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- W4308204059 endingPage "100623" @default.
- W4308204059 startingPage "100623" @default.
- W4308204059 abstract "Chronic hepatitis B virus disproportionately affects migrant communities in high-income countries, reflecting increased migration from sub-Saharan Africa. Chronic hepatitis B virus is endemic in sub-Saharan Africa, yet the natural history of chronic infection experienced by patients remains incompletely understood, with evidence of variability across genotypes and regions within sub-Saharan Africa. Clinical guidelines recommending treatment thresholds are not specific to sub-Saharan African patients and are based on natural history studies from Western Pacific Asian countries. Access to standard of care treatment is available for sub-Saharan African people with chronic hepatitis B virus infection in high-income countries; however, the evidence base for these treatments was not established in this cohort and areas of uncertainty remain, particularly regarding HCC surveillance and treatment discontinuation. Participation in phase III clinical trials for chronic hepatitis B therapies is almost non-existent amongst sub-Saharan African patients, even when residing in high-income countries that participate in multicentre trials. Engagement with sub-Saharan African patients with chronic hepatitis B in high-income countries is challenging because of the stigma associated with the diagnosis, absence of routine screening systems and the complexities involved in navigating the healthcare system. Nonetheless, improved engagement is critical if we are to achieve global hepatitis B virus elimination." @default.
- W4308204059 created "2022-11-09" @default.
- W4308204059 creator A5001389322 @default.
- W4308204059 creator A5033612328 @default.
- W4308204059 creator A5052742729 @default.
- W4308204059 creator A5073155315 @default.
- W4308204059 date "2023-02-01" @default.
- W4308204059 modified "2023-10-14" @default.
- W4308204059 title "Health inequalities in the management of chronic hepatitis B virus infection in patients from sub-Saharan Africa in high-income countries" @default.
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- W4308204059 doi "https://doi.org/10.1016/j.jhepr.2022.100623" @default.
- W4308204059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36636709" @default.
- W4308204059 hasPublicationYear "2023" @default.