154654 hasConceptScore W4308154654C2778653478 @default.
• W4308154654 hasConceptScore W4308154654C2779978075 @default.
• W4308154654 hasConceptScore W4308154654C2780309369 @default.
• W4308154654 hasConceptScore W4308154654C41008148 @default.
• W4308154654 hasConceptScore W4308154654C71924100 @default.
• W4308154654 hasConceptScore W4308154654C84393581 @default.
• W4308154654 hasIssue "2" @default.
• W4308154654 hasLocation W43081546541 @default.
• W4308154654 hasLocation W43081546542 @default.
• W4308154654 hasLocation W43081546543 @default.

• next