FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4308192221> ?p ?o ?g. }

• W4308192221 abstract "Abstract Nanoparticles are widely used in biomedical applications and cancer treatments due to their minute scale, multi-function, and long retention time. Among the various nanoparticles, the unique optical property derived from the localized surface plasmon resonance effect of metallic nanoparticles is a primary reason that metallic nanoparticles are researched and applied. Copper and Iron nanoparticles have the potential to generate hydroxyl radicals in excess H 2 O 2 via Fenton or Fenton-like reactions. On the other hand, gold nanoparticles equipped with a photosensitizer can transfer the energy of photons to chemical energy and enhance the production of singlet oxygen, which is suitable for cancer treatment. With the actions of these two reactive oxygen species in the tumor microenvironment, cell apoptosis can further be induced. In this work, we first synthesized dual metal nanoparticles with poly[styrene-alt-(maleic acid, sodium salt)(Cu ferrite oxide-polymer) by a simple one-step hydrothermal reduction reaction. Then, gold(III) was reduced and doped into the structure, which formed a triple metal structure, Au-doped Cu ferrite nanoparticles (Au/Cu ferrite oxide-polymer NPs). The metal ratio of the product could be controlled by manipulating the Fe/Cu ratio of reactants and the sequence of addition of reactants. The core–shell structure was verified by transmission electron microscopy. Moreover, the hydroxyl radical and singlet oxygen generation ability of Au/Cu ferrite oxide-polymer was proved. The chemodynamic and photodynamic effect was measured, and the in vitro ROS generation was observed. Furthermore, the behavior of endocytosis by cancer cells could be controlled by the magnetic field. The result indicated that Au/Cu ferrite oxide-polymer core–shell nanoreactor is a potential agent for chemodynamic/photodynamic synergetic therapy." @default.
• W4308192221 created "2022-11-09" @default.
• W4308192221 creator A5023705325 @default.
• W4308192221 creator A5047629145 @default.
• W4308192221 creator A5053449887 @default.
• W4308192221 creator A5057974261 @default.
• W4308192221 creator A5062876609 @default.
• W4308192221 creator A5065084312 @default.
• W4308192221 creator A5071538358 @default.
• W4308192221 creator A5077450325 @default.
• W4308192221 creator A5088030938 @default.
• W4308192221 date "2022-11-04" @default.
• W4308192221 modified "2023-09-27" @default.
• W4308192221 title "Fabrication of an Au-doped Cu/Fe oxide-polymer core–shell nanoreactor with chemodynamic and photodynamic dual effects as potential cancer therapeutic agents" @default.
• W4308192221 cites W1596848781 @default.
• W4308192221 cites W1967580039 @default.
• W4308192221 cites W1988045996 @default.
• W4308192221 cites W1989834585 @default.
• W4308192221 cites W2021713080 @default.
• W4308192221 cites W2024457833 @default.
• W4308192221 cites W2035900304 @default.
• W4308192221 cites W2039689914 @default.
• W4308192221 cites W2044191063 @default.
• W4308192221 cites W2067389663 @default.
• W4308192221 cites W2081409131 @default.
• W4308192221 cites W2082016750 @default.
• W4308192221 cites W2091854840 @default.
• W4308192221 cites W2102619095 @default.
• W4308192221 cites W2108615682 @default.
• W4308192221 cites W2129998516 @default.
• W4308192221 cites W2132719707 @default.
• W4308192221 cites W2152366705 @default.
• W4308192221 cites W2293461885 @default.
• W4308192221 cites W2293711832 @default.
• W4308192221 cites W2312982307 @default.
• W4308192221 cites W2394722219 @default.
• W4308192221 cites W2480219688 @default.
• W4308192221 cites W2559910885 @default.
• W4308192221 cites W2571579724 @default.
• W4308192221 cites W2584852739 @default.
• W4308192221 cites W2685411876 @default.
• W4308192221 cites W2737747938 @default.
• W4308192221 cites W2737866071 @default.
• W4308192221 cites W2769168471 @default.
• W4308192221 cites W2771155547 @default.
• W4308192221 cites W2782131049 @default.
• W4308192221 cites W2796462384 @default.
• W4308192221 cites W2800971234 @default.
• W4308192221 cites W2883440571 @default.
• W4308192221 cites W2887089980 @default.
• W4308192221 cites W2887202105 @default.
• W4308192221 cites W2903659409 @default.
• W4308192221 cites W2939714203 @default.
• W4308192221 cites W2975339506 @default.
• W4308192221 cites W3010874234 @default.
• W4308192221 cites W312371692 @default.
• W4308192221 cites W4250743572 @default.
• W4308192221 cites W4283835100 @default.
• W4308192221 cites W3109683385 @default.
• W4308192221 doi "https://doi.org/10.1038/s41598-022-23002-5" @default.
• W4308192221 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36333398" @default.
• W4308192221 hasPublicationYear "2022" @default.
• W4308192221 type Work @default.
• W4308192221 citedByCount "1" @default.
• W4308192221 countsByYear W43081922212023 @default.
• W4308192221 crossrefType "journal-article" @default.
• W4308192221 hasAuthorship W4308192221A5023705325 @default.
• W4308192221 hasAuthorship W4308192221A5047629145 @default.
• W4308192221 hasAuthorship W4308192221A5053449887 @default.
• W4308192221 hasAuthorship W4308192221A5057974261 @default.
• W4308192221 hasAuthorship W4308192221A5062876609 @default.
• W4308192221 hasAuthorship W4308192221A5065084312 @default.
• W4308192221 hasAuthorship W4308192221A5071538358 @default.
• W4308192221 hasAuthorship W4308192221A5077450325 @default.
• W4308192221 hasAuthorship W4308192221A5088030938 @default.
• W4308192221 hasBestOaLocation W43081922211 @default.
• W4308192221 hasConcept C155672457 @default.
• W4308192221 hasConcept C159985019 @default.
• W4308192221 hasConcept C171250308 @default.
• W4308192221 hasConcept C178790620 @default.
• W4308192221 hasConcept C185592680 @default.
• W4308192221 hasConcept C190818770 @default.
• W4308192221 hasConcept C192562407 @default.
• W4308192221 hasConcept C2777516457 @default.
• W4308192221 hasConcept C2781469039 @default.
• W4308192221 hasConcept C521977710 @default.
• W4308192221 hasConcept C540031477 @default.
• W4308192221 hasConcept C75473681 @default.
• W4308192221 hasConceptScore W4308192221C155672457 @default.
• W4308192221 hasConceptScore W4308192221C159985019 @default.
• W4308192221 hasConceptScore W4308192221C171250308 @default.
• W4308192221 hasConceptScore W4308192221C178790620 @default.
• W4308192221 hasConceptScore W4308192221C185592680 @default.
• W4308192221 hasConceptScore W4308192221C190818770 @default.
• W4308192221 hasConceptScore W4308192221C192562407 @default.
• W4308192221 hasConceptScore W4308192221C2777516457 @default.
• W4308192221 hasConceptScore W4308192221C2781469039 @default.
• W4308192221 hasConceptScore W4308192221C521977710 @default.
• W4308192221 hasConceptScore W4308192221C540031477 @default.
• W4308192221 hasConceptScore W4308192221C75473681 @default.

• next