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- W4308221380 abstract "Mitochondrial DNA (mtDNA) is maternally inherited and present in higher copy number in the cell than nuclear DNA (nDNA). Therefore, its main forensic applications involve samples that do not contain enough nDNA or that may derive from maternally related individuals. The past decade witnessed major technological changes and improvements in mtDNA typing including diverse Massively Parallel Sequencing (MPS) approaches. MPS-based mtDNA data are more complex and more informative than conventional Sanger-based electrophoretic sequence data. This can be used to better discern genuine signals from artefacts, heteroplasmies from other damage patterns, and nuclear elements of mtDNA form extraneous mixture contributions." @default.
- W4308221380 created "2022-11-09" @default.
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- W4308221380 date "2023-01-01" @default.
- W4308221380 modified "2023-10-18" @default.
- W4308221380 title "Mitochondrial DNA" @default.
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- W4308221380 doi "https://doi.org/10.1016/b978-0-12-823677-2.00138-0" @default.
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