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• W4308175321 abstract "Cystic fibrosis (CF) is a multiorgan disease caused by a wide variety of mutations in the cystic fibrosis transmembrane conductance regulator gene. As treatment has progressed from symptom mitigation to targeting of specific molecular defects, genetics has played an important role in identifying the proper precision therapies for each individual. Novel therapeutic approaches are focused on expanding treatment to a greater number of individuals as well as working toward a cure. This review discusses the role of genetics in our understanding of CF with a particular emphasis on how genetics informs the exciting landscape of current and novel CF therapies." @default.
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• W4308175321 date "2022-12-01" @default.
• W4308175321 modified "2023-09-29" @default.
• W4308175321 title "Genetics of Cystic Fibrosis" @default.
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• W4308175321 doi "https://doi.org/10.1016/j.ccm.2022.06.003" @default.
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