Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308156981> ?p ?o ?g. }
- W4308156981 endingPage "203" @default.
- W4308156981 startingPage "197" @default.
- W4308156981 abstract "An evidence-based approach for risk stratification of subclinical atrial fibrillation (AF) and hereby AF screening is lacking. This study aimed to investigate whether established cardiovascular diseases (CVD) could help to identify the population more likely to benefit from AF screening.The LOOP Study randomized AF-naïve individuals aged ≥70 years and with additional stroke risk factors to either screening with implantable loop recorder (ILR) and subsequent anticoagulation upon detection of new-onset AF episodes ≥6 min, or usual care. In this sub-study, all participants were divided into two risk groups according to the presence/absence of CVD (defined as ischemic heart disease, heart failure, previous stroke, valvular heart disease, or peripheral artery disease).A total of 1997 (33.3%) had CVD at baseline and experienced higher incidences of stroke or systemic arterial embolism (SAE), ischemic stroke, stroke/SAE/cardiovascular death, and all-cause death (adjusted HR 1.34 [1.06-1.69], 1.31 [1.02-1.69], 1.49 [1.23-1.79], and 1.59 [1.36-1.85], respectively) than those without. For ILR screening versus usual care, there was no decrease in stroke/SAE, ischemic stroke, or stroke/SAE/cardiovascular death among participants with CVD (adjusted p-values >0.05), whereas significant reductions in these outcomes were obtained by screening among those without CVD (adjusted HR 0.64 [0.44-0.93], 0.54 [0.35-0.82], 0.64 [0.46-0.87], respectively); adjusted p-values for interaction ≤0.05.In an elderly, at-risk population, ILR screening did not prevent stroke significantly in individuals with CVD, whereas screening was associated with approximately 40% stroke risk reduction among those without CVD. However, these findings should be considered as hypothesis-generating and warrant further study." @default.
- W4308156981 created "2022-11-08" @default.
- W4308156981 creator A5001078445 @default.
- W4308156981 creator A5003069476 @default.
- W4308156981 creator A5011619847 @default.
- W4308156981 creator A5020083163 @default.
- W4308156981 creator A5027418188 @default.
- W4308156981 creator A5033436516 @default.
- W4308156981 creator A5041277234 @default.
- W4308156981 creator A5057135061 @default.
- W4308156981 creator A5063449841 @default.
- W4308156981 creator A5083156954 @default.
- W4308156981 date "2023-01-01" @default.
- W4308156981 modified "2023-09-30" @default.
- W4308156981 title "Screening for atrial fibrillation to prevent stroke in elderly individuals with or without preexisting cardiovascular disease: A post hoc analysis of the randomized LOOP Study" @default.
- W4308156981 cites W1856251393 @default.
- W4308156981 cites W1980126266 @default.
- W4308156981 cites W2004260493 @default.
- W4308156981 cites W2062802453 @default.
- W4308156981 cites W2114775432 @default.
- W4308156981 cites W2124601103 @default.
- W4308156981 cites W2138595885 @default.
- W4308156981 cites W2140141379 @default.
- W4308156981 cites W2140485936 @default.
- W4308156981 cites W2151074096 @default.
- W4308156981 cites W2154658516 @default.
- W4308156981 cites W2158604698 @default.
- W4308156981 cites W2161816738 @default.
- W4308156981 cites W2169428949 @default.
- W4308156981 cites W2262459613 @default.
- W4308156981 cites W2316167515 @default.
- W4308156981 cites W2590212354 @default.
- W4308156981 cites W2598361327 @default.
- W4308156981 cites W2601804371 @default.
- W4308156981 cites W2944133085 @default.
- W4308156981 cites W2947981184 @default.
- W4308156981 cites W2964879579 @default.
- W4308156981 cites W2989882033 @default.
- W4308156981 cites W3015282390 @default.
- W4308156981 cites W3082188176 @default.
- W4308156981 cites W3133457567 @default.
- W4308156981 cites W3164908038 @default.
- W4308156981 cites W3165856983 @default.
- W4308156981 cites W3196294155 @default.
- W4308156981 cites W3196502641 @default.
- W4308156981 cites W3196741474 @default.
- W4308156981 cites W3197233575 @default.
- W4308156981 cites W4206962963 @default.
- W4308156981 cites W4236955258 @default.
- W4308156981 cites W4286592265 @default.
- W4308156981 doi "https://doi.org/10.1016/j.ijcard.2022.10.167" @default.
- W4308156981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36328113" @default.
- W4308156981 hasPublicationYear "2023" @default.
- W4308156981 type Work @default.
- W4308156981 citedByCount "1" @default.
- W4308156981 countsByYear W43081569812023 @default.
- W4308156981 crossrefType "journal-article" @default.
- W4308156981 hasAuthorship W4308156981A5001078445 @default.
- W4308156981 hasAuthorship W4308156981A5003069476 @default.
- W4308156981 hasAuthorship W4308156981A5011619847 @default.
- W4308156981 hasAuthorship W4308156981A5020083163 @default.
- W4308156981 hasAuthorship W4308156981A5027418188 @default.
- W4308156981 hasAuthorship W4308156981A5033436516 @default.
- W4308156981 hasAuthorship W4308156981A5041277234 @default.
- W4308156981 hasAuthorship W4308156981A5057135061 @default.
- W4308156981 hasAuthorship W4308156981A5063449841 @default.
- W4308156981 hasAuthorship W4308156981A5083156954 @default.
- W4308156981 hasBestOaLocation W43081569812 @default.
- W4308156981 hasConcept C113280763 @default.
- W4308156981 hasConcept C126322002 @default.
- W4308156981 hasConcept C127413603 @default.
- W4308156981 hasConcept C164705383 @default.
- W4308156981 hasConcept C2777185221 @default.
- W4308156981 hasConcept C2778198053 @default.
- W4308156981 hasConcept C2779134260 @default.
- W4308156981 hasConcept C2779161974 @default.
- W4308156981 hasConcept C2780645631 @default.
- W4308156981 hasConcept C2908647359 @default.
- W4308156981 hasConcept C71924100 @default.
- W4308156981 hasConcept C78519656 @default.
- W4308156981 hasConcept C99454951 @default.
- W4308156981 hasConceptScore W4308156981C113280763 @default.
- W4308156981 hasConceptScore W4308156981C126322002 @default.
- W4308156981 hasConceptScore W4308156981C127413603 @default.
- W4308156981 hasConceptScore W4308156981C164705383 @default.
- W4308156981 hasConceptScore W4308156981C2777185221 @default.
- W4308156981 hasConceptScore W4308156981C2778198053 @default.
- W4308156981 hasConceptScore W4308156981C2779134260 @default.
- W4308156981 hasConceptScore W4308156981C2779161974 @default.
- W4308156981 hasConceptScore W4308156981C2780645631 @default.
- W4308156981 hasConceptScore W4308156981C2908647359 @default.
- W4308156981 hasConceptScore W4308156981C71924100 @default.
- W4308156981 hasConceptScore W4308156981C78519656 @default.
- W4308156981 hasConceptScore W4308156981C99454951 @default.
- W4308156981 hasLocation W43081569811 @default.
- W4308156981 hasLocation W43081569812 @default.
- W4308156981 hasLocation W43081569813 @default.
- W4308156981 hasLocation W43081569814 @default.