Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308188434> ?p ?o ?g. }
- W4308188434 endingPage "e0276043" @default.
- W4308188434 startingPage "e0276043" @default.
- W4308188434 abstract "Purpose To explore the impact of gender mismatch on corneal allograft rejection and rejection-related graft failure in patients with repeat penetrating keratoplasty (PK). Methods A retrospective cohort was conducted at Ramathibodi Hospital, Bangkok, Thailand. Patients with repeat PK and follow-up period of at least 6 months were recruited. Demographic data, pre-operative ocular findings and donor information were collected. Patients were divided into 2 groups according to gender mismatch between donor and recipient (male to female vs others). Survival analysis was performed using the Kaplan-Meier method. The association between risk factors and the outcomes of graft rejection and rejection-related graft failure were analyzed using Cox proportional hazards regression. Results Of 68 patients with repeat PK, 26 patients (38.2%) were gender mismatched. There was no difference in 3-year rejection-free survival and graft survival between patients with gender mismatch and others (p = 0.698 and p = 0.402, respectively). Younger recipients (< 40 years) showed a significantly higher rejection rate compared to older recipients (hazard ratio; HR = 3.14, 95% confidence interval; CI 1.15 to 8.58), while patients with multiple PK (> 2 times) were found to be significantly associated with higher rejection-related graft failure compared to patients with 2 times or less PK (HR = 2.72, 95% CI 1.03 to 7.21). After multivariate analysis, only younger recipients demonstrated a statistical significance on graft rejection (adjusted HR = 2.86, 95% CI 1.04 to 7.84). Conclusions Gender mismatch might not impact corneal graft rejection or rejection-related graft failure in patients with repeat PK. Younger age was found to be a strong factor associated with graft rejection. Gender matching might not be compulsory for repeat PK." @default.
- W4308188434 created "2022-11-09" @default.
- W4308188434 creator A5013329979 @default.
- W4308188434 creator A5032461379 @default.
- W4308188434 creator A5036299441 @default.
- W4308188434 creator A5062229206 @default.
- W4308188434 creator A5067524932 @default.
- W4308188434 creator A5071633881 @default.
- W4308188434 date "2022-10-31" @default.
- W4308188434 modified "2023-10-14" @default.
- W4308188434 title "Impact of gender mismatch on corneal graft rejection and rejection-related graft failure in repeat penetrating keratoplasty" @default.
- W4308188434 cites W1967736776 @default.
- W4308188434 cites W1971300129 @default.
- W4308188434 cites W197764648 @default.
- W4308188434 cites W1998058668 @default.
- W4308188434 cites W2020801013 @default.
- W4308188434 cites W2031599341 @default.
- W4308188434 cites W2044306073 @default.
- W4308188434 cites W2046806013 @default.
- W4308188434 cites W2077031591 @default.
- W4308188434 cites W2081999140 @default.
- W4308188434 cites W2166550261 @default.
- W4308188434 cites W2181511066 @default.
- W4308188434 cites W2233660390 @default.
- W4308188434 cites W2322987708 @default.
- W4308188434 cites W2472908324 @default.
- W4308188434 cites W2562849785 @default.
- W4308188434 cites W2765593978 @default.
- W4308188434 cites W2794055228 @default.
- W4308188434 cites W2883657963 @default.
- W4308188434 cites W2897262940 @default.
- W4308188434 cites W29177201 @default.
- W4308188434 cites W29224037 @default.
- W4308188434 cites W3006729448 @default.
- W4308188434 cites W3087310611 @default.
- W4308188434 cites W3128808689 @default.
- W4308188434 cites W4255053507 @default.
- W4308188434 cites W4300438091 @default.
- W4308188434 doi "https://doi.org/10.1371/journal.pone.0276043" @default.
- W4308188434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36315482" @default.
- W4308188434 hasPublicationYear "2022" @default.
- W4308188434 type Work @default.
- W4308188434 citedByCount "0" @default.
- W4308188434 crossrefType "journal-article" @default.
- W4308188434 hasAuthorship W4308188434A5013329979 @default.
- W4308188434 hasAuthorship W4308188434A5032461379 @default.
- W4308188434 hasAuthorship W4308188434A5036299441 @default.
- W4308188434 hasAuthorship W4308188434A5062229206 @default.
- W4308188434 hasAuthorship W4308188434A5067524932 @default.
- W4308188434 hasAuthorship W4308188434A5071633881 @default.
- W4308188434 hasBestOaLocation W43081884341 @default.
- W4308188434 hasConcept C10515644 @default.
- W4308188434 hasConcept C118487528 @default.
- W4308188434 hasConcept C126322002 @default.
- W4308188434 hasConcept C141071460 @default.
- W4308188434 hasConcept C167135981 @default.
- W4308188434 hasConcept C207103383 @default.
- W4308188434 hasConcept C2776882836 @default.
- W4308188434 hasConcept C2910338442 @default.
- W4308188434 hasConcept C2911091166 @default.
- W4308188434 hasConcept C3019230761 @default.
- W4308188434 hasConcept C44249647 @default.
- W4308188434 hasConcept C50382708 @default.
- W4308188434 hasConcept C71924100 @default.
- W4308188434 hasConcept C72563966 @default.
- W4308188434 hasConceptScore W4308188434C10515644 @default.
- W4308188434 hasConceptScore W4308188434C118487528 @default.
- W4308188434 hasConceptScore W4308188434C126322002 @default.
- W4308188434 hasConceptScore W4308188434C141071460 @default.
- W4308188434 hasConceptScore W4308188434C167135981 @default.
- W4308188434 hasConceptScore W4308188434C207103383 @default.
- W4308188434 hasConceptScore W4308188434C2776882836 @default.
- W4308188434 hasConceptScore W4308188434C2910338442 @default.
- W4308188434 hasConceptScore W4308188434C2911091166 @default.
- W4308188434 hasConceptScore W4308188434C3019230761 @default.
- W4308188434 hasConceptScore W4308188434C44249647 @default.
- W4308188434 hasConceptScore W4308188434C50382708 @default.
- W4308188434 hasConceptScore W4308188434C71924100 @default.
- W4308188434 hasConceptScore W4308188434C72563966 @default.
- W4308188434 hasIssue "10" @default.
- W4308188434 hasLocation W43081884341 @default.
- W4308188434 hasLocation W43081884342 @default.
- W4308188434 hasLocation W43081884343 @default.
- W4308188434 hasOpenAccess W4308188434 @default.
- W4308188434 hasPrimaryLocation W43081884341 @default.
- W4308188434 hasRelatedWork W1997539222 @default.
- W4308188434 hasRelatedWork W2088206352 @default.
- W4308188434 hasRelatedWork W2119154902 @default.
- W4308188434 hasRelatedWork W2130909087 @default.
- W4308188434 hasRelatedWork W2133235702 @default.
- W4308188434 hasRelatedWork W2145587586 @default.
- W4308188434 hasRelatedWork W2203903734 @default.
- W4308188434 hasRelatedWork W2782540009 @default.
- W4308188434 hasRelatedWork W3086255011 @default.
- W4308188434 hasRelatedWork W4384497977 @default.
- W4308188434 hasVolume "17" @default.
- W4308188434 isParatext "false" @default.
- W4308188434 isRetracted "false" @default.