Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308189377> ?p ?o ?g. }
- W4308189377 endingPage "204201882211299" @default.
- W4308189377 startingPage "204201882211299" @default.
- W4308189377 abstract "Cardiovascular disease is the leading cause of death worldwide; however, women tend to be less affected than men during their reproductive years. The female cardiovascular risk increases significantly around the time of the menopausal transition. The loss of the protective action of ovarian oestrogens and the circulating androgens has been implicated in possibly inducing subclinical and overt changes in the cardiovascular system after the menopausal transition. In vitro studies performed in human or animal cell lines demonstrate an adverse effect of testosterone on endothelial cell function and nitric oxide bioavailability. Cohort studies evaluating associations between testosterone and/or dehydroepiandrosterone and subclinical vascular disease and clinical cardiovascular events show an increased risk for women with more pronounced androgenicity. However, a mediating effect of insulin resistance is possible. Data on cardiovascular implications following low-dose testosterone treatment in middle-aged women or high-dose testosterone supplementation for gender affirmatory purposes remain primarily inconsistent. It is prudent to consider the possible adverse association between testosterone and endothelial function during the decision-making process of the most appropriate treatment for a postmenopausal woman." @default.
- W4308189377 created "2022-11-09" @default.
- W4308189377 creator A5051832898 @default.
- W4308189377 creator A5084991470 @default.
- W4308189377 date "2022-01-01" @default.
- W4308189377 modified "2023-10-01" @default.
- W4308189377 title "Menopause, androgens, and cardiovascular ageing: a narrative review" @default.
- W4308189377 cites W1479924026 @default.
- W4308189377 cites W1708843578 @default.
- W4308189377 cites W1844152330 @default.
- W4308189377 cites W1935921942 @default.
- W4308189377 cites W194639418 @default.
- W4308189377 cites W1948381122 @default.
- W4308189377 cites W1968265290 @default.
- W4308189377 cites W1970423626 @default.
- W4308189377 cites W1971276188 @default.
- W4308189377 cites W1973053346 @default.
- W4308189377 cites W1975521274 @default.
- W4308189377 cites W1981474747 @default.
- W4308189377 cites W1986926170 @default.
- W4308189377 cites W1993318146 @default.
- W4308189377 cites W2002925765 @default.
- W4308189377 cites W2006856548 @default.
- W4308189377 cites W2012535717 @default.
- W4308189377 cites W2017925849 @default.
- W4308189377 cites W2022453849 @default.
- W4308189377 cites W2022744504 @default.
- W4308189377 cites W2025353414 @default.
- W4308189377 cites W2026135073 @default.
- W4308189377 cites W2042366932 @default.
- W4308189377 cites W2047882048 @default.
- W4308189377 cites W2049940982 @default.
- W4308189377 cites W2050311805 @default.
- W4308189377 cites W2056113945 @default.
- W4308189377 cites W2058530820 @default.
- W4308189377 cites W2067895859 @default.
- W4308189377 cites W2073253133 @default.
- W4308189377 cites W2080953895 @default.
- W4308189377 cites W2081225653 @default.
- W4308189377 cites W2082413756 @default.
- W4308189377 cites W2084427022 @default.
- W4308189377 cites W2091759481 @default.
- W4308189377 cites W2102624326 @default.
- W4308189377 cites W2103911945 @default.
- W4308189377 cites W2113195719 @default.
- W4308189377 cites W2117558302 @default.
- W4308189377 cites W2119473645 @default.
- W4308189377 cites W2125048315 @default.
- W4308189377 cites W2128155491 @default.
- W4308189377 cites W2130045017 @default.
- W4308189377 cites W2133047862 @default.
- W4308189377 cites W2136504228 @default.
- W4308189377 cites W2139039389 @default.
- W4308189377 cites W2142194547 @default.
- W4308189377 cites W2149975928 @default.
- W4308189377 cites W2150842621 @default.
- W4308189377 cites W2155209792 @default.
- W4308189377 cites W2158519975 @default.
- W4308189377 cites W2166665238 @default.
- W4308189377 cites W2170635955 @default.
- W4308189377 cites W2227846248 @default.
- W4308189377 cites W2275204317 @default.
- W4308189377 cites W2283824511 @default.
- W4308189377 cites W2284532998 @default.
- W4308189377 cites W2305358135 @default.
- W4308189377 cites W2322013810 @default.
- W4308189377 cites W2340630518 @default.
- W4308189377 cites W2343578093 @default.
- W4308189377 cites W2403381386 @default.
- W4308189377 cites W2461437527 @default.
- W4308189377 cites W2464503047 @default.
- W4308189377 cites W2510064153 @default.
- W4308189377 cites W2520538161 @default.
- W4308189377 cites W2534457406 @default.
- W4308189377 cites W2589025836 @default.
- W4308189377 cites W2591044146 @default.
- W4308189377 cites W2606750738 @default.
- W4308189377 cites W2621371007 @default.
- W4308189377 cites W2626757669 @default.
- W4308189377 cites W2735875527 @default.
- W4308189377 cites W2754833543 @default.
- W4308189377 cites W2763916197 @default.
- W4308189377 cites W2767285808 @default.
- W4308189377 cites W2786716257 @default.
- W4308189377 cites W2791273878 @default.
- W4308189377 cites W2794092650 @default.
- W4308189377 cites W2799986334 @default.
- W4308189377 cites W2801693799 @default.
- W4308189377 cites W2805138198 @default.
- W4308189377 cites W2865707913 @default.
- W4308189377 cites W2890984537 @default.
- W4308189377 cites W2894314149 @default.
- W4308189377 cites W2899037777 @default.
- W4308189377 cites W2913705661 @default.
- W4308189377 cites W2922806183 @default.
- W4308189377 cites W2932543549 @default.
- W4308189377 cites W2947064116 @default.
- W4308189377 cites W2948761376 @default.